HYPOCALCEMIA INDUCED RHABDOMYOLYSIS AND ACUTE RENAL FAILURE AFTER THYROIDECTOMY: A CASE REPORT

Öz

-

Anahtar Kelimeler

• -

HYPOCALCEMIA INDUCED RHABDOMYOLYSIS AND ACUTE RENAL FAILURE AFTER THYROIDECTOMY: A CASE REPORT

Öz

Rhabdomyolysis is a potentially life-threatening syndrome resulting from the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. We report a case of a 24-year-old woman with hypocalcemia which occured after a thyroidectomy operation. This hypocalcemia was severe enough to cause convulsion, rhabdomyolysis and acute renal failure. The reason of severe hypocalcemia in our case may be multifactorial; hypoparathyroidism, rhabdomyolysis and acute renal failure. The development of hypocalcemia, convulsion attacks, rhabdomyolysis and acute renal failure occurring in the patient after iatrogenic hypoparathyroidism has rendered the case interesting due to the rarity of such developments. Key words: Acute renal failure, convulsions, hypocalcemia, iatrogenic hypoparathyroidism, rhabdomyolysis.

Anahtar Kelimeler

• Acute renal failure, convulsions, hypocalcemia, iatrogenic hypoparathyroidism, rhabdomyolysis

Kaynakça

1. Pattou F, Combemale F, Fabre S et al. Hypocalcemia following thyroid surgery: incidence and prediction of outcome. World J Surg 1998;22:718-24
2. Akmal M. Rhabdomyolysis in a patient with hypocalcemia due to hypoparathyroidism. Am J Nephrol 1993;13:61-3
3. Warren JD, Blumbergs PC, Thompson PD. Rhabdomyolysis: a review. Muscle Nevre 2002;25:332-47
4. Akmal M, Bishop JE, Telfer N, Norman AW, and hypercalcemia in patients with rhabdomyolysis with and without acute renal failure. J Clin Endocrinol Metab 1986;63:137-42 Hypocalcemia
5. Woodrow G, Brownjohn AM, Turney JH. The clinical and biochemical features of acute renal failure due to rhabdomyolysis. Ren Fail 1995;17:467-74
6. Llach F, Felsenfeld AJ, Haussler MR. The pathophysiology of altered calcium metabolism induced Interactions of parathyroid hormone, 25-hydroxycholecalciferol, and 1,25- dihydroxycholecalciferol. N Engl J Med 1981;305:117-23
7. rhabdomyolysis- renal acute failure.
8. Motellon JL, Bernis C, Gruss E, Traver JA. Role of parathyroid hormone and 1,25 dihydroxycholecalciferol in calcium homeostasis of rhabdomyolysis. Nephrol. Dial. Transplant 1995;10:299-300

9. Shrestha SM, Berry JL, Davies M, Ballardie FW. Biphasic hypercalcemia in severe rhabdomyolysis: serial analysis of PTH and vitamin D metabolites. A case report and literature review. Am J Kidney Dis 2004;43:31-5