Destroyed Lung Secondary to Multiple Myeloma in a Previously Treated Tuberculosis Patient

Yıl 2014, , - , 21.03.2016

Ali Kutlucan Leyla Yilmaz Aydin İbak Gonen Havva Erdem Mustafa Ozsahin Yusuf Aydin Leyla Kutlucan Mehmet Turgut Ramazan Buyukkaya

https://doi.org/10.15197/sabad.1.11.30

Öz

This case is presented with a pulmonary parenchymal destruction due to acquired multiple myeloma who has a history of pulmonary tuberculosis. A 55 year old male patient attempted to emergency department with complaints of shortness of breath. The final diagnose with the existing clinical and laboratory outputs were right pulmonary parenchymal destruction and pleural involvements secondary to multiple myeloma. Our prediagnose was confirmed by the overt plasma cell increase and Russell bodies in cytopathologic examination of the pleural fluid. Even though multiple myeloma leads to destruction in the pulmonary parenchyma rarely, patients should be scrutinized enough to elicit true diagnose.

Anahtar Kelimeler

Multiple myeloma, tuberculosis, destroyed lung

Destroyed Lung Secondary to Multiple Myeloma in a Previously Treated Tuberculosis Patient

Öz

Multipl myeloma bağlı, pulmoner parankimal destrüksiyon gelişen, daha önceden geçirilmiş pulmoner tüberküloz öyküsü olan vaka sunulmuştur. 55 yaşında erkek hasta acil servise nefes darlığı şikayeti ile başvurdu. Hasta klinik bulguları ve labaratuar tetkikleri ile değerlendirildikten sonra, mutipl myeloma sekonder sağ pulmoner parankimal destrüksiyon ve plevral tutulum tanısı konuldu. Ön tanımız, plevral sıvının sitopatolojik incelemesinde artmış plazma hücresi ve Russell body hücreleri görülmesi ile doğrulandı. Multipl myelom nadiren pulmoner parankimal destrüksiyone yol açmasına rağmen, hastalarda ayırıcı tanı için ayrıntılı incelemek gerekmektedir

Anahtar Kelimeler

Mutipl myelom, tüberküloz, akciğer destrüksiyonu

Kaynakça

• Kyle RA, Rajkumar SV. Multiple myeloma. Cecil Textbook of Medicine. 22nd ed. Philadelphia. Saunders. 2004; pp 1184-95.
• Suchman AL, Coleman M, Mouradian JA, Wolf DJ, Saletan S. Aggressive plasma cell myeloma: a terminal phase. Arch Intern Med 1981;141:1315-20.
• Shin MS, Carcelen MF, Ho KJ. Diverse roentgenographic manifestations of the rare pulmonary involvement in my- eloma. Chest 1992;102:946-8.
• Palmer HE, Wilson CS, Bardales RH. Cytology and flow cytometry of malignant effusions of multiple myeloma. Diagn Cytopathol 2001;22:147-51.
• Kintzer JS, Rosenow EC, Kyle RA. Thoracic and pulmo- nary abnormalities in multiple myeloma. Arch Intern Med 1978;138:727-30.
• Schelle M, Schreiber C, Knolle J, Florschütz A, Kachel R, Schreiber J. Pulmonary and pleural manifestations of multiple myeloma. Pneumologie 2006;60(12):743-8.
• Kamble R, Rosenzweig T. Diffuse pulmonary parenchymal involvement in multiple myeloma: antemortem diagno- sis. Int J Hematol 2006;83(3):259-61.
• Marmor DB, Farber JL, Gottlieb JE. Acute respiratory 47
• Obuekwe ON, Nwizu NN, Ojo MA, Ugbodaga PI. Extramedullary presentation of multiple myeloma in the parotid gland as first evidence of the disease a review with case report. Niger Postgrad Med J 2005;12:45-8.