Solitary Tracheal Neurofibroma: Case Report and Literature Review

Yıl 2008, Cilt: 13 Sayı: 3, 228 - 231, 01.06.2008

Nusret Akpolat Sultan Pehlivan A. Eraslan Balcı

Öz

Tracheal neurofibroma (TN) is a slow-growing benign tumor, which can be confused with malignant tumors of the trachea clinically, radiologically and macroscopically. Tracheal location of solitary neurofibromas is extremely rare, with only 18 cases reported hitherto. A 65-year-old male case was admitted to the emergency department in January 2005, complaining of shortness of breath both at rest and on effort, expectorating sputum and cough continuing for 15 days. The patient, whose mass was totally excised, was diagnosed as “solitary tracheal neurofibroma”. TN, which is usually accompanied with NF1, has very rare solitary forms. We aimed to discuss this case in the light of literature data, due to its being rare and posing a distinctive diagnosis problem.©2008, Firat University, Medical Faculty.

Anahtar Kelimeler

-

Soliter Trakeal Nörofibrom: Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Öz

Trakeal nörofibrom (TN), yavaş büyüyen, klinik, radyolojik ve makroskobik olarak trakeanın malign tümörleri ile karışabilen benign bir tümördür. Soliter nörofibromların trakeal yerleşimi oldukça nadir olup bu güne kadar bildirilen olgu sayısı 18' dir. Olgu 65 yaşında erkek hasta, 15 gündür devam eden, efor ve istirahatle gelen nefes darlığı, balgam çıkarma, öksürük yakınmaları ile acil servise başvurdu. Hastada endotrakeal kitle saptandı. Kitlesi total eksize edilen hastaya “soliter trakeal nörofibrom” tanısı kondu. TN genellikle NF1 ile birlikte olup soliter formları oldukça nadir görülmektedir. Olgunun nadir görülmesi ve ayırıcı tanı problemi oluşturması nedeni ile literatür eşliğinde tartışmayı amaçladık.©2008, Fırat Üniversitesi, Tıp Fakültesi.

Anahtar Kelimeler

Trakea, Soliter Nörofibrom

Kaynakça

• 1. Grillo HC, Mathisen DJ. Primary tracheal tumors: treatment and results. Ann Thorac Surg 1990; 49: 69-77.
• 2. Rosai J. Respiratory tract In: Rosai J, Ackerman LV (Editors). Ackerman’s Surgical Pathology. 9th ed. St. Louis: Mosby-Year Book, 2004:335-350
• 3. Gaissert HA, Grillo HC, Shadmehr B et al. Uncommon primary tracheal tumors. Ann Thorac Surg 2006; 82: 268-273.
• 4. Goldblum JR, Weiss SW. Benigns tumors of the peripheral nerves. In: Goldblum JR, Weiss SW (Edıtors). Soft Tissue Tumors, 2th edn, St Louis: The CV Mosby Company, 2001: 1122–1146.
• 5. Han- Shui Hsu, Chien- Ying Wang, Wing – Yin Li et al. Endotracheobronchial neurofibromas. Ann Thorac Surg 2002; 74:1704-1706.
• 6. Mıettınen M. Nevre sheath tumors. In: Mıettınen M (Editors). Diagnostic Soft Tissue Pathology, 1st edn, Philadelphia: Pennsylvania, 2003: 347-353.
• 7. Ide F, Shimoyama T, Horie N et al. Comparative ultrastructural and immunohistochemical study of perineurioma and neurofibroma of the oral mucosa. Oral Oncol 2004; 40: 948-953
• 8. Yamamoto T, Maruyama S, Mizuno K. Schwannomatosis of the sciatic nevre. Skeletal Radiol 2001; 30: 109-113.
• 9. Ishida T, Kuroda M, Motoi T, et al. Phenotypic diversity of neurofibromatosis 2: association with plexiform schwannoma . Histopathology 1998; 32: 264-270.
• 10. Suziki H, Sekine Y, Motohashı S et al. Endobronchial neurogenic tumors treated by transbronchial electrical snaring and Nd-YAG laser abrasion: report of three cases. Surg Today 2005; 35: 243- 246.
• 11. Refael- Y, Weissberg- D. Surgical managemant of tracheal tumors. Ann Thorac Surg 1997; 64:1429-1432.
• 12. Cranshaw J.H, Morgan C, Knowles G et al. Intramural neurofibroma of the trachea treated by multiple stents.Thorax 2001; 56: 583-584.
• 13. Low SY, Eng P, Thirugnanam A. Primary endotracheal neurogenic tumors. Surg Endosc 2004; 18: 348.
• 14. Chen PT, Chang WK, Hsu WH et al. Anesthetic management of a pat,ent undergoing segmental resection of trachea with an endotracheal neurofibroma and nearly total occlusion of trachea. Acta Anaesthesiol Taiwan 2004; 42: 223-233