A REVIEW OF REGENERATIVE ENDODONTICS

Öz

An alternative approach for immature necrotic permanent teeth is regenerative endodontic treatment. In this method, which is based on disinfection of the root canal system and periapical region without damaging the existing cells, the aim is to assist in the formation of new tissue within the canal after the stem cells are transported to the root canal and to induce further root development. Studies on stem cells, scaffold and signalling molecules which is triad of regenerative endodontic treatments concept are increasing nowadays thanks to intensive progress of regenerative medicine and tissue engineering. This review outlines the clinical protocols currently used and studies in regenerative endodontic procedures

Anahtar Kelimeler

• regenerative endodontic treatment
• stem cells
• calcium hydroxide
• immature teeth
• pulp necrosis

A REVIEW OF REGENERATIVE ENDODONTICS

Öz

İmmatür nekrotik daimi dişler için sunulan alternatif bir yaklaşım şekli de rejeneratif endodontik tedavidir. Kök kanalı sistemininde ve periapikal bölgede mevcut hücrelere zarar vermeden dezenfeksiyon hedeflenen bu yöntemde amaç, kök hücrelerin kök kanalına taşınmasıdır. Bu sayede kanal içinde yeni doku oluşumu indüklenerek kök gelişiminin devamlılığı hedeflenmektedir. Rejeneratif tıp ve doku mühendisliği alanındaki gelişmeler sayesinde rejeneratif endodontinin temel aldığı kök hücre, doku iskelesi ve büyüme sinyalleri triadı üzerine çalışmalar son dönemde ağırlık kazanmıştır. Bu derlemede rejeneratif endodontik tedavinin güncel protokol ve çalışmalarına yer verilmiştir.

Anahtar Kelimeler

• rejeneratif endodontik tedavi
• kök hücre
• kalsiyum hidroksit
• kök gelişimi tamamlanmamış dişler
• pulpa nekrozu

Kaynakça

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