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SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES
Öz
Aim: Angiogenesis is an important factor in tumoral progression, metastasis and invasion. More recently, it has also been found to play a particular role in hematological malignancies. Methods: In this study, 45 patients harboring hematological malignancies (15 acute myeloid leukemia (AML), 10 acute lymphoblastic leukemia (ALL), 10 multiple myeloma (MM), 10 chronic myeloid leukemia (CML)) were compared with 20 healthy individuals matched according to age and sex, regarding serum vascular endothelial growth factor (VEGF, a marker for angiogenesis) levels. Results: The difference between serum VEGF levels of the study group (338.4 ± 587.6 pg/mL) and the control group (69.9 ± 24.4 pg/mL) was statistically significant (p
Anahtar Kelimeler
Kaynakça
- Folkman J, Shing Y. Angiogenesis. J Biol Chem 1992;267:10931–34
- Folkman J. Clinical applications of research on angiogenesis. N Eng J Med 1995;333:1757-63
- Perez-Atayde AR, Sallan SE, Tedrow U, et al. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. Am J Pathol 1997;150:815-21
- Ribatti D, Vacca RD, Nico B, et al. Angiogenesis spectrum in the stroma of B-cell non-Hodgkin’s lymphomas. An immunohistochemical and ultrastructural study. Eur J Haematol 1996;56:45-53
- Padro T, Ruiz S, Bieker R, et al. Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia. Blood 2000;95:2637-44
- Vacca A, Ribatti D, Presta M, et al. Bone marrow neovascularization, plasma cell angiogenic potential, and matrix metalloproteinase-2 secretion parallel progression of human multiple myeloma. Blood 1999;93:3064-73
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Ayrıntılar
Birincil Dil
İngilizce
Konular
-
Bölüm
-
Yayımlanma Tarihi
1 Eylül 2006
Gönderilme Tarihi
27 Nisan 2015
Kabul Tarihi
-
Yayımlandığı Sayı
Yıl 2006 Cilt: 3 Sayı: 3
APA
Erdem, F., Gündogdu, M., & Kiziltunç, A. (2006). SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES. European Journal of General Medicine, 3(3), 116-120. https://izlik.org/JA24FT85YJ
AMA
1.Erdem F, Gündogdu M, Kiziltunç A. SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES. European Journal of General Medicine. 2006;3(3):116-120. https://izlik.org/JA24FT85YJ
Chicago
Erdem, Fuat, Mehmet Gündogdu, ve Ahmet Kiziltunç. 2006. “SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES”. European Journal of General Medicine 3 (3): 116-20. https://izlik.org/JA24FT85YJ.
EndNote
Erdem F, Gündogdu M, Kiziltunç A (01 Eylül 2006) SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES. European Journal of General Medicine 3 3 116–120.
IEEE
[1]F. Erdem, M. Gündogdu, ve A. Kiziltunç, “SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES”, European Journal of General Medicine, c. 3, sy 3, ss. 116–120, Eyl. 2006, [çevrimiçi]. Erişim adresi: https://izlik.org/JA24FT85YJ
ISNAD
Erdem, Fuat - Gündogdu, Mehmet - Kiziltunç, Ahmet. “SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES”. European Journal of General Medicine 3/3 (01 Eylül 2006): 116-120. https://izlik.org/JA24FT85YJ.
JAMA
1.Erdem F, Gündogdu M, Kiziltunç A. SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES. European Journal of General Medicine. 2006;3:116–120.
MLA
Erdem, Fuat, vd. “SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES”. European Journal of General Medicine, c. 3, sy 3, Eylül 2006, ss. 116-20, https://izlik.org/JA24FT85YJ.
Vancouver
1.Fuat Erdem, Mehmet Gündogdu, Ahmet Kiziltunç. SERUM VASCULAR ENDOTHELIAL GROWTH FACTOR LEVEL IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES. European Journal of General Medicine [Internet]. 01 Eylül 2006;3(3):116-20. Erişim adresi: https://izlik.org/JA24FT85YJ