The Dual Effects of Vitamins and Metals: A Review on Health, Mutagenicity, and Antimutagenicity

Yıl 2024, Cilt: 4 Sayı: 2, 73 - 91, 03.10.2024

Eda Delik , Burcu Emine Tefon Öztürk , Bülent Kaya

https://doi.org/10.59838/etoxec.1523001

Öz

Heavy metals and vitamins are substances that have significant impacts on human health. While exposure to heavy metals from environmental and industrial sources leads to toxic effects, vitamins are generally recognised as essential components that support body functions. However, depending on the dose, both groups can be harmful or beneficial to human health. One thing they have in common is that they are both required in trace amounts by the human body. Both heavy metals and vitamins are substances that generally need to be taken into the body from external sources for the metabolism to function properly. This review addresses the toxic and antitoxic effects of heavy metals and vitamins. It also examines the effects of these substances on human health depending on the dose, emphasising both their harmful and beneficial aspects. Important metals and groups of vitamins for health are discussed, emphasizing that high doses can potentially lead to toxicity. As a result, this review presents significant findings to help individuals develop strategies to protect their health and health professionals to manage exposure risks effectively.

Anahtar Kelimeler

antimutagenic, dose, metal, toxicity, vitamin

Vitaminlerin ve Metallerin Çift Yönlü Etkileri: Sağlık, Mutajenite ve Antimutajenite Üzerine Bir İnceleme

Öz

Ağır metaller ve vitaminler insan sağlığı üzerinde önemli etkilere sahip maddelerdir. Çevresel ve endüstriyel kaynaklardan dolayı ağır metallere maruziyet toksik etkilere yol açarken, vitaminler genellikle vücut fonksiyonlarını destekleyen esansiyel bileşenler olarak bilinmektedir. Ancak her iki grup da insan sağlığı açısından doza bağlı olarak zararlı veya yararlı olabilmektedir. İkisinin de ortak noktalarından biri, eser miktarda insan vücudu için gerekli olmalarıdır. Ayrıca hem ağır metaller hem de vitaminler metabolizmanın düzgün yürüyebilmesi için genellikle vücuda dışarıdan alınmaları gereken maddelerdir. Bu derlemede ağır metallerin ve vitaminlerin toksik ve antitoksik etkileri ele alınmıştır. Ayrıca bu maddelerin insan sağlığı üzerindeki etkileri maruz kalınan dozlarla ilişkilendirilerek hem zararlı hem de yararlı yönleri üzerinde durulmuştur. Sağlık için önemli bazı metallere ve vitamin gruplarına değinilerek, yüksek dozların potansiyel toksisite yaratabileceği vurgulanmıştır. Sonuç olarak bu derleme bireylerin sağlığını koruma stratejileri geliştirmelerine ve sağlık profesyonellerinin maruziyet risklerini etkili bir şekilde yönetmelerine yönelik önemli bulgular sunmayı amaçlamıştır.

Anahtar Kelimeler

antimutajenite, doz, metal, toksisite, vitamin

Kaynakça

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