Kedilerde Diş Çekimi Sonrası Diş Eti İyileşmesinde Düşük Seviyeli Lazer Tedavisinin Klinik Değerlendirmesi
Yıl 2025,
Cilt: 18 Sayı: 2, 182 - 188, 31.12.2025
Muhammed Mustafa Karataş
,
Nurıza Zamırbekova Erdoğan
Öz
Bu çalışmada, DYLT uygulamasının kedilerde diş ekstraksiyonu sonrası gingival doku bütünlüğü ve iyileşme süreci üzerindeki klinik etkisi araştırıldı. Çalışma materyalini, farklı ırk, cinsiyet ve ağırlıklarda rastgele seçilen 24 kedi oluşturdu. Kediler, her grupta 12 kedi olacak şekilde iki gruba ayrıldı. Birinci gruba ekstraksiyon sonrası antibiyotik ve ağrı kesici, ikinci gruba ise antibiyotik uygulaması ile 0., 4. ve 10. günlerde hasarlı tüm gingivanın tamamı 90 saniyede taranacak şekilde 4 j/cm² DYLT gerçekleştirildi. Tüm kediler postoperatif 0., 4. ve 10. günlerde gingival mukoza durumu, ölçümler ve metilen mavisi testi ile değerlendirildi. Preoperatif 0. günde mukoza durumu her iki grupta benzerdi. Postoperatif 4. günde lazer grubundaki kedilerin %41,7’sinde açık pembe mukoza gözlenirken, kontrol grubundaki tüm kedilerde kızarıklık (kısmi veya belirgin) ve ödem (lazer grubunda %8.3, kontrol grubunda %83.3) görüldü. 10. günde lazer grubundaki tüm kedilerde mukoza açık pembe ve ödemsizdi. Kontrol grubunda ise açık pembe mukoza %41.7, ödem %58.3 oranında tespit edildi. Gingival yaranın uzunlamasına ve yatay cetvelle ölçüm sonuçlarına göre iyileşme oranı, 0-4. ve 4-10. günlerde gruplar arasında anlamlı bir fark göstermiştir (p <0.001). Lazer grubunda kontrol grubuna göre anlamlı derecede daha yüksek iyileşme oranı görülmüştür. Metilen mavisi uygulamasına ait bulgulara göre, 4. günde lazer grubunda %75.6, kontrol grubunda ise %44.2 oranında gingival iyileşme gözlenmiştir. 10. günde lazer grubundaki tüm kedilerde iyileşme sağlanırken, kontrol grubunda %29.1 oranında iyileşmede gecikme görüldü. Çalışma sonuçlarına göre, 4 J/cm² enerji yoğunluğunda uygulanan DYLT, diş ekstraksiyonu sonrası kedilerde ödem ve inflamasyonu azaltarak yara iyileşmesini hızlandırmak ve oral beslenmeye dönüşü desteklemek açısından etkili bulunmuştur.
Etik Beyan
Bu çalışma, Selçuk Üniversitesi Deneyimsel Araştırma ve Uygulama Merkezi (SÜVDAMEK) tarafından 31.10.2024 tarihli ve 2024/33 numaralı onay ile gerçekleştirilmiştir. Çalışmaya dahil edilen kedilerin sahiplerine, kedilerinin projeye katılması durumunda venöz erişim sağlanacağı ve hematolojik parametreler, kan gazı analizi, hematokrit ve biyokimyasal tarama dahil olmak üzere laboratuvar analizi için kan örnekleri alınacağı bildirilmiştir. Ayrıntılı klinik ve radyografik muayeneleri kolaylaştırmak için sedasyon veya genel anestezi de uygulanacaktır. Sahipler, bu prosedürleri kabul ettiklerini teyit eden yazılı bilgilendirilmiş onam formu imzalamışlardır.
Destekleyen Kurum
Bu çalışma, Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (TÜBİTAK) tarafından B.14.2.TBT.0.06.01.00-221-760956 numaralı proje kapsamında finanse edilmiştir.
Proje Numarası
1919B012401100
Teşekkür
Bu projeye desteklerinden dolayı TÜBİTAK'a teşekkür ederiz.
Kaynakça
-
Ho J, Hussain S, Sparagano O (2021). Did the COVID-19 pandemic spark a public interest in pet adoption. Front Vet Sci., 8:647308.
-
Kim CG, Kwon D, Lee K, et al (2025). The prevalence of reasons for tooth extraction in cats. Front Vet Sci., 12:1626701.
-
Kim CG, Kwon D, Lee K, et al (2025). Prevalence of reasons for tooth extraction in small- and medium-breed dogs. Animals, 15(2):224.
-
Palmeira I, Fonseca MJ, Lafont-Lecuelle C, et al (2022). Dental pain in cats: a prospective 6-month study. J Vet Dent., 39(4):369–375.
-
American Veterinary Dental College (2025) AVDC nomenclature. Teeth abnormalities and related procedures. Erişim: https://avdc.org/avdc-nomenclature/. Erişim tarihi: 29.04.2025.
-
Kuculmez O, Dündar Ahi E, Coşar SN, et al (2024). Servikal disk hernisi tedavisinde yüksek frekanslı lazer terapisinin fizyoterapiye alternatif olarak değerlendirilmesi. Front Med., 11:1429660.
-
Kamlangchai P, Kampa N, Srithunyarat T, et al (2024). Assessing the potential efficacy of 830-nanometer low-level laser therapy in cats: Extraoral applications. Vet World, 17(5):1124–1129.
-
Niemiec BA (2013). Veterinary dental radiology. In: Dental, Oral, and Maxillofacial Diseases in Small Animals. Deprem O, Yeşildere T (eds). 2nd ed. Nobel, Ankara, Türkiye., 64-79.
-
Kohale BR, Agrawal AA, Raut CP (2018). Effect of low-level laser therapy on wound healing and patients' response after scalpel gingivectomy: a randomized clinical split-mouth study. J Indian Soc Periodontol., 22(5):419–426.
-
Taha N, Dündar Ahi E, Coşar SN, et al (2024). Düşük seviyeli lazer terapisinin yara iyileşmesi ve ağrı üzerindeki etkileri: Bir meta-analiz. Front Med., 11:11602420.
-
Ahrari F, Eshghpour M, Zare R, et al (2020). Effectiveness of low-level laser irradiation in reducing complications following tooth extraction. J Lasers Med Sci., 11(1):1–6.
-
Abesi F, El-Sayed H, Al-Fakharany AH, et al (2023). Efficacy of low-level laser therapy in wound healing and postoperative pain reduction: A meta-analysis. Front Med., 10:11602420.
-
Winkler CJ, Miller LA (2025). Oral condition: Feline stomatitis. In: Periodontal Disease Laser Therapy in Veterinary Medicine: Photobiomodulation, Thompson AB (ed.), 2nd ed., Wiley, New Jersey, 163–172.
-
Hamblin, M. R. (2018). Mechanisms and mitochondrial redox signaling in photobiomodulation. Photobiomodul Photomed Laser Surg., 36(8), 395–396.
-
Hamblin, M. R. (2017). Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics, 4(3):337–361.
-
Busnardo VL, Biondo-Simões ML (2010). Effects of low-level helium-neon laser on induced wound healing in rats. Rev Bras Fisioter., 14(1):45–51.
-
Keerti N, Bhargava MK, Madhu S, Dharmendra K, Bhowmick D (2016). Low level laser therapy for healing of aural haematoma in dogs. Intas Polivet., 2:262–269.
-
Gammel JE, Biskup JJ, Drum MG, Newkirk Kim Lux CN (2018). Effects of low-level laser therapy on the healing of surgically closed incisions and surgically created open wounds in dogs. Vet Surg., 47:499–506.
-
Petersen SL, Botes C, Olivier A, et al (1999). The effect of low level laser therapy (DYLT) on wound healing in horses. Equine Vet J., 31:228–231.
Clinical Evaluation of Low-Level Laser Therapy in Gingival Healing After Tooth Extraction in Cats
Yıl 2025,
Cilt: 18 Sayı: 2, 182 - 188, 31.12.2025
Muhammed Mustafa Karataş
,
Nurıza Zamırbekova Erdoğan
Öz
This study investigated the clinical effects of low-intensity laser therapy (LLLT) on gingival tissue integrity and healing following tooth extraction in cats. Twenty-four cats of different breeds, genders and weights were randomly selected for the study. The cats were divided into two groups, with 12 cats in each group. The first group received antibiotics and painkillers after extraction, while the second group received antibiotics and underwent DYLT at 4 J/cm² on days 0, 4, and 10, scanning the entire damaged gingiva for 90 seconds. The cats were evaluated on postoperative days 0, 4 and 10 using gingival mucosa measurements and the methylene blue test. Preoperatively, on day 0, the mucosal condition was similar in both groups. On postoperative day 4, bright pink mucosa was observed in 41.7% of cats in the laser group. By contrast, all cats in the control group showed redness (either partial or severe) and oedema (8.3% of cats in the laser group versus 83.3% in the control group). By day 10, the mucosa was bright pink and swollen in all cats in the laser group. In the control group, light pink mucosa was observed in 41.7% of cats, with oedema observed in 58.3%. The healing rate of the gingival wound, measured using longitudinal and horizontal rulers, showed a significant difference between the groups on days 0-4 and 4-10 (p <0.001). A significantly higher healing rate was observed in the laser group compared to the control group. According to the methylene blue findings, gingival healing was observed in 75.6% of cats in the laser group and 44.2% of cats in the control group on day 4. While all cats in the laser group had recovered by day 10, healing was delayed in 29.1% of the control group. In conclusion, applying LLLT at an energy density of 4 J/cm² was found to be effective in accelerating wound healing and supporting the return to oral feeding after tooth extraction in cats, by reducing oedema and inflammation.
Etik Beyan
This study was conducted with the approval of Selcuk University Experimental Research and Application Center (SÜVDAMEK), dated 31.10.2024 and numbered 2024/33. The owners of the cats included in the study were informed that if their cats participated in the project, venous access would be established and blood samples would be collected for laboratory analysis, including haematological parameters, blood gas analysis, haematocrit and biochemical screening. Sedation or general anaesthesia would also be administered to facilitate detailed clinical and radiographic examinations. Written informed consent was provided by the owners, confirming their agreement to these procedures.
Destekleyen Kurum
This study was funded by the Scientific and Technological Research Council of Turkey (TÜBİTAK) as part of project B.14.2.TBT.0.06.01.00-221-760956.
Proje Numarası
1919B012401100
Teşekkür
We would like to thank TÜBİTAK for their support of this project.
Kaynakça
-
Ho J, Hussain S, Sparagano O (2021). Did the COVID-19 pandemic spark a public interest in pet adoption. Front Vet Sci., 8:647308.
-
Kim CG, Kwon D, Lee K, et al (2025). The prevalence of reasons for tooth extraction in cats. Front Vet Sci., 12:1626701.
-
Kim CG, Kwon D, Lee K, et al (2025). Prevalence of reasons for tooth extraction in small- and medium-breed dogs. Animals, 15(2):224.
-
Palmeira I, Fonseca MJ, Lafont-Lecuelle C, et al (2022). Dental pain in cats: a prospective 6-month study. J Vet Dent., 39(4):369–375.
-
American Veterinary Dental College (2025) AVDC nomenclature. Teeth abnormalities and related procedures. Erişim: https://avdc.org/avdc-nomenclature/. Erişim tarihi: 29.04.2025.
-
Kuculmez O, Dündar Ahi E, Coşar SN, et al (2024). Servikal disk hernisi tedavisinde yüksek frekanslı lazer terapisinin fizyoterapiye alternatif olarak değerlendirilmesi. Front Med., 11:1429660.
-
Kamlangchai P, Kampa N, Srithunyarat T, et al (2024). Assessing the potential efficacy of 830-nanometer low-level laser therapy in cats: Extraoral applications. Vet World, 17(5):1124–1129.
-
Niemiec BA (2013). Veterinary dental radiology. In: Dental, Oral, and Maxillofacial Diseases in Small Animals. Deprem O, Yeşildere T (eds). 2nd ed. Nobel, Ankara, Türkiye., 64-79.
-
Kohale BR, Agrawal AA, Raut CP (2018). Effect of low-level laser therapy on wound healing and patients' response after scalpel gingivectomy: a randomized clinical split-mouth study. J Indian Soc Periodontol., 22(5):419–426.
-
Taha N, Dündar Ahi E, Coşar SN, et al (2024). Düşük seviyeli lazer terapisinin yara iyileşmesi ve ağrı üzerindeki etkileri: Bir meta-analiz. Front Med., 11:11602420.
-
Ahrari F, Eshghpour M, Zare R, et al (2020). Effectiveness of low-level laser irradiation in reducing complications following tooth extraction. J Lasers Med Sci., 11(1):1–6.
-
Abesi F, El-Sayed H, Al-Fakharany AH, et al (2023). Efficacy of low-level laser therapy in wound healing and postoperative pain reduction: A meta-analysis. Front Med., 10:11602420.
-
Winkler CJ, Miller LA (2025). Oral condition: Feline stomatitis. In: Periodontal Disease Laser Therapy in Veterinary Medicine: Photobiomodulation, Thompson AB (ed.), 2nd ed., Wiley, New Jersey, 163–172.
-
Hamblin, M. R. (2018). Mechanisms and mitochondrial redox signaling in photobiomodulation. Photobiomodul Photomed Laser Surg., 36(8), 395–396.
-
Hamblin, M. R. (2017). Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS Biophysics, 4(3):337–361.
-
Busnardo VL, Biondo-Simões ML (2010). Effects of low-level helium-neon laser on induced wound healing in rats. Rev Bras Fisioter., 14(1):45–51.
-
Keerti N, Bhargava MK, Madhu S, Dharmendra K, Bhowmick D (2016). Low level laser therapy for healing of aural haematoma in dogs. Intas Polivet., 2:262–269.
-
Gammel JE, Biskup JJ, Drum MG, Newkirk Kim Lux CN (2018). Effects of low-level laser therapy on the healing of surgically closed incisions and surgically created open wounds in dogs. Vet Surg., 47:499–506.
-
Petersen SL, Botes C, Olivier A, et al (1999). The effect of low level laser therapy (DYLT) on wound healing in horses. Equine Vet J., 31:228–231.