Angiomyolipoma of the Uterus

Abstract

Angiomyolipoma (AML) is a mesenchymal neoplasm composed of a variable mixture of adipose tissue, smooth muscle cells, and anomalous blood vessels. In the uterus, only a few cases have been reported. We described a uterine AML without evidence of tuberous sclerosus (TS). The clinical presentations of uterine angiomyomatous lesions are nonspecific. The diagnosis of angiomyolipoma can be established with ultrasound and/or computed tomography (CT). The patients whose lower abdomen mass in the abdominopelvic ultrasound and dysfunctional uterine bleeding should be considered AML in the differential diagnosis.

Keywords

• Angiomyolipoma, uterus, mesenchymal neoplasm

Angiomyolipoma of the Uterus

Öz

Anjiyomiyolipom (AML) yağ dokusu, düz kas hücreleri ve anormal kan damarlarının değişken karışımından oluşan bir mezenkimal tümördür. Uterusta, sadece birkaç vaka bildirilmiştir. Biz tuberoz skleroz (TS) olmadan bir uterin AML tanımladık. Uterus anjiomiyomatöz lezyonların kliniği spesifik değildir. Anjiyomiyolipom tanısı ultrasonografik ve / veya bilgisayarlı tomografi (BT) ile konulabilir. Abdominopelvik ultrasonda alt karında kitle ve disfonksiyonel uterin kanaması olan hastaların ayırıcı tanısında AML dikkate alınmalıdır

Anahtar Kelimeler

• Anjiyomiyolipom, uterus, mezankimal tümör

Kaynakça

1. Hornick JL, Fletcher CDM. Pecoma: what do we know so far? Histopathology 2006; 48: 75-82.
2. Fadare O. Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasm. Int Semin Surg Oncol 2008; 5: 7.
3. Yaegashi H, Moriya T, Soeda S, Yonemoto Y, Nagura H and Sasano H. Uterine angiomyolipoma: case report and re- view of the literature. Pathol Int 2001; 51: 896-901.
4. Huang PC, Chen JT, Ho WL. Clinicopathologic analysis of renal and extrarenal angiomyolipomas: report of 44 cas- es. Chinese Med J 2000; 63: 37-44.
5. Tamboli P, Ro JY, Amin MB, Ayala AG. Benign tumors and tumor-like lesions of the adult kidney. Part II. Benign mesenchymal and mixed neoplasms, and tumor-like le- sions. Adv Anat Pathol 2000; 7: 47-66.
6. Simmons JL, Hussain SA, Riley P, Wallace DM. Management of renal angiomyolipoma in patients with tuberous scle- rosis complex. Oncol Rep 2003; 10: 237-41.
7. Ren RL, Wu HH. Pathologic quiz case: a 40-year-old wom- an with an unusual uterine tumor. Uterine angiolipoleio- myoma with focal atypical leiomyoma. Arch Pathol Lab Med 2004, 128: e31-2.
8. Daraï E, Bazot M, Barranger E, Detchev R, Cortez A. Epithelioid angiomyolipoma of the uterus: a case report. J Reprod Med 2004; 49: 578-81.

9. Cil AP, Haberal A, Hucumenoglu S, Kovalak EE, Gunes M. Angiomyolipoma of the uterus associated with tuber- ous sclerosis: case report and review of the literature. Gynecol Oncol 2004; 94: 593-6.
10. Gyimadu AO, Kara O, Basaran D, Esinler I. Conservative management of a retroperitoneal hemorrhage following a ruptured renal angiomyolipoma in pregnancy. J Obstet Gynaecol Res 2011; 37: 156-9. 180