Granular cell tumor of the Urinary bladder: Case Report

Yıl 2010, Cilt: 15 Sayı: 4, 207 - 209, 01.08.2010

Dalia Hammoud Mazen Shaheen Lisa Le Chimezie Amanambu

Öz

Granular cell tumors (GCT) are extremely rare lesions of the urinary bladder with only 12 cases have been reported in the literature. Although usually benign, these lesions are commonly confused for malignant tumors since they may present as solid tumors with ill defined margins and ulcerating surface and hence could be confused with transitional, squamous cell carcinoma or sarcoma in the urinary bladder. Only two cases of malignant granular cell tumor of the urinary bladder were reported. A careful pathologic assessment for establishing the appropriate diagnosis is required and the treatment is either a conservative or aggressive surgical treatment for benign or localized malignant GCT of the urinary bladder, respectively. We report the case of a forty six year old patient who had benign GCT of the urinary bladder.

Anahtar Kelimeler

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İdrar Kesesinin Granüler hücreli tümörü: Olgu Sunumu

Öz

Granüler hücreli tümörler (GHT) literatürde sadece 12 adet olgu sunumu ile belirtilmiş olan idrar kesesinin oldukça nadir görülen lezyonlarıdır. Genellikle iyi huylu olmalarına rağmen bu tümörler kötü huylu tümörler ile karışabilir. Çünkü bu lezyonlar idrar kesesinde sarkom veya transizyonel skuamöz hücreli kanseri ile karışabildiklerinden dolayı yüzeyleri ülserleşmiş ve sınırları düzensiz solid tümörler olarak görülebilir. İdrar yollarının kötü huylu granüler hücreli tümörü sadece iki olguda bildirilmiştir. Uygun tanıyı koyabilmek için dikkatli bir patolojik değerlendirme gereklidir. İyi huylu tümörlerin tedavisi semptomatik koruyucu tedavi iken, kötü huylu tümörlerin tedavisi cerrahidir. İdrar kesesinde iyi huylu granüler hücreli tümörü olan kırk altı yaşındaki bir hastayı olgu sunumu olarak bildiriyoruz.

Anahtar Kelimeler

Granüler hücreli tümör, idrar kesesi, S100 proteini, immünohistokimya

Kaynakça

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