BibTex RIS Kaynak Göster

The Incidence of Histopathologic Diagnosis in Hysterectomy Specimens

Yıl 2012, Cilt: 17 Sayı: 1, 19 - 22, 01.02.2012
https://izlik.org/JA54XY22KZ

Öz

Objective: This study identified the frequency of clinical indications for hysterectomy and the most common pathologies in hysterectomy specimens. Material and Methods: A total of 361 hysterectomy specimens between October 2007 and October 2009 were retrieved and studied Results: The most common indication for hysterectomy was leiomyoma (31.85 %). Other indications were endometrial hyperplasia (27.14 %), dysfunctional uterine bleeding (18.55 %), uterine prolapse (9.14 %), chronic pelvic pain (7.20 %), adenomiyosis (3.87 %), cervical neoplasia (2.21 %). The most common pathology identified was leiomyoma (40.16 %). Other pathologies included endometrial hyperplasia (38.22 %), adenomyosis (25.48 %), endometrial polyps (8.86 %), CIN 1 (3.32 %), CIN 2 (1.66 %) and atrophic endometrium (3.60 %). In 158 (43.76 %) of hysterectomy specimens combined pathology was identified. The most common combination was leiomyoma and endometrial hyperplasia (38.60%). Other combined pathologies included adenomoysis and endometrial polyps (17.72 %), adenomyosis and leiomyoma (12.65 %), leiomyoma and endometrial polyps (8.22 %). Conclusion: The existence of cervical disorders should be demonstrated when an operation is going to be performed for an endometrial pathology in a pre or postmenopausal woman. Cervix and cervical canal should be examined during endometrial evaluation.

Kaynakça

  • Lee NC, Dicker RC, Rubin GL, Ory HW. Confirmation of the preoperative diagnoses for hysterectomy. Am J Obstet Gynecol 1984; 150: 283-287.
  • Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update 1998; 4: 312-322.
  • Leyendecker G, Wildt L, Mall G. The pathophysiology of endometriosis and adenomyosis: tissue injury and repair. Arch Gynecol Obstet 2009; 280: 529-538.
  • Bird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterus-revisited. Am J Obstet Gynecol 1972; 112: 583-593.
  • K. Jo. Adenomyosis: the pathophysiology of an oestrogen- dependent disease. Best Pract Res Clin Obstet Gynecol 2006; 20: 493-502.
  • Atri M, Reinhold C, Mehio AR, Chapman WB, Bret PM. Adenomyosis: US features with histologic correlation in an in vitro study. Radiology 2000; 215: 783-790.
  • Flake GP, Andersen J, Dixon D. Etiology and pathogenesis of uterine leiomyomas: a review.Environ Health Perspect 2003; 111: 1037- 1054.
  • Sherman ME, Mazur MT, Kurman RJ. Benign diseases of the endometrium. In: Kurman RJ, editor. Blaunstein’s pathology of the female genital tract. 5. edition. New York: Springer, 2002; 421–466.
  • Perez-Medina T, Martinez O, Folgueira G, Bjo J. Which endometrial polyps should be resected? J Am Assoc Gynecol Laparosc 1999; 6: 71-74.
  • Reslova T, Tosner J, Resl M, Kugler R, Vavrova I. Endometrial polyps. A clinical study of 245 cases. Arch Gynecol Obstet 1999; 262: 133-139.
  • Talukder SI, Haque MA, Hug MH, Alam MO, Roushan A, Noor Z, et al. Histopathological analysis of hysterectomy specimens. Mymensing Med J 2007; 16: 81-84.
  • Bukhari U, Sadiq S. Analysis of the underlying pathological lesions in hysterectomy specimens. Pak J Pathol 2007; 18: 110-112.
  • Verit FF, Artuc H, Kafalı H. The evaluation Of Simple Hysterectomies At Harran University Department Of Obstetrics And Gynecology. Türkiye Klinikleri J Gynecol Obst 2006; 16: 77-81.
  • Sutton GP, Brill L. Malignant papillary lesion of the endometrium. Gynecol Oncol 1987; 27: 294-304.
  • Kurman RJ, Kaminski PF, Norris HJ. The behavior of endometrial hyperplasia. A long term study of 'untreated' hyperplasia in 170 patients. Cancer 1985; 56: 403-412.
  • Tabata T, Yamawaki T, Yabana T, Ida M, Nishimura K, Nose Y. Natural history of endometrial hyperplasia: study of 77 patients. Arch Gynecol Obstet 2001; 265: 85-88.
  • Janicek MF, Rosenshein NB. Invasive endometrial cancer in uteri resected for atypical endometrial hyperplasia. Gynecol Oncol 1994; 52: 373-378.
  • Gönderilme Tarihi: 08.08.2011

Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı

Yıl 2012, Cilt: 17 Sayı: 1, 19 - 22, 01.02.2012
https://izlik.org/JA54XY22KZ

Öz

Amaç: Bu çalışmada histerektomi için klinik endikasyonların sıklığı ve histerektomi materyallerindeki en yaygın patolojiler tanımlandı. Gereç ve Yöntem: Ekim 2007 ile Ekim 2009 arasında 361 histerektomi materyali tekrar gözden geçirildi ve patolojik tanılar araştırıldı. Bulgular: Histerektomi için en yaygın klinik endikasyon leiomyoma (% 31.85) idi. Diğer klinik endikasyonlar endometrial hiperplazi (% 27.14), disfonksiyonel uterin kanama (% 18.55), uterus prolapsusu (% 9.14), kronik pelvik ağrı (% 7.20), adenomyozis (% 3.87), servikal neoplazi (% 2.21) idi. En yaygın tanımlanan patoloji leiomyoma (% 40.16) idi. Diğer patolojiler endometrial hiperplazi (% 38.22), adenomyozis (% 25.48), endometrial polipler (% 8.86), CIN 1 ( % 3.32 ), CIN 2 ( % 1.66 ) ve atrofik endometrium (% 3.60) idi. Yüzellisekiz (% 43.76) histerektomi materyalinde kombine patolojiler tanımlandı. En yaygın kombinasyon leiomyoma ve endometrial hiperplazi (% 38.60) idi. Diğer kombine patolojiler adenomyozis ve endometrial polip (% 17.72), adenomyozis ve leiomyoma (% 12.65), leiomyoma ve endometrial polipler (% 8.22) idi. Sonuç: Endometrial patolojiler nedeniyle özellikle premenapozal ve postmenapozal dönemde opere edilecek olgularda servikal neoplazilerin beraber olabileceği unutulmamalıdır. Bu nedenle endometrial örnekleme yaparken endoservikal örneklemeninde yapılması önemlidir.

Kaynakça

  • Lee NC, Dicker RC, Rubin GL, Ory HW. Confirmation of the preoperative diagnoses for hysterectomy. Am J Obstet Gynecol 1984; 150: 283-287.
  • Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update 1998; 4: 312-322.
  • Leyendecker G, Wildt L, Mall G. The pathophysiology of endometriosis and adenomyosis: tissue injury and repair. Arch Gynecol Obstet 2009; 280: 529-538.
  • Bird CC, McElin TW, Manalo-Estrella P. The elusive adenomyosis of the uterus-revisited. Am J Obstet Gynecol 1972; 112: 583-593.
  • K. Jo. Adenomyosis: the pathophysiology of an oestrogen- dependent disease. Best Pract Res Clin Obstet Gynecol 2006; 20: 493-502.
  • Atri M, Reinhold C, Mehio AR, Chapman WB, Bret PM. Adenomyosis: US features with histologic correlation in an in vitro study. Radiology 2000; 215: 783-790.
  • Flake GP, Andersen J, Dixon D. Etiology and pathogenesis of uterine leiomyomas: a review.Environ Health Perspect 2003; 111: 1037- 1054.
  • Sherman ME, Mazur MT, Kurman RJ. Benign diseases of the endometrium. In: Kurman RJ, editor. Blaunstein’s pathology of the female genital tract. 5. edition. New York: Springer, 2002; 421–466.
  • Perez-Medina T, Martinez O, Folgueira G, Bjo J. Which endometrial polyps should be resected? J Am Assoc Gynecol Laparosc 1999; 6: 71-74.
  • Reslova T, Tosner J, Resl M, Kugler R, Vavrova I. Endometrial polyps. A clinical study of 245 cases. Arch Gynecol Obstet 1999; 262: 133-139.
  • Talukder SI, Haque MA, Hug MH, Alam MO, Roushan A, Noor Z, et al. Histopathological analysis of hysterectomy specimens. Mymensing Med J 2007; 16: 81-84.
  • Bukhari U, Sadiq S. Analysis of the underlying pathological lesions in hysterectomy specimens. Pak J Pathol 2007; 18: 110-112.
  • Verit FF, Artuc H, Kafalı H. The evaluation Of Simple Hysterectomies At Harran University Department Of Obstetrics And Gynecology. Türkiye Klinikleri J Gynecol Obst 2006; 16: 77-81.
  • Sutton GP, Brill L. Malignant papillary lesion of the endometrium. Gynecol Oncol 1987; 27: 294-304.
  • Kurman RJ, Kaminski PF, Norris HJ. The behavior of endometrial hyperplasia. A long term study of 'untreated' hyperplasia in 170 patients. Cancer 1985; 56: 403-412.
  • Tabata T, Yamawaki T, Yabana T, Ida M, Nishimura K, Nose Y. Natural history of endometrial hyperplasia: study of 77 patients. Arch Gynecol Obstet 2001; 265: 85-88.
  • Janicek MF, Rosenshein NB. Invasive endometrial cancer in uteri resected for atypical endometrial hyperplasia. Gynecol Oncol 1994; 52: 373-378.
  • Gönderilme Tarihi: 08.08.2011
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Yazarlar

Remzi Atılgan Bu kişi benim

Abdullah Boztosun Bu kişi benim

Mehmet Reşat Özercan Bu kişi benim

Yayımlanma Tarihi 1 Şubat 2012
IZ https://izlik.org/JA54XY22KZ
Yayımlandığı Sayı Yıl 2012 Cilt: 17 Sayı: 1

Kaynak Göster

APA Atılgan, R., Boztosun, A., & Özercan, M. R. (2012). Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı. Fırat Tıp Dergisi, 17(1), 19-22. https://izlik.org/JA54XY22KZ
AMA 1.Atılgan R, Boztosun A, Özercan MR. Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı. Fırat Tıp Dergisi. 2012;17(1):19-22. https://izlik.org/JA54XY22KZ
Chicago Atılgan, Remzi, Abdullah Boztosun, ve Mehmet Reşat Özercan. 2012. “Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı”. Fırat Tıp Dergisi 17 (1): 19-22. https://izlik.org/JA54XY22KZ.
EndNote Atılgan R, Boztosun A, Özercan MR (01 Şubat 2012) Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı. Fırat Tıp Dergisi 17 1 19–22.
IEEE [1]R. Atılgan, A. Boztosun, ve M. R. Özercan, “Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı”, Fırat Tıp Dergisi, c. 17, sy 1, ss. 19–22, Şub. 2012, [çevrimiçi]. Erişim adresi: https://izlik.org/JA54XY22KZ
ISNAD Atılgan, Remzi - Boztosun, Abdullah - Özercan, Mehmet Reşat. “Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı”. Fırat Tıp Dergisi 17/1 (01 Şubat 2012): 19-22. https://izlik.org/JA54XY22KZ.
JAMA 1.Atılgan R, Boztosun A, Özercan MR. Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı. Fırat Tıp Dergisi. 2012;17:19–22.
MLA Atılgan, Remzi, vd. “Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı”. Fırat Tıp Dergisi, c. 17, sy 1, Şubat 2012, ss. 19-22, https://izlik.org/JA54XY22KZ.
Vancouver 1.Remzi Atılgan, Abdullah Boztosun, Mehmet Reşat Özercan. Histerektomi Materyallerinde Histopatolojik Tanıların İnsidansı. Fırat Tıp Dergisi [Internet]. 01 Şubat 2012;17(1):19-22. Erişim adresi: https://izlik.org/JA54XY22KZ