Medical Treatment of Urinary System Stones

Yıl 2024, Cilt: 16 Sayı: 3, 108 - 115, 29.09.2024

Hasan Turgut , Mehmet Sarıer

https://doi.org/10.54233/endourolbull-1493466

Öz

In urinary tract stone disease, medical treatment is of great importance both to increase stone passage and to prevent recurrence.Adequate fluid intake, dietary habits, increased fiber intake, low vitamin C and protein intake can be recommended in all patients with urolithiasis regardless of stone type.Pharmacologic agents such as alpha blockers and calcium channel blockers have been used for a long time to increase spontaneous passage of urinary tract stones. Medical treatment of calcium stones includes thiazides, alkaline citrate, allopurinol and glycosaminoglycans. Urine alkalinization, restriction of protein and purine intake in the diet and allopurinol are used in the medical treatment of uric acid stones. Urine alkalinization, cystine binding drugs and restriction of methionine intake are effective in cystine stonesUrease inhibitors, antibiotics and urine acidification are commonly used methods in the medical treatment of infection stones

Anahtar Kelimeler

Kidney stone, diet therapy, ureteral stone, renal colic, medical expulsive therapy, metaphylaxis

Üriner Sistem Taşlarında Medikal Tedavi

Öz

Üriner sistem taş hastalığında hem taş pasajını artırmak hem de rekürrensin önlemesinde medikal tedavinin yeri oldukça büyük öneme sahiptir.Yeterli sıvı alımı,diyet alışkanlığı,lifli gıdaların artırılması,düşük c vitamini ve protein alımı taş tipine bakılmaksızın tüm ürolitiazisli hastalarda önerilebilir.Ürine sistem taşlarında taşın spontan pasajını artırmak için alfa bloker ve kalsiyum kanal blokerleri gibi farmakolojik ajanlar uzun süredir kullanılan medikal tedavilerdir. Kalsiyum taşlarının medikal tedavisini tiazidler, alkalen sitrat, allopurinol ve glikozaminoglikanlar oluşturur. Ürik asit taşlarının medikal tedavisinde ise idrar alkalinizasyonu, diyette protein ve pürin alımının kısıtlanması ve allopürinol kullanılır. Sistin taşlarında idrar alkalinizasyonu, sistin bağlayıcı ilaçlar ve metionin alımının kısıtlanması etkilidir. Enfeksiyon taşlarının medikal tedavisinde ise üreaz inhibitörleri, antibiyotikler ve idrar asidifikasyonu yaygın kullanılan yöntemlerdir.

Anahtar Kelimeler

Böbrek taşı, diyet tedavisi, üreter taşı, renal kolik, medikal ekspulsif terapi, metaflaksi

Kaynakça

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