Effect of harvesting period on chemical and bioactive properties of royal jelly from Turkey

Yıl 2020, Cilt: 1 Sayı: 1, 9 - 12, 14.09.2020

Murat Emir

Öz

Royal jelly is a natural viscous, milky-white product which is secreted from special glands of young worker honey bees (Apis mellifera L.) used to feed queen larvae and the queen bee throughout its life. It can be used as a dietary complement because of its composition, and also it contains a large number of bioactive substances such as peptides, flavonoids, fatty acids and also 10-hydroxy-2-decenoic acid (10-HDA). The variation in chemical compounds of royal jelly depends on some factors such as floral sources, queen cup types and harvesting time. In this study, the effect of harvesting period (April, May, June, July and August) on physicochemical properties and 10-HDA content in royal jelly collected from different producers in Turkey. The total solid contents as well as protein contents of royal jelly significantly changed depend on the harvesting period, but no alteration in pH value. The maximum means of total phenolic content and antioxidant activity were found in samples harvested in July. 10-HDA content varied from 0.91% to 2.05%, with a mean of 1.38%. A significant effect of month in 10-HDA content was found, and the highest mean value observed in June.

Anahtar Kelimeler

Royal jelly, harvesting period, 10-hydroxy-2-decenoic acid (10-HDA), chemical properties, bioactive properties

Teşekkür

The authors would like to thank to the Association of Honey Promotion for financially supported and also to the Turkish Beekepers for providing the royall jelly used for in this study.

Kaynakça

• Alu'datt, M. H., Rababah, T., Obaidat, M. M., Ereifej, K., Alhamad, M. N., Mhaidat, N., . . . Ayadi, W. (2015). Probiotics in Milk as Functional Food: Characterization and Nutraceutical Properties of Extracted Phenolics and Peptides from Fermented Skimmed Milk Inoculated with Royal Jelly. Journal of Food Safety, 35(4), 509-522. doi:10.1111/jfs.12201
• Amarowicz, R., Pegg, R. B., Rahimi-Moghaddam, P., Barl, B., & Weil, J. A. (2004). Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chemistry, 84(4), 551-562. doi:10.1016/s0308-8146(03)00278-4
• Anna Gloria Sabatini, A. G., Marcazzan, L. G., Caboni, M. F., Bogdanov, S., & de Almeida-Muradian, L. B. (2009). Quality and standardisation of Royal Jelly. Journal of ApiProduct and ApiMedical Science, 1(1), 1-6. doi:10.3896/IBRA.4.1.01.04
• Antinellia, J. F., Zeggane, S., Davico, R., Rognone, C., Faucon, J. P., & Lizzani, L. (2003). Evaluation of (E)-10-hydroxydec-2-enoic acid as a freshness parameter for royal jelly. Food Chemistry, 80, 85-89.
• Balkanska, R. (2018). Determination of Trans-10-Hydroxy-2-Decenoic Acid in Royal Jelly by High Performance Liquid Chromatography after Different Bee Feeding. International Journal of Current Microbiology and Applied Sciences, 7(04), 3738-3743. doi:10.20546/ijcmas.2018.704.420
• Balkanska, R., Marghitas, L.-A., & Pavel, C. I. (2017). Antioxidant Activity and Total Polyphenol Content of Royal Jelly from Bulgaria. International Journal of Current Microbiology and Applied Sciences, 6(10), 578-585. doi:10.20546/ijcmas.2017.610.071
• Bincoletto, C., Eberlin, S., Figueiredo, C. A., Luengo, M. B., & Queiroz, M. L. (2005). Effects produced by Royal Jelly on haematopoiesis: relation with host resistance against Ehrlich ascites tumour challenge. Int Immunopharmacol, 5(4), 679-688. doi:10.1016/j.intimp.2004.11.015
• Čeksteryté, V., Kurtinaitienė, B., Venskutonis, P. R., Pukalskas, A., Kazernavičiūtė, R., & Balžekas, J. (2016). Evaluation of antioxidant activity and flavonoid composition in differently preserved bee products. Czech Journal of Food Sciences, 34(No. 2), 133-142. doi:10.17221/312/2015-cjfs
• Çakır, H. E., Şirin, Y., & Kolaylı, S. (2019). Royal Jelly and Its SDS-PAGE Electrophoresis Profiles. Journal of Apitherapy and Nature, 17-20. doi:10.35206/jan.638063
• El-Guendouz, S., Machado, A. M., Aazza, S., Lyoussi, B., Miguel, M. G., Mateus, M. C., & Figueiredo, A. C. (2020). Chemical Characterization and Biological Properties of Royal Jelly Samples From the Mediterranean Area. Natural Product Communications, 15(2). doi:10.1177/1934578x20908080
• El-Nekeety, A. A., El-Kholy, W., Abbas, N. F., Ebaid, A., Amra, H. A., & Abdel-Wahhab, M. A. (2007). Efficacy of royal jelly against the oxidative stress of fumonisin in rats. Toxicon, 50(2), 256-269. doi:10.1016/j.toxicon.2007.03.017
• Emir , M. (2017). Royal jelly in Turkey: Production, cost and marketing. 45th APIMONDIA International Apicultural Congress, 29 September–4 October, Istanbul, TURKEY.
• Inoue, S. (2003). Royal Jelly prolongs the life span of C3H/HeJ mice: correlation with reduced DNA damage. Experimental Gerontology, 38(9), 965-969. doi:10.1016/s0531-5565(03)00165-7
• ISO. (2016). International Standard. Royal jelly specifications ISO:12824:2016 (E), p. 35.
• Jie, H., Li, P. M., Zhao, G. J., Feng, X. L., Zeng, D. J., Zhang, C. L., . . . Chen, Q. (2016). Amino acid composition of royal jelly harvested at different times after larval transfer. Genet Mol Res, 15(3). doi:10.4238/gmr.15038306
• Kamakura, M., Mitani, N., Fukuda, T., & Fukushim, M. (2001). Antifatigue effect of fresh royal jelly in mice. Journal of Nutritional Science and Vitaminology, 47, 394-401.
• Kamyab, S., Gharachorloo, M., Honarvar, M., & Ghavami, M. (2019). Quantitative analysis of bioactive compounds present in Iranian royal jelly. Journal of Apicultural Research, 59(1), 42-52. doi:10.1080/00218839.2019.1673964
• Kohno, K., Okamoto, I., Sano, O., Arai, N., Iwaki, K., Ikeda, M., & Kurimoto, M. (2004). Royal jelly inhibits the production of proinflammatory cytokines by activated macrophages. Biosci Biotechnol Biochem, 68(1), 138-145. doi:10.1271/bbb.68.138
• Kolayli, S., Sahin, H., Can, Z., Yildiz, O., Malkoc, M., & Asadov, A. (2016). A Member of Complementary Medicinal Food: Anatolian Royal Jellies, Their Chemical Compositions, and Antioxidant Properties. J Evid Based Complementary Altern Med, 21(4), NP43-48. doi:10.1177/2156587215618832
• Okamoto, I., Taniguchi, Y., Kunikata, T., Kohno, K., Iwaki, K., Ikeda, M., & Kurimoto, M. (2003). Major royal jelly protein 3 modulates immune responses in vitro and in vivo. Life Sciences, 73(16), 2029-2045. doi:10.1016/s0024-3205(03)00562-9
• Ozkok, D., & Silici, S. (2017). Antioxidant activities of honeybee products and their mixtures. Food Sci Biotechnol, 26(1), 201-206. doi:10.1007/s10068-017-0027-0
• Park, H. G., Kim, B. Y., Park, M. J., Deng, Y., Choi, Y. S., Lee, K. S., & Jin, B. R. (2019). Antibacterial activity of major royal jelly proteins of the honeybee (Apis mellifera) royal jelly. Journal of Asia-Pacific Entomology, 22(3), 737-741. doi:10.1016/j.aspen.2019.06.005
• Pavel, C. I., Mărghitaş, L. A., Dezmirean, D. S., Tomoş, L. I., Bonta, V., Şapcaliu, A., & Buttstedt, A. (2015). Comparison between local and commercial royal jelly—use of antioxidant activity and 10-hydroxy-2-decenoic acid as quality parameter. Journal of Apicultural Research, 53(1), 116-123. doi:10.3896/ibra.1.53.1.12
• Ramadan, M. F., & Al-Ghamdi, A. (2012). Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of Functional Foods, 4(1), 39-52. doi:10.1016/j.jff.2011.12.007
• Silici, S., Sagdic, O., & Ekici, L. (2010). Total phenolic content, antiradical, antioxidant and antimicrobial activities of Rhododendron honeys. Food Chemistry, 121(1), 238-243. doi:10.1016/j.foodchem.2009.11.078
• Singleton, V. L., & Rossi, J. A. (1965). Colorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents. American Journal of Enology and Viticulture, 16, 144-158.
• Turkish-Standard. (2000). Royal Jelly Standard. ICS 65.140; 67.230. TS 6666.
• Vittek, V. (1995). Effect of Royal Jelly on serum lipids in experimental animals and humans with atherosclerosis. Experientia, 51, 927-935. Wongchai, V., & Ratanavalacha, T. (2002). Seasonal Variation of Chemical Composition of Royal Jelly Produced in Thailand. Thammasat International Journal of Science and Technology, 7(2), 1-8.
• Wytrychowski, M., Chenavas, S., Daniele, G., Casabianca, H., Batteau, M., Guibert, S., & Brion, B. (2013). Physicochemical characterisation of French royal jelly: Comparison with commercial royal jellies and royal jellies produced through artificial bee-feeding. Journal of Food Composition and Analysis, 29(2), 126-133. doi:10.1016/j.jfca.2012.12.002
• Yang, X., Li, Y., Wang, L., Li, L., Guo, L., Huang, F., & Zhao, H. (2019). Determination of 10-Hydroxy-2-Decenoic Acid of Royal Jelly Using Near-Infrared Spectroscopy Combined with Chemometrics. J Food Sci, 84(9), 2458-2466. doi:10.1111/1750-3841.14748
• Yavuz, İ., & Gürel, F. (2017). Chemical properties of the royal jellies in Turkish markets. Mediterranean Agricultural Sciences, 30(3), 281-285. doi:10.29136/mediterranean.360013
• Zheng, H. Q., Hu, F. L., & Dietemann, V. (2011). Changes in composition of royal jelly harvested at different times: consequences for quality standards. Apidologie, 42(1), 39-47. doi:10.1051/apido/2010033
• Zhu, Z., Zhang, Y., Wang, J., Li, X., Wang, W., & Huang, Z. (2019). Characterization of sugar composition in Chinese royal jelly by ion chromatography with pulsed amperometric detection. Journal of Food Composition and Analysis, 78, 101-107. doi:10.1016/j.jfca.2019.01.003 Zimmermann, A. (2002). Liver regeneration: the emergence of new pathways. Medical Science Monitor, 8(3), 53-63.