Unilateral Grave's Disease: A case report

Öz

Graves' disease is a a rare autoimmune thyroid disease that characterized by hyperthyroidism, diffuse goiter, infiltrative ophthalmopathy, infiltrative dermopathy and thyroid akropachy. It usually affects both lobes of the thyroid, unilateral involvement have been reported rarely. In our clinic we diagnosed unilateral graves disease wich has single-sided involvement (in other thyroid lobe and isthmus agenesis-hemiagenesis) in cintigraphy. Thus we presented a rare unilateral graves case with current literature.

Anahtar Kelimeler

• Unilateral graves, Thyroid hemiagenesis, Hyperthyroidism.

Unilateral Grave's Hastalığı: Olgu sunumu

Öz

Graves hastalığı; hipertiroidi, diffüz guatr, infiltratif oftalmopati, daha nadir olarak infiltratif dermatopati ve tiroid akropatisi ile karekterize otoimmün bir tiroid hastalığıdır. Genellikle her iki tiroid lobunu da etkilemesine rağmen, tek taraflı tutulum nadir olarak bildirilmiştir. Kliniğimizde tanı konulan, sintigrafide tek taraflı tutulum gösteren (diğer lob ve isthmus agenezik-tiroid hemiagenezisi) nadir görülen bir olgu olan unilateral graves hastalığı güncel literatür eşliğinde sunulmuştur.

Anahtar Kelimeler

• Unilateral graves, Tiroid hemiagenezisi, Hipertiroidi.

Kaynakça

1. Weetman AP. Graves' disease. N Engl J Med 2000; 343: 1236
2. Cooper DS. Hyperthyroidism. Lancet 2003; 362: 459-68. O’Donnell AL. Hyperthyroidizm:Systemic Effects and Differential Diagnosis. Falk SE. Thyroid Disease: Second Edition. Lippincott Raven. Philadelphia 1997; 14: 241-52.
3. Uysal AR. Tirotoksikoz ve Hipertiroidizm. İşgör A (ed). Tiroid Hastalıkları ve Cerrahisi. Avrupa Tıp Kitapçılık, İstanbul. 2000; 6: 299-324.
4. Bolognesi M, Rossi R. Unilateral Graves’ disease. Thyroid 2006; 16: 493-95.
5. Sakata S, Fuwa Y, Goto S. Two cases of Graves’ disease with presentation of unilateral diffuse uptake of radioisotopes. J Endocrinol Invest 1993; 16: 903-7.