Medicinal Potentials and Health Benefits of Black Mulberry

Yıl 2020, Cilt: 4 Sayı: 1, 1 - 5, 30.08.2020

Muhammad Yasir Naeem

Öz

People
across the globe still use plants as medicinal source due to its easy access
and at low cost availability. Among the genus Morus species Morus nigra (black mulberry) are used in
traditional remedies since ancient time. As they are rich source of a great
variety of various amounts of nutritive and biologically active components like
vitamins, proteins, minerals, anthocyanin, polysaccharides, quercetin etc that
are mainly linked with the  possible
effective pharmacological actions and also play an important role against
various disorders. Moreover, extracts from these fruits also confirmed several
biological activities including antimicrobial activity, anti-Alzheimer’s
activity, anti-tumor and anticancer activity, because of which different
medicinal companies and researchers paying great attention to this plant
fruits. Human research on the medicinal activities of this black mulberry fruit
is limited. Therefore, more study is needed to explicate the compounds present
in it and their possible effect on human health. This review will reveal the
broad spectrum of its medicinal importance, antioxidant potential,
pharmacological uses and the phyto-chemical compositions.

Anahtar Kelimeler

Blackberry, biological activities, human health, and pharmacological actions

Teşekkür

I would like to thanks Assistant Prof. Dr. Senay UGUR for technical support.

Kaynakça

• Ahmed A. Ali M. El-Kholie E. El-Garawani & I. & Sherif N. 2016. Anticancer activity of Morus nigra on human breast cancer cell line (MCF-7): The role of fresh and dry fruit extracts, Journal of Bioscience and Applied Research, 2, 352–361.
• Andallu B. Suryakantham V. Srikanthi B.L., & Reddy G.K. 2001. Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes, Clinica Chimica Acta, 314, 47-53.
• Cao Y. Ma Z.F., Zhang H. Jin Y. Zhang Y. & Hayford F. 2018. Phytochemical properties and nutrigenomic implications of yacon as a potential source of prebiotic: Current evidence and future directions Foods, 7, 59.
• Ercisli S. Orhan E. 2007. Chemical composition of white (Morus alba), red (Morus rubra) and black (Morus nigra) mulberry fruits, Food Chemistry, 103: 1380-1384.
• Fairjuice. 2008. Superfruit mulberry juice. Food and beverage international, 13: 44.
• Gerasopoulos D. Stavroulakis G. 1997. Quality characteristics of four mulberry (Morus spp.) cultivars in the area of Chania Greece, Journal of the Science of Food and Agriculture, 73, 261-264.
• Gryn-Rynko A. Bazylak, G. Olszewska-Slonina D. 2016. New potential phytotherapeutics obtained from whitemulberry (Morus alba L.) leaves, Biomedicine & Pharmacotherapy, 84, 628–636.
• Huang H.P., Chang Y.C., Wu C.H., Hung C.N., Wang C.J. 2011. Anthocyanin-rich Mulberry extract inhibit the gastric cancer cell growth in vitro and xenograft mice by inducing signals of p38/p53 and c-jun, Food Chemistry, 129, 1703–1709.
• Iyengar M.N.S.2007. Research Beliefs. Indian silk, July, 29.
• Kang T.H., Hur J.Y., Kim, H.B., Ryu J.H., Kim S.Y. 2006. Neuroprotective effects of the cyanidin-3-O-beta-D-glucopyranoside isolated from mulberry fruit against cerebral ischemia, Neuroscience Letters, 391, 122–126.
• Koyuncu F. 2004. Morphological and agronomical characterization of native black mulberry (Morus nigra L.) in Sütçüler, Turkey, Plant Genetic Resources Newsletter, 138, 32-35.
• Ma Z.F., Zhang H. 2017. Phytochemical constituents, health benefits, and industrial applications of grape seeds, A mini-review. Antioxidants, 6, 71.
• Mazimba O. Majinda R.R.T., Motlhanka D. 2011. Antioxidant and antibacterial constituents from Morus nigra, African Journal of Pharmacy and Pharmacology, 5, 751–754.
• Naowaboot J. Pannangpetch P. Kukongviriyapan V. Kongyingyoes B. Kukongviriyapan U. 2009. Antihyperglycemic, antioxidant and antiglycation activities of mulberry leaf extract in streptozotocin-induced chronic diabetic rats, Plant Foods for Human Nutrition, 64, 116-121.
• Natic M.M., Dabic D.C., Papetti A. Fotiric. Akšic M.M., Ognjanov V. Ljubojevic M. Tešic Ž. 2014. Analysis and characterisation of phytochemicals in mulberry (Morus alba L.) fruits grown in Vojvodina, North Serbia, Food Chemistry, 171, 128–136.
• Nishizawa T. Suzuki H. 2015. Gastric carcinogenesis and underlying molecular mechanisms: Helicobacter pylori and novel targeted therapy, BioMed Research International, 794378.
• Sánchez-Salcedo E.M., Sendra E. Carbonell-Barrachina Á.A., Martínez J.J., Hernández F. 2016. Fatty acids composition of Spanish black (Morus nigra L.) and white (Morus alba L.) mulberries, Food Chemistry, 190, 566–571.
• Singhal B.K., Khan M.A., Dhar A. Baqual F.M., Bindroo B.B. 2018. Approaches to industrial exploitation of mulberry (Morus sp.) fruits, Journal of Fruit and Ornamental Plant Research, 18(1), 83-99.
• Song W. Wang H.J., Bucheli P. Zhang P.F., Wei D.Z., Lu Y.H. 2010 Phytochemical profiles of different mulberry (Morus) species from China, Journal of Nutritional Biochemistry, 21(7), 598-605.
• Tahir L. Aslam A. Ahmed S. 2017. Antibacterial activities of Diospyros blancoi, Phoenix dactylifera and Morus nigra against dental caries causing pathogens: An in vitro study, Pakistan Journal of Pharmaceutical Sciences, 30, 163–169.
• Thaipitakwong T. Numhom S. Aramwit P. 2018. Mulberry leaves and their potential effects against cardiometabolic risks: A review of chemical compositions, biological properties and clinical efficacy, Pharmaceutical Biology, 56, 109–118.
• Veeresham C. 2012. Natural products derived from plants as a source of drugs, Journal of Advanced Pharmaceutical Technology & Research, 3,200–201.
• Vijayan K. Chauhan S. Das N.K., Chakraborti S.P., Roy B.N. 1997. Leaf yield component combining abilities in mulberry (Morus spp.), Euphytica, 98, 47–52.
• Yaltirik F. 1982. Morus. In: Davis, P.H. (ed.), Flora of Turkey, 641-642. Edinburgh University Press, Edinburgh, 641-642.
• Zou S. & Chen Wu. 2003. A review on chemical constituents, pharmacological activity and application of mulberry leaves, Journal of Forest Products and Industries, 1: 22-25.