Solitary Fibrous Tumor of the Pleura

Abstract

Solitary fibrous tumor is a rare mesenchymal malignancy that may be found in many locations other than the pleura. The majority of these tumors have benign features, but some have malignant potential. We report a histologically proven case of a solitary fibrous tumor in a 52-year-old woman that was incidentally detected by chest radiography during a routine health check. Left posterolateral thoracotomy was performed and then the mass was completely removed. His postoperative recovery was uneventful.

Keywords

• Pleura, solitary fibrous tumor, dyspnea

Solitary Fibrous Tumor of the Pleura

Öz

Soliter fibröz tümör, nadir bir mezenkimal tümördür ve plevradan başka birçok lokalizasyonda bulunabilir. Bu tümörlerin büyük kısmı bening özelliklere sahiptir fakat bazılarında malign potansiyel olabilir. Biz, 52 yaşında bayan hastada, rutin sağlık kontrolleri sırasında akciğer grafisi ile tesbit edilen ve histolojik olarak ispatlanan soliter fibröz tümör olgusunu sunuyoruz. Sol lateral torakotomi yapıldıktan sonra kitle total olarak çıkarıldı. Postoperatif dönem sorunsuzdu

Anahtar Kelimeler

• Plevra, soliter fibröz tümör, dispne

Kaynakça

1. Baliga M, Flowers R, Heard K, Siddiqi A, Akhtar I. Solitary Fibrous Tumor of the Lung: A Case Report With a Study of the Aspiration Biopsy, Histopathology, Immunohistochemistry, and Autopsy Findings. Diagnostic Cytopathology 2006;35(4):239-44
2. Kanamori Y, Hashizume K, Sugiyama M, et al. Intrapulmonary Solitary Fibrous Tumor in an Eight-Year- Old Male. Pediatr Pulmonol 2005; 40:261–4.
3. Maeda S, Sugita M, Sagawa M, MD, Ueda Y, Sakuma T. Solitary Fibrous Tumor of the Pleura Suddenly Induced Hypoglycemia before Surgical Treatment Ann Thorac Cardiovasc Surg 2011; 17: 293–6
4. Weiss SW, Nickoloff BJ. CD34 is expressed by a distinctive cell population in peripheral nerve, nerve sheath tumors, and related lesions. Am J Surg Pathol 1993;17:747–53.
5. Nickoloff J. The human progenitor cell antigen (CD34) is localized on endothelial cells, dermal dendritic cells, and perifollicular cells in formalin-fixed normal skin, and on proliferating endothelial cells and stromal spindle shaped cells in Kaposi’s sarcoma. Arch Dermatol 1991;127:523–9.
6. Briselli M, Mark EJ, Dickersin GR. Solitary fibrous tumors of the pleura: eight new cases and review of 360 cases in the literature. Cancer 1981; 47: 2678-89.
7. England DM, Hochholzer L, McCarthy MJ. Localized be- nign and malignant fibrous tumors of the pleura. A clini- copathologic review of 223 cases. Am J Surg Pathol 1989; 13: 640-58.
8. Kohler M, Clarenbach CF, Kestenholz P, et al. Diagnosis, treatment and long-term outcome of solitary fibrous tumours of the pleura. Eur J Cardiothorac Surg 2007; 32:403-8.

9. Klemperer P, Rabin CB. Primary neoplasms of the pleura. Arch Pathol 1931;11:385–412.
10. De Perrot M, Fisher S, Brundler MA, Sekine Y, Keshavjee S. Solitary fibrous tumors of the pleura. Ann Thorac Surg 2002;74:285–93.
11. Kouki E, Dougenis D. Solitary fibrous tumor of the lung. Gen Thorac Cardiovasc Surg 2008;56:249-51
12. Robinson LA. Solitary Fibrous Tumor of the Pleura. Cancer Control 2006; 13(4): 264-9
13. Cardillo G, Carbone L, Carleo F,et al. Solitary fibrous tu- mors of the pleura: an analysis of 110 patients treated in a single institution. Ann Thorac Surg 2009; 88: 1632-7.