Araştırma Makalesi
BibTex RIS Kaynak Göster

An optimization study for processing variables in fabrication of cinnamon tincture by response surface methodology

Yıl 2022, Cilt: 3 Sayı: 2, 58 - 62, 31.12.2022
https://doi.org/10.55147/efse.1218211

Öz

In this study, effects of two processing variables namely liquid/solid ratio (3-10 mL/g) and ethanol concentration (25-75%) on total phenolic content and antiradical activity of cinnamon tincture were investigated using response surface methodology. Total phenolic content of the tincture samples ranged between 4667.9-14892.6 mg GAE/L while the IC50 values were in the range of 71.64-78.55. The effect of both liquid/solid ratio on total phenolic content of the cinnamon tincture samples was determined to be significant (p<0.05). Increase in the liquid level per gram of the cinnamon sample caused a significant decrease on the total phenolic content of the samples (p<0.05). Multiple response optimization of the processing variables showed that the maximum phenolic content could be obtained by the minimum liquid/solid ratio and for the best processing conditions of the high bioactive cinnamon tincture; liquid/solid ratio and ethanol concentration levels were determined to be 4.03 mL/g and 55.41% ethanol level. The results of the study would be an instructive for the tincture manufacturer.

Kaynakça

  • Anderson, R. A., Broadhurst, C. L., Polansky, M. M., Schmidt, W. F., Khan, A., Flanagan, V. P., ... & Graves, D. J. (2004). Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. Journal of Agricultural and Food Chemistry, 52(1), 65-70. doi: 10.1021/jf034916b
  • Bone, K. (2003). A clinical guide to blending liquid herbs: herbal formulations for the individual patient. Elsevier Health Sciences.
  • Çetin, N. (2022). Elma dilimlerinin konvektif kurutulmasinda enerji özelliklerine etki eden faktörlerin yanit yüzeyi yöntemi ile değerlendirilmesi. Bursa Uludağ Üniversitesi Ziraat Fakültesi Dergisi, 36(2), 265-283. doi: 10.20479/bursauludagziraat.1051109
  • Kaplan, M., Yilmaz, M. M., Köprü, S., Gözelle, H., Muhderem, G. & Uslu, R. (2018). Sıvı/katı oranı ve etanol konsantrasyonuna göre karahindiba (Taraxacum officinale) tentürünün verim ve biyoaktivitesindeki değişimin incelenmesi. Türk Tarım ve Doğa Bilimleri Dergisi, 5(2), 163-174. doi: 10.30910/turkjans.421360
  • Karaman, K. & Sagdic, O. (2019). Zygosaccharomyces bailii and Z. rouxii induced ethanol formation in apple juice supplemented with different natural preservatives: A response surface methodology approach. Journal of Microbiological Methods, 163, 105659. doi: 10.1016/j.mimet.2019.105659
  • Koch, E. & Malek, F. A. (2011). Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders–preclinical and clinical studies. Planta Medica, 77(11), 1123-1128. doi: 10.1055/s0030-1270849
  • Köprü, S., Say, R., Karaman, K., Yilmaz, M. M. & Kaplan, M. (2020). Optimization of processing parameters for the preparation of clove (Syzygium aromaticum) hydroalcoholic extract: A response surface methodology approach to characterize the biofunctional performance. Journal of Applied Research on Medicinal and Aromatic Plants, 16, 100236. doi: 10.1016/j.jarmap.2019.100236
  • Ma, T., Wang, Q.H., Wu, H. 2010. Optimization of extraction conditions for improving solubility of peanut protein concentrates by response surface methodology. LWT-Food Science and Technology. 43(9): 1450-1455. doi: 10.1016/j.lwt.2010.03.015
  • Mancini-Filho, J., Van-Koiij, A., Mancini, D. A., Cozzolino, F. F. & Torres, R. P. (1998). Antioxidant activity of cinnamon (Cinnamomum Zeylanicum, Breyne) extracts. Bollettino Chimico Farmaceutico, 137(11), 443-447.
  • Myers, R., Montgomery, D.C. 2002. Response surface methodology: Process and product optimization using designed experiments. 2nd Edition, John Wiley and Sons, New York, USA, 798 s.
  • Seifried, H. E., Anderson, D. E., Fisher, E. I. & Milner, J. A. (2007). A review of the interaction among dietary antioxidants and reactive oxygen species. The Journal of Nutritional Biochemistry, 18(9), 567-579. doi: 10.1016/j.jnutbio.2006.10.007
  • Sheng, Z. L., Wan, P. F., Dong, C. L. & Li, Y. H. (2013). Optimization of total flavonoids content extracted from Flos populi using response surface methodology. Industrial Crops and Products, 43(1), 778-786. doi: 10.1016/j.indcrop.2012.08.020
  • Wang X. S., Wu, Y. F., Chen, G. Y., Yue, W., Liang, Q. L., Wu, Q. N. (2013). Optimization of ultrasound assisted extraction of phenolic compounds from Sparganii rhizoma with response surface methodology. Ultrasonics Sonochemistry, 20(3), 846-854. doi: 10.1016/j.ultsonch.2012.11.007
  • Wijewardhana, U. S., Gunathilaka, U. G. S. & Navaratne, S. B. (2019). Determination of total phenolic content, radical scavenging activity and total antioxidant capacity of cinnamon bark, black cumin seeds and garlic. International Research Journal of Advanced Engineering and Science, 4(2), 55-57.
Yıl 2022, Cilt: 3 Sayı: 2, 58 - 62, 31.12.2022
https://doi.org/10.55147/efse.1218211

Öz

Kaynakça

  • Anderson, R. A., Broadhurst, C. L., Polansky, M. M., Schmidt, W. F., Khan, A., Flanagan, V. P., ... & Graves, D. J. (2004). Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. Journal of Agricultural and Food Chemistry, 52(1), 65-70. doi: 10.1021/jf034916b
  • Bone, K. (2003). A clinical guide to blending liquid herbs: herbal formulations for the individual patient. Elsevier Health Sciences.
  • Çetin, N. (2022). Elma dilimlerinin konvektif kurutulmasinda enerji özelliklerine etki eden faktörlerin yanit yüzeyi yöntemi ile değerlendirilmesi. Bursa Uludağ Üniversitesi Ziraat Fakültesi Dergisi, 36(2), 265-283. doi: 10.20479/bursauludagziraat.1051109
  • Kaplan, M., Yilmaz, M. M., Köprü, S., Gözelle, H., Muhderem, G. & Uslu, R. (2018). Sıvı/katı oranı ve etanol konsantrasyonuna göre karahindiba (Taraxacum officinale) tentürünün verim ve biyoaktivitesindeki değişimin incelenmesi. Türk Tarım ve Doğa Bilimleri Dergisi, 5(2), 163-174. doi: 10.30910/turkjans.421360
  • Karaman, K. & Sagdic, O. (2019). Zygosaccharomyces bailii and Z. rouxii induced ethanol formation in apple juice supplemented with different natural preservatives: A response surface methodology approach. Journal of Microbiological Methods, 163, 105659. doi: 10.1016/j.mimet.2019.105659
  • Koch, E. & Malek, F. A. (2011). Standardized extracts from hawthorn leaves and flowers in the treatment of cardiovascular disorders–preclinical and clinical studies. Planta Medica, 77(11), 1123-1128. doi: 10.1055/s0030-1270849
  • Köprü, S., Say, R., Karaman, K., Yilmaz, M. M. & Kaplan, M. (2020). Optimization of processing parameters for the preparation of clove (Syzygium aromaticum) hydroalcoholic extract: A response surface methodology approach to characterize the biofunctional performance. Journal of Applied Research on Medicinal and Aromatic Plants, 16, 100236. doi: 10.1016/j.jarmap.2019.100236
  • Ma, T., Wang, Q.H., Wu, H. 2010. Optimization of extraction conditions for improving solubility of peanut protein concentrates by response surface methodology. LWT-Food Science and Technology. 43(9): 1450-1455. doi: 10.1016/j.lwt.2010.03.015
  • Mancini-Filho, J., Van-Koiij, A., Mancini, D. A., Cozzolino, F. F. & Torres, R. P. (1998). Antioxidant activity of cinnamon (Cinnamomum Zeylanicum, Breyne) extracts. Bollettino Chimico Farmaceutico, 137(11), 443-447.
  • Myers, R., Montgomery, D.C. 2002. Response surface methodology: Process and product optimization using designed experiments. 2nd Edition, John Wiley and Sons, New York, USA, 798 s.
  • Seifried, H. E., Anderson, D. E., Fisher, E. I. & Milner, J. A. (2007). A review of the interaction among dietary antioxidants and reactive oxygen species. The Journal of Nutritional Biochemistry, 18(9), 567-579. doi: 10.1016/j.jnutbio.2006.10.007
  • Sheng, Z. L., Wan, P. F., Dong, C. L. & Li, Y. H. (2013). Optimization of total flavonoids content extracted from Flos populi using response surface methodology. Industrial Crops and Products, 43(1), 778-786. doi: 10.1016/j.indcrop.2012.08.020
  • Wang X. S., Wu, Y. F., Chen, G. Y., Yue, W., Liang, Q. L., Wu, Q. N. (2013). Optimization of ultrasound assisted extraction of phenolic compounds from Sparganii rhizoma with response surface methodology. Ultrasonics Sonochemistry, 20(3), 846-854. doi: 10.1016/j.ultsonch.2012.11.007
  • Wijewardhana, U. S., Gunathilaka, U. G. S. & Navaratne, S. B. (2019). Determination of total phenolic content, radical scavenging activity and total antioxidant capacity of cinnamon bark, black cumin seeds and garlic. International Research Journal of Advanced Engineering and Science, 4(2), 55-57.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Gıda Mühendisliği
Bölüm Research Articles
Yazarlar

Safa Karaman 0000-0002-1865-661X

Yayımlanma Tarihi 31 Aralık 2022
Gönderilme Tarihi 12 Aralık 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 3 Sayı: 2

Kaynak Göster

APA Karaman, S. (2022). An optimization study for processing variables in fabrication of cinnamon tincture by response surface methodology. European Food Science and Engineering, 3(2), 58-62. https://doi.org/10.55147/efse.1218211