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Ortopedide MikroRNA Çalışmalarının Araştırma Eğilimleri: Bibliyometrik Analiz Çalışması

Yıl 2024, Cilt: 5 Sayı: 3, 117 - 121, 30.11.2024

Öz

Giriş: MikroRNA (miRNA) tek bir nükleotid dizisinden oluşan bir moleküldür. Keşfi en son bilimsel buluşlardan biri olarak kabul edilmektedir. MikroRNA hem tanı hem de tedavi için büyük umut vaat etmektedir. MikroRNA, ortopedi de dahil olmak üzere birçok alanda kapsamlı olarak çalışılmış olmasına rağmen, son yıllarda ortopediye özgü bir bibliyometrik analiz yapılmamıştır. Ortopedik araştırmalarda yayınlanan mikroRNA çalışmalarının kapsamlı bilgi haritasını, gelişim ortamını ve gelecekteki yönelimlerini özetlemeyi amaçladık.
Yöntemler: Bu çalışmada bibliyometrik bir yaklaşım kullandık. Web of Science veri tabanı, 2003 ve 2022 yılları arasında ortopedik araştırmalarda yayınlanan mikroRNA çalışmalarını almak için kullanıldı. Analiz için Biblioshiny ve VOSviewer araçları kullanıldı.
Bulgular: Ortopedi alanında 1601 yazar tarafından miRNA ile ilgili toplam 292 araştırma makalesi yayınlandı. Yıllık büyüme oranı %23,12 idi. 2021 yılı en fazla makale (n=62) ve atıf (n=946) alan yıl oldu. Yayınlar, çoğunluğu Çin (n=182, %62,329) ve Amerika Birleşik Devletleri'nden (n=52, %17,808) olmak üzere 28 ülkeden geldi. Çin'in yayınları diğer ülkelere kıyasla artmaya devam etmiştir.
Sonuç: Yayın sayısı diğer araştırma alanlarına kıyasla düşük olsa da ortopedide mikroRNA üzerine yapılan küresel araştırmalar son on yılda daha fazla dikkat çekmiştir. Sonuçlarımız, araştırmacıların temel bilgi yapısını kavramaları ve bu alandaki mevcut araştırma noktalarını, potansiyel ortakları ve gelecekteki araştırma sınırlarını belirlemeleri için yararlı bilgiler sağlamaktadır.

Etik Beyan

Not applicable.

Destekleyen Kurum

Not applicable.

Teşekkür

Not applicable.

Kaynakça

  • 1. Lu TX, Rothenberg ME. MicroRNA. Journal of Allergy and Clinical Immunology. 2018;141:1202-7.
  • 2. Weber JA, Baxter DH, Zhang S, et al. The microRNA spectrum in 12 body fluids. Clin Chem. 2010;56:1733-41.
  • 3. Mohr A, Mott J. Overview of MicroRNA Biology. Semin Liver Dis. 2015;35:3-11.
  • 4. Rupaimoole R, Slack FJ. MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. Nat Rev Drug Discov. 2017;16:203-22.
  • 5. Simonson B, Das S. MicroRNA Therapeutics: the Next Magic Bullet? MRMC. 2015;15:467-74.
  • 6. Jones TL, Esa MS, Li KHC, et al. Osteoporosis, fracture, osteoarthritis & sarcopenia: A systematic review of circulating microRNA association. Bone. 2021;152:116068.
  • 7. Lu C, Buckley JM, Colnot C, Marcucio R, Miclau T. Basic research in orthopedic surgery: Current trends and future directions. Indian J Orthop. 2009;43:318-23.
  • 8. Nakasa T, Nagata Y, Yamasaki K, Ochi M. A mini-review: microRNA in arthritis. Physiological Genomics. 2011;43:566-70.
  • 9. Fariyike B, Singleton Q, Hunter M, et al. Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview. Mechanisms of Ageing and Development. 2019;178:9-15.
  • 10. Lv F, Qin J, Kong S, Pan L, Ding R. MicroRNA‐506 ameliorates breast cancer‐induced osteolytic bone metastasis via the NFATc‐1 signaling pathway. J Biochem & Molecular Tox. 2022;36:e23156.
  • 11. Ram Kumar R, Boro A, Fuchs B. Involvement and Clinical Aspects of MicroRNA in Osteosarcoma. IJMS. 2016;17:877.
  • 12. Wu H, Tong L, Wang Y, Yan H, Sun Z. Bibliometric Analysis of Global Research Trends on Ultrasound Microbubble: A Quickly Developing Field. Front Pharmacol. 2021;12:646626.
  • 13. Ekici A, Alkan S, Aydemir S, Gurbuz E, Unlu AH. Trends in Naegleria fowleri global research: A bibliometric analysis study. Acta Tropica. 2022;234:106603.
  • 14. Şahi̇N S. Research trends and top cited articles on the frozen elephant trunk procedure. Genel Tıp Dergisi. 2022;32:740-5.
  • 15. Alkan-Ceviker S, Onturk H, Alıravcı ID, Sıddıkoğlu D. Trends of COVID 19 Vaccines: International Collaboration and Visualized Analysis. Infect Dis Clin Microbiol. 2021;3:129-36.
  • 16. Kurt M. Protez Enfeksiyonları Konulu Bilimsel Çıktıların Analizi. Black Sea Journal of Health Science. 2023;6:34-9.
  • 17. Di̇ndar Demi̇ray EK, Alkan S, Yüksel C. Investigation of Global Trends in Publications on Syphilis with Bibliometrics. Black Sea Journal of Health Science. 2022;5:379-86.
  • 18. Chen L, Heikkinen L, Wang C, Yang Y, Sun H, Wong G. Trends in the development of miRNA bioinformatics tools. Briefings in Bioinformatics. 2019;20:1836-52.
  • 19. Yan XY, Yao JP, Li YQ, et al. Global trends in research on miRNA–microbiome interaction from 2011 to 2021: A bibliometric analysis. Front Pharmacol. 2022;13:974741.
  • 20. Lim M, Carollo A, Neoh MJY, Esposito G. Mapping miRNA Research in Schizophrenia: A Scientometric Review. IJMS. 2022;24:436.
  • 21. van Eck NJ, Waltman L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics. 2010;84:523-38.
  • 22. Aria M, Cuccurullo C. bibliometrix : An R-tool for comprehensive science mapping analysis. Journal of Informetrics. 2017;11:959-75.
  • 23. Hirsch JE. An index to quantify an individual’s scientific research output. Proc Natl Acad Sci USA. 2005;102:16569-72.
  • 24. O’Neill SC, Butler JS, McGoldrick N, O’Leary R, Synnott K. The 100 most cited papers in spinal deformity surgery: a bibliometric analysis. Orthop Rev (Pavia). 2014;6:5584.
  • 25. Alkan S, Gökçe ON, Şahi̇noğlu MS. A Quantitative Study of The Most Influential Articles on Cytomegalovirus in Solid Organ Transplantation. Journal of Biotechnology and Strategic Health Research. 2022;6:122-30.

Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study

Yıl 2024, Cilt: 5 Sayı: 3, 117 - 121, 30.11.2024

Öz

Introduction: MicroRNA (miRNA) is a molecule consisting of a single nucleotide sequence. Its discovery is considered one of the most recent scientific breakthroughs. MicroRNA holds great promise for both diagnosis and treatment. Although microRNA has been extensively studied in many fields, including orthopaedics, a bibliometric analysis specific to orthopaedics has not been performed in recent years. We aimed to summarise the comprehensive information map, development landscape, and future directions of microRNA studies published in orthopaedic research.

Methods: In this study, we used a bibliometric approach. The Web of Science database was used to retrieve microRNA studies published in orthopedic research between 2003 and 2022. Biblioshiny and VOSviewer tools were used for analysis.

Results: A total of 292 research articles on miRNA were published in the field of orthopaedics by 1601 authors. The annual growth rate was 23.12%. 2021 was the year with the highest number of articles (n=62) and citations (n=946). The publications came from 28 countries, with the majority coming from China (n=182, 62.329%) and the United States (n=52, 17.808%). China's publications continued to increase compared to other countries.

Conclusions: Although the number of publications is low compared to other research areas, global research on microRNA in orthopaedics has gained more attention in the last decade. Our results provide useful information for researchers to grasp the basic knowledge structure and identify current research hotspots, potential partners, and future research frontiers in this field.

Kaynakça

  • 1. Lu TX, Rothenberg ME. MicroRNA. Journal of Allergy and Clinical Immunology. 2018;141:1202-7.
  • 2. Weber JA, Baxter DH, Zhang S, et al. The microRNA spectrum in 12 body fluids. Clin Chem. 2010;56:1733-41.
  • 3. Mohr A, Mott J. Overview of MicroRNA Biology. Semin Liver Dis. 2015;35:3-11.
  • 4. Rupaimoole R, Slack FJ. MicroRNA therapeutics: towards a new era for the management of cancer and other diseases. Nat Rev Drug Discov. 2017;16:203-22.
  • 5. Simonson B, Das S. MicroRNA Therapeutics: the Next Magic Bullet? MRMC. 2015;15:467-74.
  • 6. Jones TL, Esa MS, Li KHC, et al. Osteoporosis, fracture, osteoarthritis & sarcopenia: A systematic review of circulating microRNA association. Bone. 2021;152:116068.
  • 7. Lu C, Buckley JM, Colnot C, Marcucio R, Miclau T. Basic research in orthopedic surgery: Current trends and future directions. Indian J Orthop. 2009;43:318-23.
  • 8. Nakasa T, Nagata Y, Yamasaki K, Ochi M. A mini-review: microRNA in arthritis. Physiological Genomics. 2011;43:566-70.
  • 9. Fariyike B, Singleton Q, Hunter M, et al. Role of MicroRNA-141 in the Aging Musculoskeletal System: A Current Overview. Mechanisms of Ageing and Development. 2019;178:9-15.
  • 10. Lv F, Qin J, Kong S, Pan L, Ding R. MicroRNA‐506 ameliorates breast cancer‐induced osteolytic bone metastasis via the NFATc‐1 signaling pathway. J Biochem & Molecular Tox. 2022;36:e23156.
  • 11. Ram Kumar R, Boro A, Fuchs B. Involvement and Clinical Aspects of MicroRNA in Osteosarcoma. IJMS. 2016;17:877.
  • 12. Wu H, Tong L, Wang Y, Yan H, Sun Z. Bibliometric Analysis of Global Research Trends on Ultrasound Microbubble: A Quickly Developing Field. Front Pharmacol. 2021;12:646626.
  • 13. Ekici A, Alkan S, Aydemir S, Gurbuz E, Unlu AH. Trends in Naegleria fowleri global research: A bibliometric analysis study. Acta Tropica. 2022;234:106603.
  • 14. Şahi̇N S. Research trends and top cited articles on the frozen elephant trunk procedure. Genel Tıp Dergisi. 2022;32:740-5.
  • 15. Alkan-Ceviker S, Onturk H, Alıravcı ID, Sıddıkoğlu D. Trends of COVID 19 Vaccines: International Collaboration and Visualized Analysis. Infect Dis Clin Microbiol. 2021;3:129-36.
  • 16. Kurt M. Protez Enfeksiyonları Konulu Bilimsel Çıktıların Analizi. Black Sea Journal of Health Science. 2023;6:34-9.
  • 17. Di̇ndar Demi̇ray EK, Alkan S, Yüksel C. Investigation of Global Trends in Publications on Syphilis with Bibliometrics. Black Sea Journal of Health Science. 2022;5:379-86.
  • 18. Chen L, Heikkinen L, Wang C, Yang Y, Sun H, Wong G. Trends in the development of miRNA bioinformatics tools. Briefings in Bioinformatics. 2019;20:1836-52.
  • 19. Yan XY, Yao JP, Li YQ, et al. Global trends in research on miRNA–microbiome interaction from 2011 to 2021: A bibliometric analysis. Front Pharmacol. 2022;13:974741.
  • 20. Lim M, Carollo A, Neoh MJY, Esposito G. Mapping miRNA Research in Schizophrenia: A Scientometric Review. IJMS. 2022;24:436.
  • 21. van Eck NJ, Waltman L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics. 2010;84:523-38.
  • 22. Aria M, Cuccurullo C. bibliometrix : An R-tool for comprehensive science mapping analysis. Journal of Informetrics. 2017;11:959-75.
  • 23. Hirsch JE. An index to quantify an individual’s scientific research output. Proc Natl Acad Sci USA. 2005;102:16569-72.
  • 24. O’Neill SC, Butler JS, McGoldrick N, O’Leary R, Synnott K. The 100 most cited papers in spinal deformity surgery: a bibliometric analysis. Orthop Rev (Pavia). 2014;6:5584.
  • 25. Alkan S, Gökçe ON, Şahi̇noğlu MS. A Quantitative Study of The Most Influential Articles on Cytomegalovirus in Solid Organ Transplantation. Journal of Biotechnology and Strategic Health Research. 2022;6:122-30.
Toplam 25 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Ortopedi
Bölüm Araştırma Makaleleri
Yazarlar

Turan Dülgeroğlu 0000-0002-9661-5418

Mehmet Kurt 0000-0003-3831-100X

Mehmet Yiğit Gökmen 0000-0003-1243-2057

Mesut Uluöz 0000-0003-0319-3832

Yayımlanma Tarihi 30 Kasım 2024
Gönderilme Tarihi 16 Ağustos 2024
Kabul Tarihi 12 Eylül 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 5 Sayı: 3

Kaynak Göster

APA Dülgeroğlu, T., Kurt, M., Gökmen, M. Y., Uluöz, M. (2024). Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study. Eskisehir Medical Journal, 5(3), 117-121.
AMA Dülgeroğlu T, Kurt M, Gökmen MY, Uluöz M. Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study. Eskisehir Med J. Kasım 2024;5(3):117-121.
Chicago Dülgeroğlu, Turan, Mehmet Kurt, Mehmet Yiğit Gökmen, ve Mesut Uluöz. “Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study”. Eskisehir Medical Journal 5, sy. 3 (Kasım 2024): 117-21.
EndNote Dülgeroğlu T, Kurt M, Gökmen MY, Uluöz M (01 Kasım 2024) Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study. Eskisehir Medical Journal 5 3 117–121.
IEEE T. Dülgeroğlu, M. Kurt, M. Y. Gökmen, ve M. Uluöz, “Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study”, Eskisehir Med J, c. 5, sy. 3, ss. 117–121, 2024.
ISNAD Dülgeroğlu, Turan vd. “Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study”. Eskisehir Medical Journal 5/3 (Kasım 2024), 117-121.
JAMA Dülgeroğlu T, Kurt M, Gökmen MY, Uluöz M. Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study. Eskisehir Med J. 2024;5:117–121.
MLA Dülgeroğlu, Turan vd. “Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study”. Eskisehir Medical Journal, c. 5, sy. 3, 2024, ss. 117-21.
Vancouver Dülgeroğlu T, Kurt M, Gökmen MY, Uluöz M. Research Trends of MicroRNA Studies in Orthopedics: A Bibliometric Analysis Study. Eskisehir Med J. 2024;5(3):117-21.