The effect of intravenously given dexketoprofen trometamol on postoperative pain in ovariohysterectomized dogs

Yıl 2014, Cilt: 30 Sayı: 1, 5 - 10, 01.03.2014

Zulfikar Kadir Saritas Musa Korkmaz Oktay Yilmaz

Öz

Aim: The aim of this study was to investigate the postoperative analgesic effect of dexketoprofen trometamol in dogs subjected to ovariohysterectomy.Materials and Methods: Seventeen adult bitches were randomly allocated to two groups. Dexketoprofen trometamol (n=10, 1 mg/kg, IV) was administered to DEX group after recovery of anaesthesia, while those assigned to the control (C) group (n=7) were not given any analgesic after recovery of anesthesia. The ovariohysterectomy procedure was performed on all dogs by the same researcher using a median laparotomy access. Heart rate (HR), respiratory rate (RR) and body temperature were measured during the postoperative period. Pain level was assessed by two researchers 0, 1, 4 and 6 hours after surgery. A modified University of Melbourne Pain Scale (UMPS) was used to evaluate pain in both groups. Results: According to modified UMPS test, postoperative first hour pain score decreased statistically significant (P<0.05) in the DEX group. Although at 6th hour pain scale is lower in DEX group, no significant difference was (P>0.05) determined at other measurement times.Conclusions: The presence of stable vital signs of dexketoprofen administration is a promising finding. Dexketoprofen may used for postoperative pain management in dogs due to its clinical advantage shown by the pain scale.

Anahtar Kelimeler

Dexketoprofen, dog, ovariohysterectomy, postoperative pain

Ovariohisterektomi yapılan köpeklerde intravenöz deksketoprofen trometamol’ün postoperatif ağrı üzerine etkisi

Öz

Amaç: Bu çalışmanın amacı ovariohisterektomi yapılan köpeklerde intravenöz deksketoprofen trometamolün postoperatif ağrı üzerine olan etkisinin araştırılmasıdır. Gereç ve Yöntem: Ergin 17 dişi köpek rastgele iki gruba ayrıldı. Deksketoprofen trametamol (DEX) grubuna (n=10, 1mg/kg, IV) anesteziden uyanma sonrası deksketoprofen trametamol uygulanırken, kontrol (C) grubuna (n=7) herhangi bir analjezik uygulanmadı. Bütün köpeklerin ovariohisterektomileri median laparatomi ile aynı araştırmacı tarafından gerçekleştirildi. Postoperatif periyod süresince kalp frekansı, solunum sayısı ve vücut ısısı ölçüldü. Operasyon sonrası 0, 1, 4 ve 6. saat ağrı düzeyleri iki araştırmacı tarafından değerlendirildi. İki grubun ağrı düzeylerinin değerlendirilmesinde modifiye Melbourne Üniversitesi ağrı skalası (UMPS) kullanıldı.Bulgular: Modifiye UMPS test sonuçlarına göre DEX grubunda postoperatif birinci saat ağrı skorunun istatistiksel olarak önemli derecede (P0.05) belirlenmedi. Öneri: Deksketoprofen uygulamasında vital bulguların stabil olması umut verici bir bulgudur. Ağrı skorunda gösterdiği klinik avantaj ile deksketoprofen köpeklerde postoperatif ağrı kontrolü için kullanım yeri bulabilir.

Anahtar Kelimeler

Deksketoprofen, köpek, ovariohisterektomi, postoperatif ağrı

Kaynakça

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