A Rare Mediastinal Tumor: Thymolipoma

Abstract

Thymolipoma is a rare benign tumor of mediastinum. It comprises 2-9% of all thymic neoplasms. A 35-year-old man patient applied to our hospital with chest pain. In physical examination nothing characteristic was found and the routine laboratory findings were not remarkable. A chest radiograph showed no abnormalities however chest multislice computed tomography scans revealed an anterior mediastinal lesion in thymic area. No findings was found in respect of invasion in magnetic resonance imaging. Preoperatively radiological diagnosis was thymic hyperplasia but histopathological diagnosis was thymolipoma. We present the case of thymolipoma phenomenon which causes the chest pain.

Keywords

• Thymolipoma, mediastinal tumor, thymic hyperplasia

A Rare Mediastinal Tumor: Thymolipoma

Öz

Timolipoma mediastenin nadir benign tümörüdür. Timolipoma tüm timik neoplazilerin 2-9%’ unu oluşturur. Otuzbeş yaşında erkek hasta, göğüs ağrısı ile hastanemize başvurdu. Fizik muayenede özellik yoktu. Laboratuar bulguları normal sınırlarda idi Göğüs radyografisinde anormallik görülmedi ancak göğüs bilgisayarlı tomografisinde timik bölgede anterior mediastinal lezyon tespit edildi. Magnetic resonance görüntülemesinde invazyon açısından bulgu saptanmadı. Operasyon öncesi radyolojik tanı timik hiperplaziydi ancak histopatolojik tanı timolipomaydı. Biz burada göğüs ağrısına sebep olan nadir bir timolipoma olgusunu sunuyoruz

Anahtar Kelimeler

• Timolipoma, mediastinal tümör, timik hiperplazi

Kaynakça

1. Mourad OM, Andrade FM, Abrahão P, Monnerat A, Judice LF. Asymptomatic giant mediastinal mass: a rare case of thymolipoma. J Bras Pneumol 2009;35(10):1049-52.
2. Teplick JG, Nedwich A, Haskin ME. Roentgenographic Features of thymolipoma. Am J Roentgenol Radium Ther Nucl Med 1973; 117: 873–80.
3. Gamondes JP, Balawi A, Greenland T. Seventeen years of surgical treatment of thymoma: factors influencing sur- vival. Eur J Cardiothorac Surg 1991;5:124-31.
4. Hirai S, Hamanaka Y, Mitsui N, Kumegai H, Kobayashi T. Gigantic thymolipoma. Jpn J Thorac Cardiovasc Surg 2002; 50: 40–2.
5. Nishimura O, Naito Y, Noguchi Y, Matsuoka S, Takanaka K. Thymolipoma: a report of three cases. Jpn J Surg 1990; 20: 234–7.
6. Wang Y, Sun Y, Zhang J, et al. Diagnosis, treatment and prognosis of thymoma: an analysis of 116 cases. Chin Med J 2003;116(8):1187-90.
7. Roque C, Rodríguez P, Quintero C, Santana N, Hussein M, Freixinet J. Giant thymolipoma [Article in Spanish]. Arch Bronconeumol 2005;41(7):402-3.
8. Scully NM. Lipothymoma with cystic lymphangioma. Am Surg 1960;26: 400-4.

9. Argani P, Rosai J. Thymoma arising with a thymolipoma. Histopathology 1998;32: 5568-78.