Nephrotic Syndrome in a Child Following a Bee Sting

Yıl 2006, Cilt: 11 Sayı: 1, 71 - 72, 01.02.2006

Mustafa Aydın Nimet Kabakuş Saadet Akarsu Mustafa Demirol

Öz

Bee stings have previously been implicated in the development of nephrotic syndrome, though the reported cases in the literature are poorly documented. A three-years-old girl developed generalized edema eight days after a bee sting. The physical examination and laboratory findings were relevant with nephrotic syndrome. Her serum IgE level was to be increased. Prompt remission with resolution of edema and normalization of the laboratory findings was obtained after given the corticosteroid treatment. Due to existence of association between development of nephrotic syndrome and hypersensitivity, cases of bee sting must be closely followed-up for multiple immune-mediated complications. ©2006, Fırat Üniversitesi, Tıp Fakültesi

Anahtar Kelimeler

-

Arı Sokması Sonrası Gelişen Nefrotik Sendrom Olgusu

Öz

Arı sokmaları daha önceleri nefrotik sendromun bir nedeni olarak suçlanmış olmakla birlikte, literatürde fazla sayıda olgu bildirilmemiştir. Üç yaşında kız olgu arı sokmasından sekiz gün sonra gelişen yaygın ödemleri nedeni ile başvurdu. Fizik muayene ve laboratuvar bulguları nefrotik sendrom ile uyumlu idi. Serum IgE düzeyi yüksek bulundu. Kortikosteroid tedavisinden sonra ödemlerinin hızla gerilediği ve laboratuvar bulgularının ise normale geldiği görüldü. Nefrotik sendrom gelişimi ve aşırı duyarlılık arasında ilişki olması nedeni ile arı sokması vakaları gelişebilecek bir çok immün-aracılı komplikasyonlar yönünden yakından izlenmelidir. ©2006, Fırat Üniversitesi, Tıp Fakültesi

Anahtar Kelimeler

Nefrotik sendrom, arı sokması, çocuk

Kaynakça

• Velibor T. Nephrotic syndrome in a child after a bee sting. Pediatr Nephrol 2000; 15: 245-247.
• Florido JF, Diaz Pena JM, Belchi J, Estrada JL, Garcia Ara MC, Ojeda JA. Nephrotic syndrome and respiratory allergy in childhood. J Investig Allergol Clin Immunol 1992; 2: 136-140.
• Schnaper HW. The immune system in minimal change nephrotic syndrome. Pediatr Nephrol 1989; 3: 101-110.
• Fontana VJ, Spain WC, Desanctis AG. The role of allergy in nephrosis. N Y State J Med 1956; 56: 3907-3910.
• Hardwicke J, Soothill JF, Squire JR, Holti G. Nephrotic syndrome with pollen hypersensitivity. Lancet 1959; 1: 500-502.
• Sandberg DH, McIntosh RM, Bernstein CW, Carr R, Strauss J. Severe steroid-responsive nephrosis associated with hypersensitivity. Lancet 1977; 1: 388-391.
• Meadow SR, Sarsfield JK. Steroid-responsive neprotic syndrome and allergy: clinical studies. Arch Dis Child 1981; 56: 509-516.
• Shishkin AN. The role of immediate-type allergic reactions in the pathogenesis of the nephrotic syndrome. Ter Arkh 1996; 68: 19- 21.
• Meadow SR, Sarsfield JK, Scott DG, Rajah SM. Steroid- responsive neprotic syndrome and allergy: immunological studies. Arch Dis Child 1981; 56: 517-524.
• Arkwright PD, Clark G. Infantile nephrotic syndrome and atopy. Pediatr Nephrol 1996; 10: 509-510.
• Olivero JJ, Ayus JC, Eknoyan G. Nephrotic syndrome developing after bee stings. South Med J 1981; 74: 82-83.
• Elming H, Solling K. Urine protein excretion after Hymenoptera sting. Scand J Urol Nephrol 1994; 28: 13-15.
• Cuoghi D, Venturi P, Cheli E. Bee sting and relapse of nephrotic syndrome. Child Nephrol Urol 1988-89; 9: 82-83.
• Tauk B, Hachem H, Bastani B. Nephrotic syndrome with mesangial proliferative glomerulonephritis induced by multiple wasp stings. Am J Nephrol 1999; 19: 70-72.
• Zaman F, Saccaro S, Latif S, Atray N, Abreo K. Minimal change glomerulonephritis following a wasp sting. Am J Nephrol 2001; 21: 486-489.
• Kabul Tarihi: 23.10.2005