Gaint Haematoma After Pilonidal Sinus Operation Due To Factor VII Deficiency: A Case Report

Yıl 2007, Cilt: 12 Sayı: 2, 132 - 134, 01.04.2007

Öner Menteş Oral Nevruz Ergun Bozoğlu Zeki Çankır Ömer Özgül Mustafa Özdemir

Öz

Pilonidal sinus disease is usually occurs in the intergluteal region. Many surgical techniques have been described for treatment of this disease. A main surgical complication after operation is infection, while haematoma, on the other hand, is a rare complication. Factor VII deficiency is an uncommon bleeding disorder with an estimated incidence of 1/500.000. We report a case with giant haematoma 2 years after pilonidal sinus operation with out any trauma. Heterozigot Factor VII deficiency is diagnosed with laboratory tests. The patient was discussed in the view of the literature knowledge. ©2007, Firat University, Medical Faculty

Anahtar Kelimeler

-

Pilonidal Sinus Cerrahisi Sonrası Faktör VII Eksikliği Nedeniyle Geç Dönemde Ortaya Çıkan Dev Hematom: Olgu Sunumu

Öz

Pilonidal sinüs hastalığı intergluteal bölgede oluşan hastalıktır. Tedavisi için pek çok cerrahi yöntem tanımlanmıştır. Cerrahi sonrası en çok karşılaşılan komplikasyon enfeksiyondur. Geç dönemde hematom oluşumu çok ender rastlanan komplikasyondur. Faktör VII eksikliği, 1/500.000 gibi oldukça ender görülen doğumsal kanama diatezi nedenlerinden birisidir. Bu yazıda pilonidal sinüs hastalığı nedeniyle primer eksizyon ve kapama operasyonu olan hastada travma olmaksızın iki yıl sonra gelişen dev hematom saptanması ve yapılan tetkiklerinde heterozigot Faktör VII eksikliği tanısı konulan olgu literatür eşliğinde tartışılarak sunuldu. ©2007, Fırat Üniversitesi, Tıp Fakültesi

Anahtar Kelimeler

Pilonidal sinüs hastalığı, hematom, Faktör VII eksikliği

Kaynakça

• Hull TL, Wu J Pilonidal disease. Surg Clin North Am 2002; 82: 1169-1185.
• Spivak H, Brooks V, Nussbaum M, Friedman I: Treatment of Chronic Pilonidal Disease. Dis Colon Rectum 1996; 39: 1136- 1139.
• Al Jaberi M R. Excision and simple primary closure of choronic pilonidal sinus: Eur J Surg 2001; 167: 133-135.
• Perry D J: Factor VII Deficiency. British Journal Haematology 2002; 118: 689-700.
• Chintapatla S, Safarini N, Kumar S, Haboubi N: Sacrococygeal pilonidal sinus: Historical review, pathological insight and surgical options. Tech coloproctol 2003; 7: 3-8.
• Mersh-Allen T. Pilonidal sinus: finding the right track for treatment. Br J Surg 1990; 77: 123-132.
• Petersen S, Koch R, Stelzner S, Wendlandt T, Ludwig K: Primary closure technics in choronic pilonidal sinus. A survey of the results of different surgical approaches. Dis Colon Rectum 2002; 45: 1458-1467.
• Bascom J. Pilonidal disease: Long term results of follicle Removal. Dis Colon Rectum 1983; 26: 800-807.
• Peyvandi F, Mannucci M, Abdoullahi M, Dı Rocco N, Sharifian R. Clinical manifestations in 28 Italian and Iranian patients with severe Factor VII Deficiency. Haemophilia 1997; 3: 242-246.
• Yuste-Jimenez V, Villar A, Morado M, etal. Continous infusion of recombinant activated Factor VII during caesarean delivery in a patient with congenital Factor VII deficiency. Haemophilia. 2000; 6:588-590.
• Arbini A, Pollak E, Beylaran K, High K, Bauer K. Severe Factor VII deficiency due to a mutation disrupting a hepatocyte nuclear factor 4 binding site in the Factor VII promoter: Blood 1997; 89: 176-182.
• Kaiser C, Mcauliffe J, Barth R, Lynch J: Hypoprothrombinemia and hemorrhage in a surgical patient treated with cefotetan: Arch Surg 1991; 126: 524-525.
• Carew JA., Pollak ES., LopaciukS, Bauer KA.: A new mutation in the HNF4 binding region of the factor VII promoter in a patent with severe Factor VII deficiency: Blood 2000; 96: 4370-4372.
• Morrissey JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated Factor VII levels in plasma using a tissue factor Mutant selectivity Deficient in Promoting Factor VII activation. Blood 1993; 81: 734-744.
• Cohen A, Edmondson R, Phillips M, Ward V, Kakkar V. The changing pattern of venous thromboembolic disease: Haemostasis 1996; 26: 65-71.
• Tagariello G, Biasi E, Gajo B, etal. Recombinant Factor VIIa (Novoseven) continuous infusion and total hip replacement in patients with haemophilia and high titre of inhibitors to FVIII: experience of two cases. Haemophilia 2000; 6: 581-583.
• Kabul Tarihi: 29.09.2006