CEP accounts for up to 2% of all cases of interstitial lung diseases and seem more frequently in females. Symptoms are generally nonspecific. Wheezing, haemoptysis and respiratory failure are rarely seen. Extra-thoracic system involvement if present, excludes a diagnosis of CEP. Diagnosis is based on; respiratory symptoms of more than 2 weeks duration, alveolar (>40% on Broncho-alveolar lavage) and/or blood eosinophilia (0.1 X109/L), pulmonary infiltrates with usually a peripheral predominance on chest imaging and exclusion of other causes of eosinophilia. The chest X-ray as in the index case, described as photographic negative of pulmonary oedema is characteristic of CEP and is seen in up to one fourth of patients.
Jederlinic PJ, Sicilian L, Gaensler EA. Chronic Eosinophilic pneumonia. A report of 19 cases and a review of the lit- erature. Medicine (Baltimore)1988; 67(3):154-62.
Allen JN, Davis WB. Eosinophilic lung diseases. Am J Respir Crit Care Med 1994; 150:1423-38.
Cordier JF. Eosinophilic pneumonias. In: Schwarz MI, King TE, eds. Interstitial Lung Disease. Hamilton, Ontario: BC Decker; 1998:559-95.
Raghu GA. Respiratory Diseases: interstitial lung disease. In:Goldman LE, Ausiello DA, eds.Cecil Text book of medi- cine 2008: Elsevier Inc;640-652
Yeon Joo eong YJ, Kim K, Seo J, et al. Eosinophilic Lung Diseases: A Clinical, Radiologic, and Pathologic Overview. RadioGraphics 2007; 27: 617-37.
Peros-Golubicic T, Smojver-Jezek S. Hypereosinophilic syndrome: diagnosis and treatment. Curr Opin Pulm Med 2007; 13(5):422-7.
Knudsen L, Gugger M, Dumont P, Nicod L, von Garnier C. A rare cause of acute respiratory failure and elevated eosinophils in broncho-alveolar lavage fluid. Respiration 2009; 77(2):224-8.
Jederlinic PJ, Sicilian L, Gaensler EA. Chronic Eosinophilic pneumonia. A report of 19 cases and a review of the lit- erature. Medicine (Baltimore)1988; 67(3):154-62.
Allen JN, Davis WB. Eosinophilic lung diseases. Am J Respir Crit Care Med 1994; 150:1423-38.
Cordier JF. Eosinophilic pneumonias. In: Schwarz MI, King TE, eds. Interstitial Lung Disease. Hamilton, Ontario: BC Decker; 1998:559-95.
Raghu GA. Respiratory Diseases: interstitial lung disease. In:Goldman LE, Ausiello DA, eds.Cecil Text book of medi- cine 2008: Elsevier Inc;640-652
Yeon Joo eong YJ, Kim K, Seo J, et al. Eosinophilic Lung Diseases: A Clinical, Radiologic, and Pathologic Overview. RadioGraphics 2007; 27: 617-37.
Peros-Golubicic T, Smojver-Jezek S. Hypereosinophilic syndrome: diagnosis and treatment. Curr Opin Pulm Med 2007; 13(5):422-7.
Knudsen L, Gugger M, Dumont P, Nicod L, von Garnier C. A rare cause of acute respiratory failure and elevated eosinophils in broncho-alveolar lavage fluid. Respiration 2009; 77(2):224-8.