BibTex RIS Kaynak Göster

Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India

Yıl 2013, Cilt: 10 Sayı: 3, 150 - 153, 01.09.2013

Öz

Onychomycosis is a major public health problem with high incidence, associated morbidity and long lasting treatment with anti-fungal agents. This study was carried out to know the clinico-mycological pattern of onychomycosis which can help in the control of this infection. The aim of this study was to determine the prevalence of various causative agents of onychomycosis, to identify the clinical pattern and to analyze the risk factors. This was a prospective study carried over a period of one year from Ist February 2010 to 31st january 2011 on samples from 150 patients with clinically suspected nail infections attending the dermatology department of SKIMS Medical college, Kashmir. The nails were evaluated clinically and the nail samples were subjected to direct microscopy and culture. 66.6% samples were positive by direct microscopy and culture. Males were infected more than females. The commonest age group infected was 21-30 years. Finger nails were affected more frequently than toe nails and distolateral subungal onychomycosis was the most common clinical type seen in 66% patients. The etiological agents were dermatophytes (62.68%), NDM (29.85%), yeasts (7.46%). Among dermatophytes T. rubrum was the commonest etiological agent.

Kaynakça

  • Kaur R, Kashyap P, Bhalla P. Onychomycosis-epidemiology, diagnosis and management. Indian J Med Microbiol 2008; 26(2): 108-16.
  • Scher P; Onychomycosis a significant medical disorder. J Am Acad Dermatol 1996; 35: S2-5.
  • Midgley G, Moore MK: Nail infections. Dermatol Clin 1996; 14: 41-9.
  • Williams HC. The epidemiology of onychomycosis in Britain. Br J Dermatol 1993; 129:101-9.
  • Odom RB. Common superficial fungal infections in im- munosuppressed patients. J Am Acad Dermatol 1994; 31: 556-9
  • Shenoy MM, Teerthnath S, Karnaker VK, Girisha BS, Krishna Prasad MS, Pinto J. Comparison of potassium hy- droxide mount and mycological culture with histopatho- logic examination using periodic acid-shiff staining of nail clippings in the diagnosis of onychomycosis. Indian J Dermatolol Veneorol Leprol 2008; 74:226-9.
  • Kaur R, Kashyap B, Bhalla P. A five year survey of onycho- mycosisin New Delhi, India: epidemiological and labora- tory aspects. Indian J Dermatolol 2007; 52: 39- 42.
  • Winberg JM, Koestenblatt EK, Turtone WD, Tishler HR. Najarian L. Comparison of diagnostic methods in the evaluation of onychomycosis. J Am Acad Dermatol 2003; 49(2) 193-7.
  • Alvarez MI, Gonzalez LA, Castro LA. Onychomycosis in Cali, Colombia. Mycopathologia 2004; 158: 181-6.
  • Garg A, Venkatesh V, Singh M, Pathak KP. Onychomycosis in Central India: a clinico etiological correlation. Int J Dermatol 2004; 43(7): 498-502.
  • Adhikari L, Gupta AD, Pal R, Singh T. Clinico-etiologic co-relates of onychomycosis in Sikkim. Indian J Pathol Microbiol; 52: 194-7.
  • Grover S. Clinico-mycological evaluation of onychomyco- sis at Banglore and Jorhat. Indian J Dermatolol Veneorol Leprol 2003; 69: 284-6.
  • Aghamirian MR, Ghiasian SA. Onychomycosis in Iran: epi- demiology, causative agents and clinical features. Jpn J Med Mycol 2010; 51: 23-9.
  • El Sayed F, Ammoury A,Haybe RF, Daybi R: Onychomycosis in Lebanon: a mycological survey of 772 patients. Mycoses 2006; 49:216-9.
  • Gupta AK, Jain HC, Lynde CW, Macdonald P, Cooper EA, Summerbell RC. Prevalence and epidemiology of onycho- mysis in patients visiting physicians offices: A multicentre Canadian survey of 15000 patients. J Am Acad Dermatol 2000; 43: 244-8.
  • Koursidou T, Devliotou Panagiotidou D, Karakatsanis G, Minas A, Mourellou O, Samara K. Onychomycosis in Northern Greece during 1994-98. Mycoses 2002; 45: 29- 37.
  • Veer P, Patwardhan NS, Damle AS. Study of 56.Onychomycosis: prevailing fungi and pattern of infec- tion. Indian J Med Microbiol 2007; 25: 53-6

Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India

Yıl 2013, Cilt: 10 Sayı: 3, 150 - 153, 01.09.2013

Öz

Onikomikozler yüksek insidans ile birlikte morbidite ve anti-fungal ajanlar ile uzun süren tedavi gerektiren önemli bir halk sağlığı problemidir. Bu çalışma enfeksiyon kontrolünde yardımcı olabilecek onikomikoza ait kliniko-mikolojik özellikleri tespit etmek amacıyla planlandı. Bu çalışmanın amacı, risk faktörlerini analiz etmek ve klinik özellikleri tespit edebilmek için, onikomikozun değişik etken ajanlarının prevelansını belirlemekti. Bu çalışma 1 Şubat 2011-31 Ocak 2012 tarihleri arasında 1 yıllık periyotta SKIMS Kaşmir Tıp Fakültesi dermatoloji bölümüne başvuran klinik olarak tırnak enfeksiyonu şüphesi olan 150 hastadan alınan örnekler üzerinde yapılan prospektif bir çalışmadır. Tırnaklar klinik olarak değerlendirildi ve tırnak örnekleri direkt mikroskopi ve kültür yapılarak ile incelendi. Örneklerde %66.6’sı direkt mikroskopi ve kültürde pozitif idi. Erkekler bayanlardan daha fazla enfekte idi. En sık enfekte yaş grubu 21-30 yaş arası idi. El tırnakları ayak tırnaklarından daha fazla enfekte idi ve %66 hastada görülen distolateral subungal onikomikoz en sık klinik tip idi. Etiyolojik ajanlar dermatofit (%52.68), NDM (%29.85) ve yeast (%7.46) idi. Dermatofitler arasında T. Rubrum en sık etiyolojik ajan idi

Kaynakça

  • Kaur R, Kashyap P, Bhalla P. Onychomycosis-epidemiology, diagnosis and management. Indian J Med Microbiol 2008; 26(2): 108-16.
  • Scher P; Onychomycosis a significant medical disorder. J Am Acad Dermatol 1996; 35: S2-5.
  • Midgley G, Moore MK: Nail infections. Dermatol Clin 1996; 14: 41-9.
  • Williams HC. The epidemiology of onychomycosis in Britain. Br J Dermatol 1993; 129:101-9.
  • Odom RB. Common superficial fungal infections in im- munosuppressed patients. J Am Acad Dermatol 1994; 31: 556-9
  • Shenoy MM, Teerthnath S, Karnaker VK, Girisha BS, Krishna Prasad MS, Pinto J. Comparison of potassium hy- droxide mount and mycological culture with histopatho- logic examination using periodic acid-shiff staining of nail clippings in the diagnosis of onychomycosis. Indian J Dermatolol Veneorol Leprol 2008; 74:226-9.
  • Kaur R, Kashyap B, Bhalla P. A five year survey of onycho- mycosisin New Delhi, India: epidemiological and labora- tory aspects. Indian J Dermatolol 2007; 52: 39- 42.
  • Winberg JM, Koestenblatt EK, Turtone WD, Tishler HR. Najarian L. Comparison of diagnostic methods in the evaluation of onychomycosis. J Am Acad Dermatol 2003; 49(2) 193-7.
  • Alvarez MI, Gonzalez LA, Castro LA. Onychomycosis in Cali, Colombia. Mycopathologia 2004; 158: 181-6.
  • Garg A, Venkatesh V, Singh M, Pathak KP. Onychomycosis in Central India: a clinico etiological correlation. Int J Dermatol 2004; 43(7): 498-502.
  • Adhikari L, Gupta AD, Pal R, Singh T. Clinico-etiologic co-relates of onychomycosis in Sikkim. Indian J Pathol Microbiol; 52: 194-7.
  • Grover S. Clinico-mycological evaluation of onychomyco- sis at Banglore and Jorhat. Indian J Dermatolol Veneorol Leprol 2003; 69: 284-6.
  • Aghamirian MR, Ghiasian SA. Onychomycosis in Iran: epi- demiology, causative agents and clinical features. Jpn J Med Mycol 2010; 51: 23-9.
  • El Sayed F, Ammoury A,Haybe RF, Daybi R: Onychomycosis in Lebanon: a mycological survey of 772 patients. Mycoses 2006; 49:216-9.
  • Gupta AK, Jain HC, Lynde CW, Macdonald P, Cooper EA, Summerbell RC. Prevalence and epidemiology of onycho- mysis in patients visiting physicians offices: A multicentre Canadian survey of 15000 patients. J Am Acad Dermatol 2000; 43: 244-8.
  • Koursidou T, Devliotou Panagiotidou D, Karakatsanis G, Minas A, Mourellou O, Samara K. Onychomycosis in Northern Greece during 1994-98. Mycoses 2002; 45: 29- 37.
  • Veer P, Patwardhan NS, Damle AS. Study of 56.Onychomycosis: prevailing fungi and pattern of infec- tion. Indian J Med Microbiol 2007; 25: 53-6
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Makaleler
Yazarlar

Rubina Lone Bu kişi benim

Hakim İrfan Showkat Bu kişi benim

Deeba Bashir Bu kişi benim

Syed Khursheed Bu kişi benim

Arif Hussain Sarmast Bu kişi benim

Yayımlanma Tarihi 1 Eylül 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 10 Sayı: 3

Kaynak Göster

APA Lone, R., Showkat, H. İ., Bashir, D., Khursheed, S., vd. (2013). Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India. European Journal of General Medicine, 10(3), 150-153.
AMA Lone R, Showkat Hİ, Bashir D, Khursheed S, Sarmast AH. Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India. European Journal of General Medicine. Eylül 2013;10(3):150-153.
Chicago Lone, Rubina, Hakim İrfan Showkat, Deeba Bashir, Syed Khursheed, ve Arif Hussain Sarmast. “Clinico-Mycological Pattern of Onychomycosis: A Single Center One Year Study in Kashmir-North India”. European Journal of General Medicine 10, sy. 3 (Eylül 2013): 150-53.
EndNote Lone R, Showkat Hİ, Bashir D, Khursheed S, Sarmast AH (01 Eylül 2013) Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India. European Journal of General Medicine 10 3 150–153.
IEEE R. Lone, H. İ. Showkat, D. Bashir, S. Khursheed, ve A. H. Sarmast, “Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India”, European Journal of General Medicine, c. 10, sy. 3, ss. 150–153, 2013.
ISNAD Lone, Rubina vd. “Clinico-Mycological Pattern of Onychomycosis: A Single Center One Year Study in Kashmir-North India”. European Journal of General Medicine 10/3 (Eylül 2013), 150-153.
JAMA Lone R, Showkat Hİ, Bashir D, Khursheed S, Sarmast AH. Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India. European Journal of General Medicine. 2013;10:150–153.
MLA Lone, Rubina vd. “Clinico-Mycological Pattern of Onychomycosis: A Single Center One Year Study in Kashmir-North India”. European Journal of General Medicine, c. 10, sy. 3, 2013, ss. 150-3.
Vancouver Lone R, Showkat Hİ, Bashir D, Khursheed S, Sarmast AH. Clinico-Mycological pattern of Onychomycosis: A single center one year study in Kashmir-North India. European Journal of General Medicine. 2013;10(3):150-3.