BUZAĞILARDA SOLUNUM YOLU ENFEKSİYONLARININ TANISINDA BRONKOALVEOLAR LAVAJ SIVISI MUAYENELERİNİN ÖNEMİ

Yıl 2002, Cilt: 18 Sayı: 1, 41 - 51, 01.03.2002

Fatih Mehmet Birdane Veysi Aslan

Öz

Anahtar Kelimeler

Buzağı, Solunum Sistemi Hastalıkları, Bronkoalveolar Lavaj, BAL, Sitoloji, ALP, LDH

The Importance of Bronchoalveolar Lavage Fluid Examinations in the Diagnosis of Respiratory Tract Diseases in Calves

Öz

The present investigation evaluated the changes of cytological constitutents in bronchoalveolar lavage
(BAL) fluid and to detect utility for diagnosis of respiratory disease in calves. For this purpose, 18 calves with acute
respiratory disease, 17 calves with chronic respiratory disease and 11 healthy calves were used as materials. All cal·
ves were examined with regard to clinical examination, complete blood cell counts and BAl fluid anatysis. BAl fluid
was investigated cytologically, biochemically and bacteriologically. BAL fluid lactate dehydrogenase (LOH), alkaline
phosphatase (ALP) activities and total protein (TP) concentrations were significantly higher (IX 0.01) in the calves
with acute and chronic respiratory infection compared to the normal calves. BAl fluid neutrophil percentages were
significantly higher (p< 0.01) in the calves with acute and chronic respiratory infection compared to the normal calves.
Macrophage percentages in BAl fluid were significantly decreased in the calves with acute and chronic respiratory infection.
In the same time, BAL lIuid macrophage percentage was significantly higher in the calves with chronic respiratory
infection compared to that of the calves with acute respiratory infection. The results of this study showed that,
transtracheal BAL fluid analysis was a fast, safe, simple technique producing rapid diagnosis in pneumonic calves.
The diagnostic potential of the percentage of alveolar macrophage and neutrophil counts in BAl fluid were validated.
Cytologic examination of the respiratory tract may provide a etiopathotogic diagnosis or information for improved case
management, until more complex diagnostic procedures are performed.

Anahtar Kelimeler

Calf, Respiratory Disease, Bronchoalveolar Lavage Fluid, BAL, Cytology, ALP, LDH