A CASE OF TYPHOID FEVER PRESENTING WITH MULTIPLE COMPLICATIONS

Öz

-

Anahtar Kelimeler

• -

A CASE OF TYPHOID FEVER PRESENTING WITH MULTIPLE COMPLICATIONS

Öz

An 18- year old female patient was admitted to the Emergency Department with complaints of fever and fatigue beginning 15 days ago associated with headache, weakness, palpitation, abdominal pain, and diarrhea a week later. The patient who apathic confused and discordant was transferred to the Department of Infectious Diseases. There was also hypocalcemia, hypopotassemia, pancytopenia, intestinal hemorrhage, and hepatic involvement. S. typhi was grown in the blood culture. The patient was discharged with full recovery after ciprofloxacin treatment in addition to electrolyte replacement. Typhoid fever is a widespread infectious disease in our country and should be taken into consideration in differential diagnosis of many diseases because it may involve a number of systems and may present with a variety of complications

Anahtar Kelimeler

• Salmonella, salmonellosis, typhoid fever, hypocalcemia, hypopotassemia, pancytopenia, intestinal hemorrhage, and hepatitis

Kaynakça

1. Miller SI, Pegues DA. Salmonella Species, Including Salmonella typhi. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 5th ed. Philadelphia: Churchill Livingstone, 2000:2344-56
2. Parry CM, Hien TT, Dougan G, White NJ, Farrar JJ. Typhoid Fever. N Engl J Med 2002;347:1770-82
3. Topçu AW. Typhi and non-typhi salmonellosis. In: Topçu AW, Söyletir G, Doğanay M, eds. Infectious Diseases and mycrobiology. Nobel Medical Book 2002:642-53
4. Gilman RH, Terminel M, Levine MM, Hernandez-Mendoza P, Hornick RB. Relative efficacy of blood, urine, rectal swab, bone marrow, and rose-spot cultures for recovery of Salmonella typhi in typhoid fever. Lancet 1975;1:1211-13
5. Willke A, Ergönül Ö, and Bayar B. Widal Test in Diagnosis of Typhoid Fever in Turkey. Clinical and Diagnostic Laboratory Immunology 2002;9:938–41
6. Butler T, Islam A, Kabir I, Jones PK. Patterns of morbidity and mortality in typhoid fever dependent on age and gender: a review of 552 hospitalized patients with diarrhea. Rev Infect Dis 1991;13:85-90
7. Chambers HF. Infectious Diseases: Bacterial and Chlamydial. In: Tierney LM, McPhee SJ, Papadakis MA, eds. Current Medical Diagnosis and Treatment. 37th ed. London: Prentice Hall International Inc, 1998:1267-303
8. Bitar RE, Tarpley J. Intestinal perforation in typhoid fever: a historical and state- of-the-art review. Rev Infect Dis 1985; 7: 257-71

9. Van Basten JP, Stockenbrugger R. Typhoid perforation: a review of the literature since 1960. Trop Geogr Med 1994;46:336-39
10. Hoşoglu S, Aldemir M, Akalın Ş, Geyik MF, Taçyıldız IH, Loeb M. Risk Factors for Enteric Perforation in Patients with Typhoid Fever. Am J Epidemiol 2004; 160:46-50
11. Nguyen QC, Everest P, Tran TK, et al. A clinical, microbiological, and pathological study of intestinal perforation associated with typhoid fever. Clin Infect Dis 2004; 39:61-7
12. Özen H, Seçmeer G, Kanra G, et al: Typhoid fever with very high transaminase levels. Turk J Pediatr 1995; 37:169-71
13. Kundu AK. Typhoid hepatitis. J Assoc Physicians India 2002;50:719-20
14. Mert A, Tabak F, Özaras R, Özturk R, Akı H, Aktuğlu Y. Typhoid fever as a rare cause of hepatic, splenic, and bone marrow granulomas. Intern Med 2004; 43:436-9
15. Pearson RD, Guerrant RL. Enteric fever and other causes of abdominal symptoms with fever. In: Principles and Practice of Infectious Disease. Mandell GL, Bennett JE, Dolin R, eds. 5th ed. Philadelphia: Churchill Livingstone, 2000:1136-40
16. Khosla SN, Anand A, Singh U, Khosla A. Haematologic profile in typhoid fever. Trop Doct 1995;25:156-58
17. Jemni L, Mehdi A, Chakroun M, Chatti N, Djaidane A. Complications of typhoid fever. Med Trop 1989;49:189-91
18. Ramanan A, Pandit N, Yeshwanth M. Unusual complications in a multidrug resistant Salmonella typhi outbreak. Indian Pediatr 1992;29:118-20
19. Ali G, Rashid S, Kamli MA, Shah PA, Allaqaband GQ. Spectrum of neuropsychiatric complications in 791 cases of typhoid fever. Trop Med Int Health 1997;2:314-18
20. Lin FY, Ho VA, Bay PV, et al. The epidemiology of typhoid fever in the Dong Thap Province, Mekong Delta region of Vietnam. Am J Trop Med Hyg 2000;62:644-8