Conservative surgery and fertility outcomes of borderline ovarian tumours: Case series and review of literature

Yıl 2011, Cilt: 16 Sayı: 3, 225 - 227, 22.01.2013

Cihangir Mutlu Ercan Kazim Emre Karasahin İbrahim Alanbay Ali Kolusari Hakan Çoksuer Mufit Cemal Yenen

Öz

Abstract. Borderline ovarian tumours are usually seen in younger aged women and the issue of conservative surgery is increasingly important in today’s fertility-preserving concept. We present three borderline ovarian tumour cases who underwent conservative surgery in our instutition between 2006-2008 and their long-term follow-ups for their reproductive capacity after treatment. No recurrence after conservative treatment in our cases had been noted. Fertility-preserving surgery may be the treatment of choice with careful follow-up in women with Stage I borderline ovarian tumours, who desire further childbearing. Assisted Reproductive Techniques should be taken into consideration after the initial treatment and second-look surgery may be performed in the course of a caesarean section.

Key words: Tumors of low malignant potential, borderline ovarian tumors, conservative surgery

Anahtar Kelimeler

Tumors of low malignant potential, borderline ovarian tumors, conservative surgery

Kaynakça

• 1. Taylor HC. Malignant and semi-malignant tumours of the ovary. Surg Gynecol Obstet 1929; 48: 204-230.
• 2. FIGO. International Federation of Gynecology and Obstetrics Classification and staging of malignant tumours in the female pelvis. Acta Obstet Gynecol Scand 1971; 50: 1-7.
• 3. Trimbos JB, Parmar M, Vergote I, et al. International collaborative ovarian neoplasm trial 1 and adjuvant chemotherapy in ovarian neoplasm trial: two parallel randomized phase III trials of adjuvant chemotherapy in patients with earlystage ovarian carcinoma. J Natl Cancer Inst 2003; 95: 105-112.
• 4. Tropé C, Kaern J. Management of borderline tumors of the ovary: state of the art. Semin Oncol 1998; 25: 372-380.
• 5. Gotlieb WH, Flikker S, Davidson B, et al. Borderline tumors of the ovary: fertility treatment, conservative management, and pregnancy outcome. Cancer 1998; 82: 141-146.
• 6. Morris RT, Gershenson DM, Silva EG, et al. Outcome and reproductive function after conservative surgery for borderline ovarian tumors. Obstet Gynecol 2000; 95: 541-547.
• 7. Donnez J, Munschke A, Berliere M, et al. Safety of conservative management and fertility outcome in women with borderline tumors of the ovary. Fertil Steril 2003; 79: 1216– 1221.
• 8. Morice P, Camatte S, El Hassan J, et al. Clinical outcomes and fertility results after conservative treatment for ovarian borderline tumor. Fertil Steril 2001; 75: 92-96.
• 9. Lim-Tan SK, Cajigas HE, Scully RE. Ovarian cystectomy for serous borderline tumors: a follow-up study of 35 cases. Obstet Gynecol 1988; 72: 775-781.
• 10. Schilder JM, Thompson AM, DePriest PD, et al. Outcome of reproductive age women with stage IA or IC invasive epithelial ovarian cancer treated with fertility-sparing therapy. Gynecol Oncol 2002; 87: 1-7.
• 11. Pecorelli S, Odicino F, Maisonneuve P, et al. Carcinoma of the ovary. Annual report on the results of treatment of gynaecological cancer. J Epidemiol Biostat 1998; 3: 75-102.