Adjuvant Radiotherapy for Male Breast Carcinoma

Abstract

Breast cancer accounts for 0.2%-1.5% of all malignant tumors in males and 1% of all breast cancers. Unfortunately, to date, almost all data concerning its treatment and prognostic factors have been obtained from epidemiological and clinical studies involving only females, although the incidence of male breast cancer is increasing. Herein, we present male breast cancer patients at our center. This study included 10 consecutive male patients with a diagnosis of breast cancer. All the patients were treated between January 2002 and February 2010. The median age of the patients was 69.5 years (range: 57-85 years) at presentation, and all underwent surgical treatment. Two of the patients were not given chemotherapy, one because of bone metastasis and the other due to advanced age. Curative radiotherapy was performed in all but 1 of the patients. Median follow-up was 36 months (range: 7-77 months). Although prognostic factors in male breast cancer patients are similar to those in females, and early diagnosis and use of adjuvant treatment (radiotherapy, hormone therapy, and chemotherapy) decreases the rate of local recurrence and increases survival similarly as in females, additional research is necessary for determining the optimal treatment strategy for this disease in males. Key words: Male, breast cancer, adjuvant radiotherapy Erkek

Keywords

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Adjuvant Radiotherapy for Male Breast Carcinoma

Öz

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Anahtar Kelimeler

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Kaynakça

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8. ERS; Estrogen Receptor Status, PRS; Progesterone Receptor Status IDC: Infiltrating ductal carcinoma, LRM: Left radical mastectomy, RRM: Right radical mastectomy, CEF: Cyclophosphamide, epirubicin, fluorouracil, T: Tamoxifen, D: Docataxel, CE: Cyclophosphamide, epirubicin, CA: Cyclophosphamide, adriamycin, CAF: Cyclophos- phamide, adriamycin, fluorouracil