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Bor’un Kullanım Alanları ve Bor Toksisitesi

Yıl 2022, Cilt: 2 Sayı: 2, 115 - 121, 30.09.2022

Selcen Çakır

Öz

Bor (B) doğada birçok mineral formunda bulunan ve sanayide birçok alanda kullanılan değerli ve çok önemli bir elementtir. B, özellikle son çalışmalarla sağlık alanında da tercih edilmektedir. Osteoporoz, alerjik hastalılar, artrit, beyin kanserleri gibi birçok hastalığın tedavisi için kullanılmaktadır. B’a besin takviyesi olarak da ulaşmak mümkündür. Sağlık açısından birçok faydası bulunan B elementinin toksik olduğu durumlar da vardır. Bu çalışma ile B’un fiziksel ve kimyasal özelliklerinden, doğada bulunuş şekillerinden, kullanım alanlarından, sağlık için öneminden ve toksisitesinden bahsederek bir derleme yapıldı.

Anahtar Kelimeler

bor sağlık toksisite borik asit

Destekleyen Kurum

Bu çalışma desteklenmemiştir

Kaynakça

  • [1]. R. Kuru, S. Yılmaz, P. N. Taslı, A.Yarat, F. Sahın, Boron Content of Some Foods Consumed in Istanbul, Turkey. Biological trace element research, 1-8, 2018.
  • [2]. WHO. Boron. International Programme on Chemical Safety. Environmental Health Criteria 204, Ohio, USA, 1-201, 1998.
  • [3]. Toxicological review of boron and compounds. Environmental Protection Agency, 1-131, 2004.
  • [4]. FH. Nielsen, Nutritional requirements for boron, silicon, vanadium, nickel, and arsenic: current knowledge and speculation. FASEB J, 5, 2661-2667, 1991.
  • [5]. S. Çakır, M. Eren, Bor’un Oksidatif Stes ve DNA Hasarı Üzerine Etkisi. Sağlık Bilimleri Dergisi, 25, 88-91, 2016.
  • [6]. WG. Woods, An introduction to boron: history, sources, uses, and chemistry. Environ Health Perspect, 102, 5-11, 1994.
  • [7]. Z. Uçkun, Esansiyel bir komponent: bor- borun günlük alımı ve fizyolojik etkileri. Türk Bilimsel Derlemeler Dergisi, 6, 119-123, 2013.
  • [8]. A. Demirtaş, Bor’un insan beslenmesi ve sağlığı açısından önemi. Atatürk Üniversitesi Ziraat Fakültesi Dergisi, 41, 75-80, 2010.
  • [9]. B. Bilgiç, M. Dayık, Borun özellikleri ve tekstil endüstrisinde kullanımıyla sağladığı avantajlar. Electronic Journal of Textile Technologies, 7, 27-37, 2013.
  • [10]. TA. Devirian, ST. Volpe, The physiological effects of dietary boron. Critical Reviews in Food Science and Nutrition, 43, 219-231, 2003.
  • [11]. WHO, Trace Elements in Human Nutrition and Health: Boron. Geneva, 175-182, 1996.
  • [12]. FH. Nielsen, Boron-an overlooked elements of potential nutritional importance. Nutr Today, 4-7, 1988.
  • [13]. CD. Hunt, The biochemicals effects of physiologic amounts of diatery boron in animal nutritions models. Environ Health Perspects, 102, 35-43, 1994.
  • [14]. N. Hadrup, M. Frederiksen, and AK. Sharma, Toxicity of boric acid, borax and other boron containing compounds: A review. Regulatory toxicology and pharmacology, 104873, 121.
  • [15]. FH. Nielsen, Boron in human and animal nutrition. Plant and Soil, 199-208, 1997.
  • [16]. FH. Nielsen, Is boron nutritionally relevant? Nutrition Reviews, 66, 183-91, 2008.
  • [17]. D. Uygan, O. Çetin, Borun Tarımsal ve Çevresel Etkileri: Seydi suyu Toplama Havzası Koy Hizmetleri Araştırma Enstitüsü, Su Yönetimi Bolumu, Eskişehir, 2004.
  • [18]. J. Ducey, and DB Williams, Transcutaneous absorption of boric acid. The Journal of Pediatrics, 43, 6, 644-651, 1953.
  • [19]. HM. Bolt, N. Basaran, Y. Duydu, Effects of boron compounds on human reproduction. Arch. Toxicol. 94, 717–724. https://doi.org/10.1007/s00204-020- 02700-x, 2020.
  • [20]. C. Sevim, and M. Kara. Boron and Boron-Containing Compounds Toxicity. The Toxicity of Environmental Pollutants. Intech Open, doi: 10.5772/intechopen.103179, 2022.
  • [21]. K. Messner, B. Vuong, and GK. Tranmer. The Boron Advantage: The Evolution and Diversification of Boron’s Applications in Medicinal Chemistry. Pharmaceuticals,15.3, 264, 2022.
  • [22]. CD. Hunt, Regulation of enzymatic activity: one possible role of dietary boron in higher animals and humans. Biol Trace Elem Res, 205-225, 1998.
  • [23]. CD. Hunt, FH. Nielsen, Interaction Between Boron and Chholecalciferol in the Chicks. Australian Academy of Science. 97, 600. 1981. [24]. FH. Nielsen, Dietary Fat Composition Modifies the Effect of Boron on Bone Characteristics and Plasma Lipids in Rats. Biofactors, 161-171, 2004.
  • [25]. R. Kuru, A. Yarat, Bor ve Sağlığımıza Olan Etkilerine Güncel Bir Bakış. Clin Exp Health Sci, 104-114, 2017.
  • [26]. RJ. Weir, RS. Fisher, Toxicologic studies on borax and boric acid. Toxicol Appl Pharmacol, 351-364. 1972.
  • [27]. JE. Sander, L. Dufour, RD. Wyatt, PB. Bush, RK. Page, Acute toxicity of boric acid and boron tissue residues after chronic exposure in broiler chickens. Avian Dis, 35, 745-749, 1991.
  • [28]. W. Ku, R. Chapin, Mechanism of the testicular toxicity of boric acid in rats: invivo and invitro studies. Environ Health Perspect, 99-105, 1994.
  • [29]. CJ. Price, PL. Strong, FJ. Murray, MM. Goldberg, Blood boron concentrations in pregnant rats fed boric acid throughout gestation. Reported Toxicol, 11, 6, 833-42, 1997.
  • [30]. E. Reagan, Acute dermal toxicity study of sodium tetraboratedecahydrate in New Zealand white rabbits: lab project number: 8403A. Unpublished study prepared by Food & Drug Research Labs, Inc. 9 p. MRID 43553200, 1985.
  • [31]. E. Reagan, Primary eye irritation study of sodium tetraborate decahydrate in New Zealand white rabbits: lab project number: 8403B. Unpublished study prepared by Food & Drug Research Labs, Inc. 21 p. MRID 43553202, 1985.
  • [32]. HM. Dani, HS. Saini, IS. Allag, B. Singh, K. Sareen, Effect of boron toxicity on protein andnucleic acid contents of rat tissues. Res Bull Panjab Univ Sci, 22, 1– 2, 229-235, 1971.

Uses of Boron and Boron Toxicity

Yıl 2022, Cilt: 2 Sayı: 2, 115 - 121, 30.09.2022

Selcen Çakır

Öz

Boron (B) is a valuable and very important element found in many mineral forms in nature and used in many fields in industry. B is also preferred in the field of health, especially with recent studies. It is used for the treatment of many diseases such as osteoporosis, allergic diseases, arthritis, and brain cancers. It is also possible to reach B as a nutritional supplement. There are cases where element B, which has many health benefits, is toxic. In this study, a review was made by mentioning the physical and chemical properties of B, the way it is found in nature, its usage areas, its importance for health, and its toxicity.

Anahtar Kelimeler

Boron Health Toxicity Boric acid

Kaynakça

  • [1]. R. Kuru, S. Yılmaz, P. N. Taslı, A.Yarat, F. Sahın, Boron Content of Some Foods Consumed in Istanbul, Turkey. Biological trace element research, 1-8, 2018.
  • [2]. WHO. Boron. International Programme on Chemical Safety. Environmental Health Criteria 204, Ohio, USA, 1-201, 1998.
  • [3]. Toxicological review of boron and compounds. Environmental Protection Agency, 1-131, 2004.
  • [4]. FH. Nielsen, Nutritional requirements for boron, silicon, vanadium, nickel, and arsenic: current knowledge and speculation. FASEB J, 5, 2661-2667, 1991.
  • [5]. S. Çakır, M. Eren, Bor’un Oksidatif Stes ve DNA Hasarı Üzerine Etkisi. Sağlık Bilimleri Dergisi, 25, 88-91, 2016.
  • [6]. WG. Woods, An introduction to boron: history, sources, uses, and chemistry. Environ Health Perspect, 102, 5-11, 1994.
  • [7]. Z. Uçkun, Esansiyel bir komponent: bor- borun günlük alımı ve fizyolojik etkileri. Türk Bilimsel Derlemeler Dergisi, 6, 119-123, 2013.
  • [8]. A. Demirtaş, Bor’un insan beslenmesi ve sağlığı açısından önemi. Atatürk Üniversitesi Ziraat Fakültesi Dergisi, 41, 75-80, 2010.
  • [9]. B. Bilgiç, M. Dayık, Borun özellikleri ve tekstil endüstrisinde kullanımıyla sağladığı avantajlar. Electronic Journal of Textile Technologies, 7, 27-37, 2013.
  • [10]. TA. Devirian, ST. Volpe, The physiological effects of dietary boron. Critical Reviews in Food Science and Nutrition, 43, 219-231, 2003.
  • [11]. WHO, Trace Elements in Human Nutrition and Health: Boron. Geneva, 175-182, 1996.
  • [12]. FH. Nielsen, Boron-an overlooked elements of potential nutritional importance. Nutr Today, 4-7, 1988.
  • [13]. CD. Hunt, The biochemicals effects of physiologic amounts of diatery boron in animal nutritions models. Environ Health Perspects, 102, 35-43, 1994.
  • [14]. N. Hadrup, M. Frederiksen, and AK. Sharma, Toxicity of boric acid, borax and other boron containing compounds: A review. Regulatory toxicology and pharmacology, 104873, 121.
  • [15]. FH. Nielsen, Boron in human and animal nutrition. Plant and Soil, 199-208, 1997.
  • [16]. FH. Nielsen, Is boron nutritionally relevant? Nutrition Reviews, 66, 183-91, 2008.
  • [17]. D. Uygan, O. Çetin, Borun Tarımsal ve Çevresel Etkileri: Seydi suyu Toplama Havzası Koy Hizmetleri Araştırma Enstitüsü, Su Yönetimi Bolumu, Eskişehir, 2004.
  • [18]. J. Ducey, and DB Williams, Transcutaneous absorption of boric acid. The Journal of Pediatrics, 43, 6, 644-651, 1953.
  • [19]. HM. Bolt, N. Basaran, Y. Duydu, Effects of boron compounds on human reproduction. Arch. Toxicol. 94, 717–724. https://doi.org/10.1007/s00204-020- 02700-x, 2020.
  • [20]. C. Sevim, and M. Kara. Boron and Boron-Containing Compounds Toxicity. The Toxicity of Environmental Pollutants. Intech Open, doi: 10.5772/intechopen.103179, 2022.
  • [21]. K. Messner, B. Vuong, and GK. Tranmer. The Boron Advantage: The Evolution and Diversification of Boron’s Applications in Medicinal Chemistry. Pharmaceuticals,15.3, 264, 2022.
  • [22]. CD. Hunt, Regulation of enzymatic activity: one possible role of dietary boron in higher animals and humans. Biol Trace Elem Res, 205-225, 1998.
  • [23]. CD. Hunt, FH. Nielsen, Interaction Between Boron and Chholecalciferol in the Chicks. Australian Academy of Science. 97, 600. 1981. [24]. FH. Nielsen, Dietary Fat Composition Modifies the Effect of Boron on Bone Characteristics and Plasma Lipids in Rats. Biofactors, 161-171, 2004.
  • [25]. R. Kuru, A. Yarat, Bor ve Sağlığımıza Olan Etkilerine Güncel Bir Bakış. Clin Exp Health Sci, 104-114, 2017.
  • [26]. RJ. Weir, RS. Fisher, Toxicologic studies on borax and boric acid. Toxicol Appl Pharmacol, 351-364. 1972.
  • [27]. JE. Sander, L. Dufour, RD. Wyatt, PB. Bush, RK. Page, Acute toxicity of boric acid and boron tissue residues after chronic exposure in broiler chickens. Avian Dis, 35, 745-749, 1991.
  • [28]. W. Ku, R. Chapin, Mechanism of the testicular toxicity of boric acid in rats: invivo and invitro studies. Environ Health Perspect, 99-105, 1994.
  • [29]. CJ. Price, PL. Strong, FJ. Murray, MM. Goldberg, Blood boron concentrations in pregnant rats fed boric acid throughout gestation. Reported Toxicol, 11, 6, 833-42, 1997.
  • [30]. E. Reagan, Acute dermal toxicity study of sodium tetraboratedecahydrate in New Zealand white rabbits: lab project number: 8403A. Unpublished study prepared by Food & Drug Research Labs, Inc. 9 p. MRID 43553200, 1985.
  • [31]. E. Reagan, Primary eye irritation study of sodium tetraborate decahydrate in New Zealand white rabbits: lab project number: 8403B. Unpublished study prepared by Food & Drug Research Labs, Inc. 21 p. MRID 43553202, 1985.
  • [32]. HM. Dani, HS. Saini, IS. Allag, B. Singh, K. Sareen, Effect of boron toxicity on protein andnucleic acid contents of rat tissues. Res Bull Panjab Univ Sci, 22, 1– 2, 229-235, 1971.
Toplam 31 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Yapısal Biyoloji
Bölüm Derlemeler
Yazarlar

Selcen Çakır 0000-0002-6474-9032

Yayımlanma Tarihi 30 Eylül 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 2 Sayı: 2

Kaynak Göster

IEEE S. Çakır, “Uses of Boron and Boron Toxicity”, Etoxec, c. 2, sy. 2, ss. 115–121, 2022.
 Kapak Resmi İndir