Duktus bağımlı konjenital kalp hastalığı olan bir term yenidoğanda invajinasyon

Yıl 2013, Cilt: 40 Sayı: 1, 105 - 108, 01.03.2013

Banu Aydın Dilek Dilli Aysegül Zenciroğlu Derya Erdoğan İbrahim Karaman Mehmet Şah İpek Nurullah Okumuş

https://doi.org/10.5798/diclemedj.0921.2013.01.0233

Öz

Prostaglandin E1 infüzyonu, duktus bağımlı konjenital kalp hastalığı olan yenidoğanlarda ameliyat edilinceye kadar duktusu açık tutmak amacıyla yaygın olarak kul­lanılmaktadır. Prostaglandin E1 yaşam kurtarıcı bir ilactır ancak ateş, apne, bradikardi, hipotansiyon, konvülziyon, ödem ve kortikal hiperostoz gibi birçok yan etkiye de yol açabilir. İlacın doz azaltmasına yanıt veren ishal dışın­da gastrointestinal sistemle ilgili önemli yan etkisi rapor edilmemektedir. Bu yazıda duktus bağımlı konjenital kalp hastalığı olan ve olasılıkla prostaglandin tedavisi ile te­tiklenen intestinal invajinasyon gelişen bir olgu sunuldu.

Anahtar Kelimeler

Prostaglandin E1, yenidoğan, gast­rointestinal

Intussusception in a term newborn with duct-dependent congenital heart disease

Öz

Prostaglandin E1 infusion is widely used to maintain pa­tency of ductus arteriosus in newborns with duct-depen­dent congenital heart disease until surgery. Prostaglandin E1 is a lifesaving drug, but it has many side effects includ­ing fever, apnea, bradycardia, hypotension, convulsion, edema, and cortical hyperostosis. The gastrointestinal tract has not been recognized as a major site of serious adverse effects of prostaglandin E1 infusion, although diarrhea is a well-recognized side effect that usually re­sponds to dose reduction. In this report, we present a case of intestinal intussusception presumably induced by prostaglandin therapy in a newborn with duct-dependent congenital heart disease.

Anahtar Kelimeler

Prostaglandin E1, newborn, gastrointestinal

Kaynakça

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