Ocular Surface Findings in Chronic Renal Failure

Abstract

The purpose of this study was to describe the ocular surface findings in chronic renal failure (CRF). Sixty eyes of 30 patients with CRF group and 70 eyes of 35 healthy subjects were evaluated. Schirmer-I, tear film break-up time tests and conjunctival impression cytology were performed in addition to complete ophthalmologic examination. The presence of dry eye symptoms and conjunctival calcification were noted. The groups were age and gender matched. The mean break-up time was 10.3±3.1 in group-1 and 11.2±1.7 seconds in the group-2 (p=0.03). The mean Schirmer score was 11.2±2.8 mm and 12.0±1.7 mm in the CRF and control group (p=0.095), respectively. In CRF group, conjunctival impression cytology was revealed as grade-0 findings in 16 eyes, grade 1 findings in 41 eyes and grade 2 findings in 3 eyes, in control group, it was revealed grade-0 findings in 48 eyes, grade 1 findings in 22 eyes and showed no changed in grade 2 (p

Keywords

• Calcification, chronic renal failure, impression cytology, lissamine

Ocular Surface Findings in Chronic Renal Failure

Öz

Çalışmamızdaki amacımız kronik böbrek yetmezliği (KBY)’nde oküler yüzey bulgularını tanımlamaktır. KBY bulunan 30 hastanın 60 gözü ve sağlıklı 35 olgunun 70 gözü değerlendirildi. Tam bir oftalmolojik muayenenin yanında Schirmer I testi, göz yaşı kırılma zamanı ve konjunktival impresyon sitolojisi yapıldı. Konjunktival kalsifikasyon ve kuru göz bulguları kaydedildi. Gruplar yaş ve cinsiyet uyumlu idi. Ortalama göz yaşı kırılma zamanı KBY grubunda 10.3±3.1 ve kontrol grubunda 11.2±1.7 saniye idi (p=0.03). Schirmer skoru KBY grubunda 11.2±2.8 ve kontrol grubunda 12.0±1.7 mm olarak ölçüldü (p=0.095). İmpresyon sitolojisi bulguları KBY grubunda 16 gözde grade 0, 41 gözde grade 1 ve 3 gözde grade 2 iken kontrol grubunda 48 gözde grade 0, 22 gözde grade 1 olarak izlendi (p<0.001). Konjunktival kalsifikasyon değişimleri KBY grubunda 18 gözde grade 0, 34 gözde grade 1 ve 8 gözde grade 2 iken kontrol grubunda tüm olgular grade 0 olarak tespit edildi (p<0.001). Kaşıntı (%45), kızarıklık (%95) ve yabancı cisim hissi (%83) KBY grubunda konjunktival kalsifikasyon olan olgularda daha sık olarak görüldü (p<0.001). Kronik böbrek yetmezliğinde göz yaşı üretimi normal olmasına rağmen kalsifikasyonlar ve göz yaşı kalitesinin bozulmasına bağlı olarak normal bireylere göre oküler yüzey şikayetleri daha fazla olmaktadır

Anahtar Kelimeler

• İmpresyon sitolojisi, kalsifikasyon, kronik böbrek yetmezliği, lisamin

Kaynakça

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