IMPORTANCE OF OPEN LUNG BIOPSY IN PATIENTS SUSPECTED INTERSTITIAL LUNG DISEASE

Yıl 2007, Cilt: 4 Sayı: 1, - , 01.03.2007

INTERSTITIAL LUNG Dısease Hıdır Esme Murat Sezer Okan Solak Önder Şahin

Öz

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Anahtar Kelimeler

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IMPORTANCE OF OPEN LUNG BIOPSY IN PATIENTS SUSPECTED INTERSTITIAL LUNG DISEASE

Öz

Aim: The purpose of this study was to review the role of surgical lung biopsy techniques in patients with suspected interstitial lung disease to determine the outcomes in terms of diagnosis and management. Methods: Clinical courses and histolopathological reports of twenty four patients with suspected diagnosis of interstitial lung disease on clinical and radiological grounds were reviewed retrospectively. Twenty of the patients had undergone mini thoracotomy and four had undergone video-assisted thoracoscopic lung biopsy. Pathologic diagnosis had been established in all patients. Results: The most frequent diagnosis was sarcoidosis in six patients. As a result of histopathological examination the definite diagnosis and management of 9 (37.5%) patients had changed. Mean post-operative length of hospital stay and chest tube drainage duration was 3.6 days and 2.1 days, respectively. The overall morbidity rate was 12.5% and there was no mortality. Conclusion: Open lung biopsy can safely be performed in patients with suspected interstitial lung disease. The morbidity and mortality is low, length of hospital stay and chest tube drainage durations are relatively short. It alters the diagnosis and management in a significant number of patients

Anahtar Kelimeler

Open lung biopsy, interstitial lung disease, morbidity

Kaynakça

• Fulmer JD. An introduction to the interstitial lung disease. Clin Chest Med 1982;3:457–73
• Doi A, Iyenger S, Ferguson J, Ritchie AJ. VATS lung biopsy in suspected, diffuse interstitial lung disease provides diagnosis, and alters management strategies. Heart Lung Circ 2005;14:90-2
• Qureshi RA, Ahmed TA, Grayson AD, Soorae AS, Drakeley MJ, Page RD. Does lung biopsy help patients with interstitial lung disease? Eur J Cardiothorac Surg 2002;21:621-6
• Akgün M, Mirici A, Alper F. Idiyopatik interstisyel pnömoniler. Toraks Dergisi 2005; 6:251-63
• Rossiter SJ, Miller C, Churg AM, Carrington CB, Mark JB. Open lung biopsy patient: is it really beneficial? J Thorac Cardiovasc Surg 1979;77:338-45
• Colby TV, Swensen SJ. Anatomic distribution and histopathologic patterns in diffuse lung disease correlation with HRCT. J Thorac Imaging 1996;11:1-26
• Gal AA. Use and abuse of lung biopsy. Adv Anat Pathol 2005;12:195-202
• Travis WD, King TE Jr, Bateman ED, et al. American Thoracic Society/European Respiratory multidisciplinary consensus classification of the idiopathic interstitial pneumonias. Am J Respir Crit Care Med 2002;165: 277-304 international
• Flaherty KR, Travis WD, Colby TV, et al. Histopathologic variability in usual and nonspecific interstitial pneumonias. Am J Respir Crit Care Med 2001;164:1722-7
• Dacic S, Yousem SA. Idiopathic pulmonary classification of idiopathic chronic interstitial pneumonias. Am J Respir Cell Mol Biol 2003;29:5-9 histologic
• Raghu G. Interstitial lung disease: a diagnostic approach. Are CT scan and lung biopsy indicated in every patient? Am J Respir Crit Care Med 1995;151: 909-14