The effect of intravesical stent length and Propiverine on ureteral stent related symptoms - Prospective controlled trial

Yıl 2023, , 30 - 37, 30.01.2023

Osman Can , Mustafa Erkoç , Eyyüp Danış , Muammer Bozkurt , Alper Ötünçtemur , Halil Lütfi Canat

https://doi.org/10.54233/endouroloji.1195139

Öz

Objective: Ureteral double J stents are widely utilized in urolithiasis. Disturbing stent-related symptoms may occur while the stent is in location. Various medical agents and stent-related solutions were examined for this problem. However, a definite drug has still not been found. We aimed to research the effect of propiverine on stent-related symptoms.
Material and Methods: Patients who underwent ureteroscopic stone surgery between June 2020 and May 2022 were included in the study. While the control group was untreated, the treatment group received 45 mg of propiverine daily after 1 week of the operation. Stent-related symptoms were assessed by ureteral stent symptom questionnaire (USSQ) at the end of 1st week and 3rd week of surgery. In addition, the intravesical stent parts of all patients were quantitatively measured with a ruler during stent removal at the end of 3 weeks.
Results: A total of 177 patients were assessed in the study. Eighty-seven patients were control and 90 patients of them were treatment group. According to USSQ, urinary symptoms scores, body pain scores, general health scores, work performance scores, sexual health scores, additional problem scores, and global quality of life (QoL) scores were found to decrease in the treatment group (p<0.001 All domains). Intravesical stent length was found positive correlation with the urinary symptom score (1st week) of all patients.
Conclusion: Stent-related symptoms are more likely in patients with longer intravesical stent length. Propiverine successfully relieves stent-related symptoms.

Anahtar Kelimeler

Propiverine, Stent related symptom, Double J stent, USSQ

Üreteral stent ilişkili semptomlara intravezikal stent uzunluğunun ve Propiverin’in etkisi- Prospektif kontrollü çalışma

Öz

Amaç: Üreteral double J stentler taş hastalıklarında sıklıkla kullanılmaktadır. Stent normal lokalizasyonunda iken stent ilişkili rahatsız edici sempomlara neden olabilmektedir. Bu problem için çeşitli medikal ajanlar ve stent ilişkili çözümler araştırılmıştır. Ancak hala kesin bir ilaç bulunamamıştır. Biz stent ilişkili semptomlar üzerinde propiverinin etkisini araştırmayı amaçladık.
Gereç ve Yöntemler: Çalışmaya haziran 2020 ile mayıs 2022 tarihleri arasında üreteroskopik taş cerrahisi yapılan hastalar dahil edildi. Kontrol grubu tedavi almaz iken tedavi grubu operasyonun 1. haftasından sonra günlük 45 mg propiverin aldı. 1. ve 3. haftanın sonunda stent ilişkili semptomlar üreteral stent semptom anketi (USSQ) ile değerlendirildi. Ek olarak tüm hastaların 3. Hafta sonunda stent alınması sırasında intravezikal stent kısımları cetvel ile ölçüldü.
Bulgular: Çalışmada toplamda 177 hasta değerlendirildi. Bunlardan 87si kontrol grubunu oluştururken 90 hasta tedavi grubunu oluşturdu. USSQ skorlarına göre, üriner semptom skorları, vücut ağrı skorları, genel sağlık skorları, iş performansı skorları, cinsel sağlık skorları, ek problemler skoru ve global hayat kalitesi skoru tedavi gruplarında azalmış bulundu (p<0,001 tüm alanlarda). Tüm hastalarda intravezikal stent uzunluğu 1. hafta sonundaki üriner semptom skoru ile pozitif korele olarak bulundu.
Sonuç: Stent ilişkili semptomlar intravezikal stent boyu daha uzun olanlarda daha fazladır. Propiverin stent ilişkili semptomları başarılı şekilde rahatlatmaktadır.

Anahtar Kelimeler

Stent ilişkili semptom, Propiverin, Double J stent, USSQ

Kaynakça

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