LOKAL OTOJEN OSTEOKONDRAL GREFT UYGULAMALARI: KÖPEKLERDE DİZ EKLEMİNDE DENEYSEL ÇALIŞMA

Yıl 2008, Cilt: 6 Sayı: 3, 72 - 77, 31.07.2008

Ali Said Durmuş , Yesari Eröksüz

Öz

Yapılan
bu çalışmanın amacı köpeklerde diz eklemindeki osteokondral defektlerin
onarımında lokal otojen osteokondral greftlerin uygulanabilirliğini
araştırmaktı.

 

Çalışmada
18 adet sağlıklı, yetişkin melez köpek kullanıldı. Osteokondral defektler,
standart silindir biçimin-de (0.5 cm x 0.5 cm) femurun lateral ve medial
kondyluslarının her ikisinde de oluşturuldu. Oluşturulan defektler 9 köpekte
(tedavi grubu) femoral trochlea’nın lateral ve medial kısımlarının üst yüzeylerinden
elde edilen otojen osteokondral greftlerle dolduruldu. Dokuz köpek ise kontrol
grubu olarak tutuldular.

 

Klinik
ve radyolojik kontroller 15 gün aralıklarla gerçekleştirildi. Histopatolojik
kontroller ise 15, 30 ve 60. günlerde gerçekleştirildi.

 

Sonuç
olarak, bulgular köpeklerin diz eklemindeki osteokondral defektlerin, lateral
ve medial femoral trochlea’nın üst kısımlarından elde edilen otojen
osteokondral greftlerle sağaltımlarının gerçekleştirilebilece-ğini göstermiştir.

Anahtar Kelimeler

Otojen Osteokondral Greft, Köpek

LOCAL AUTOGENOUS OSTEOCHONDRAL GRAFT APPLICATIONS: AN EXPERIMENTAL STUDY IN DOGS KNEE JOINTS

Öz

The
aim of this study was to investigate applicability
of local autogenous osteochondral grafts for the repairment of osteochondral
defects in knee joints of dogs.

 

The
material consisted of 18 healthy adult mongrel dogs. Osteochondral defects in
standard cylindrical shape (0.5 cm x 0.5 cm) were created on both lateral and
medial femoral condyles.The defects were filled with autogenous osteochondral
grafts harvested from upper surface of lateral and medial labium of femoral
trochlea in treatment group (9 dogs). Nine dogs were kept as control group.

 

Clinical
and radiographical evaluations were carried out at the 15 days intervals.
Histopathological examinations were carried out at the 15^th, 30^th
and 60^th days in each group.

 

Consequently,
the results indicated that autogenous osteochondral grafts harvested from upper
surface of lateral and medial labium of femoral trochlea could be applied in
treatment of osteochondral defects in knee joints of dogs.

Anahtar Kelimeler

Autogenous Osteochondral Graft, Dog

Kaynakça

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