Transüretral mesane tümörü rezeksiyonu patoloji örneğinde detrusor kas dokusunun varlığını etkileyen faktörler

Yıl 2020, Cilt: 12 Sayı: 3, 204 - 209, 31.12.2020

Erhan Demirelli , Ercan Öğreden , Mefail Aksu , Mehmet Karadayı Ural Oğuz

Öz

Amaç: Mesane tümörü patolojik incelemesinde detrusor kas dokusunun (DKD) ortaya konulması doğru evreleme ve transüretral mesane tümörü rezeksiyonu (TUR-MT) sonrası tedavi planlanmasında oldukça önem arz eder. Bu çalışmada TUR-MT sonrası patoloji spesmeninde DKD örneklenmesine etki eden faktörleri belirlemeyi amaçladık.

Gereç ve Yöntemler: Kliniğimizde primer mesane tümörü nedeniyle TUR-MT yapılan ve ameliyat notunda tümörün lokalizasyonunun işaretlendiği mesane diyagramı kullanılan 59 hastanın dosyaları retrospektif olarak incelendi. Patoloji spesmeninde DKD izlenmeyen 26 hasta grup I, DKD izlenen 33 hasta grup II olarak isimlendirildi. Gruplar arasında yaş, cinsiyet, tümör sayısı, tümör boyutu ve tümör lokalizasyonu açısından fark olup olmadığı incelendi.

Bulgular: Çalışmamızda DKD izlenme oranı %56 olarak tespit edildi. Hastaların yaş ortalamaları grup I’ de 69.5±10.2 iken grup II’ de 68.7 ± 9.2 idi (p=0.755). İki grup arasında cinsiyet dağılımı açısından istatistiksel olarak anlamlı fark saptanmadı (p=0.646). Tümör lokalizasyonuna baktığımızda grup I de tümörlerin %11.5’i kubbede, %11.5’i karşı duvarda ve %77’ si yan duvarlarda; grup 2’ de ise %6.1’i kubbede, %27.2’ si karşı duvarda ve %66.7’ si de yan duvarlarda izlendi. Grup I ve grup II arasında tümör lokalizasyonu açısından anlamlı fark saptanmadı (p>0.05). Ortalama tümör sayısının ve tümör boyutlarının her iki grupta da istatistiksel olarak benzer olduğu saptandı (p>0,05).

Sonuç: Hastaların patolojik örneklerinde DKD görülmesine yaş, cinsiyet, tümör boyutu, tümör sayısı, tümörün mesane duvarındaki lokalizasyonu gibi değişkenlerin etkisinin olmadığı saptandı.

Anahtar Kelimeler

Mesane tümörü, TUR-MT, Tümör lokalizasyonu, Detrusor kas tabakası

Factors affecting presence of detrusor muscle tissue in pathology specimen of transurethral bladder tumor resection

Öz

Objective: Sampling of detrusor muscle tissue (DMT) in the pathological examination of the bladder tumor is very important in the planning of correct staging and treatment. In the present study, we aimed to determine the factors affecting the DMT sampling in the pathology specimen after TUR-BT.

Material and Mmethodsː The medical records of 59 patients who underwent TUR-BT were retrospectively analyzed. Twenty-six patients who had no DMT in the pathology specimen were classified as group I and 33 patients with DMT were classified as group II. Differences between groups in terms of age, gender, tumor number, tumor size, and tumor localization were examined.

Resultsː DMT was found in 56% of pathology specimens. There was no statistically significant difference in terms of gender distribution between the two groups (p=0.646). Tumor localizations were as follows; 11.5% is on the dome, 11.5% is on the opposite wall and 77% is on the side walls in group I; and In group 2, 6.1% were found on the dome, 27.2% on the opposite wall and 66.7% on the side walls. There was no statistically significant difference between group I and group II in terms of tumor localization (p>0.05). The mean number of tumors and mean tumor size was found to be statistically similar in both groups (p>0.05).

Conclusionsː It was concluded that variables such as age, gender, tumor size, number of tumors, and localization of the tumor did not affect the presence of DMT in the pathological specimen of the patients.

Anahtar Kelimeler

Bladder cancer, TUR-BT, Tumor localization, Detrusor muscle tissue

Kaynakça

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