Koyunlarda Gebelik ve Laktasyon Dönemlerinde C Vitamini ve Mineral Takviyesinin Bazı Hematolojik ve Biyokimyasal Parametreler Üzerine Etkisi

Öz

Ruminantlarda periparturient dönem (geç gebelik ve erken laktasyon), metabolik taleplerin arttığı ve oksidatif stresin şekillendiği kritik bir evredir. Bu çalışma; C vitamini, mineral karışımı ve bunların kombine uygulamalarının, gebelik ve laktasyon dönemindeki koyunlarda hematolojik ve bazı biyokimyasal parametreler üzerindeki etkilerini araştırdı. Araştırmada toplam 60 sağlıklı İvesi koyun rastgele dört gruba ayrıldı (n=15). G1 (kontrol) grubuna serum fizyolojik uygulanırken, G2 (C vitamini), G3 (mineral) ve G4 (C vitamini + mineral) gruplarına gebeliğin 3. ayından doğuma kadar ilgili takviyeler enjekte edildi. Kan örnekleri gebeliğin 3., 4., 5. aylarında, laktasyonun 1. ve 3. aylarında toplandı. Örneklerde tam kan sayımı ile serum biyokimyasal parametreleri analiz edildi. Gruplar arasında karşılaştırmalarda; kontrol grubuna kıyasla takviye sunulan gruplarda gebelikte HGB, RBC, HCT (p<0.01), MCV, TP (p<0.05) ve Mg (p<0.001) düzeylerinde, laktasyonda ise üre (p<0.001) ve K (p<0.01) düzeylerinde istatistiksel olarak anlamlı artışlar saptandı. Aksine laktasyonda Na (p<0.05) düzeyinde azalma kaydedildi. Grup içi değerlendirmelerde; tüm çalışma gruplarında WBC, HGB, MCV, MCH, MCHC, ALP, AST, CK, LDH, TP, CREA, üre, Mg ve Na parametrelerinde zamana bağlı önemli değişimler izlendi (p<0.05). Sonuç olarak; gebelik ve laktasyon sürecindeki koyunlarda kombine vitamin-mineral karışımının (G4), hematolojik profili destekleme ve elektrolit dengesini korumada tekli uygulamalara göre daha kapsamlı bir etkinlik sergilediği saptandı.

Anahtar Kelimeler

• Biyokimyasal parametreler
• C vitamini
• gebelik
• hematoloji
• koyun
• mineral karışımı

Destekleyen Kurum

Bu çalışma, Dicle Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi tarafından desteklenmiştir (Proje No: VETERINER.22.003).

Proje Numarası

VETERİNER.22.003

Etik Beyan

Bu çalışma, Harran Üniversitesi Yerel Hayvan Deneyleri Etik Kurulu tarafından 9 Şubat 2022 tarihinde onaylanmıştır (Oturum No: 2022/001, Karar No: 01–11).

Teşekkür

Yazarlar, desteklerinden dolayı Dicle Üniversitesi Bilimsel Araştırma Projeleri Koordinasyon Birimi'ne ve değerli yardımlarından dolayı Şanlıurfa ili, Haliliye ilçesi, Dikme köyü'nde bulunan çiftliğin personeline teşekkür ederler.

Effects of Vitamin C and Mineral Supplementation on Some Hematological and Biochemical Parameters in Ewes during Pregnancy and Lactation

Öz

In ruminants, the periparturient period (late pregnancy and early lactation) is a critical phase where metabolic demands increase, and oxidative stress develops. This study investigated the effects of vitamin C, mineral mixtures, and their combined applications on hematological and some biochemical parameters in ewes during pregnancy and lactation. A total of 60 healthy İvesi ewes were randomly divided into four groups (n=15). Group G1 (control) received saline solution, while groups G2 (vitamin C), G3 (mineral), and G4 (vitamin C + mineral) received the relevant supplements from the 3rd month of pregnancy until parturition. Blood samples were collected in the 3rd, 4th, and 5th months of pregnancy, and in the 1st and 3rd months of lactation. Complete blood counts and serum biochemical parameters were analyzed in the samples. In comparisons between the groups, compared to the control group, the supplemented groups showed statistically significant increases in HGB, RBC, HCT (p<0.01), MCV, TP (p<0.05), and Mg (p<0.001) levels during pregnancy, and in urea (p<0.001) and K (p<0.01) levels during lactation. Conversely, a decrease in Na (p<0.05) levels was recorded during lactation. In within-group evaluations, significant time-dependent changes were observed in WBC, HGB, MCV, MCH, MCHC, ALP, AST, CK, LDH, TP, CREA, urea, Mg, and Na parameters in all study groups (p<0.05). In conclusion, combined vitamin-mineral mixtures (G4) in ewes during pregnancy and lactation were found to exhibit more comprehensive efficacy in supporting the hematological profile and maintaining electrolyte balance compared to single applications.

Anahtar Kelimeler

• Biochemical parameters
• ewes
• hematology
• mineral mixtures
• pregnancy
• vitamin C

Destekleyen Kurum

This study was supported by the Scientific Research Projects Coordination Unit of Dicle University (Project No: VETERINER.22.003).

Proje Numarası

VETERİNER.22.003

Etik Beyan

This study was approved by the Harran University Local Ethics Committee for Animal Experiments on 09 February 2022 (Session No: 2022/001, Decision No: 01–11).

Teşekkür

The authors would like to thank the Scientific Research Projects Coordination Unit of Dicle University for their support and the staff of the farm located in Dikme village, Haliliye district, Şanlıurfa province for their valuable assistance.

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