Objective: To determine lethal doses of fixed and/or
volatile oils extracted from leafs or fruits of Pimpinella
anisum, Foeniculum vulgare, Sesamum indicum,
Eugenia caryophyllata, Nigella sativa, Urtica pilulifera,
Apium graveolens, Cuminum cyminum, Coriandrum
sativum and Thymus fallax.
Method: Swiss albino mice were injected
intraperitoneally with different concentrations of the
extract and results were evaluated with the method of
probit analysis.
Results: Maximum volume of oil administered to mice
was kept below 0.5 ml. The oils of Sesamum indicum
and Urtica pilulifera was completely non-lethal even at
doses reaching 12.8 ml/kg and considered non-toxic.
Conclusion: Lethal doses were determined for all other
plants and LD1, LD10, LD50, LD90 and LD99 values were
given.
Key words: Volatile oil, fixed oil, lethal doses, plants
Birincil Dil | İngilizce |
---|---|
Bölüm | Articles |
Yazarlar | |
Yayımlanma Tarihi | 27 Şubat 2013 |
Yayımlandığı Sayı | Yıl 2004 Cilt: 9 Sayı: 1 |