Fat mass lipid profile and relations to bone mineral density

Öz

Various studies have examined bone mineral density and its relation to fat mass, but arrived at contradictory results. Our study were planned to evaluate the connection between bone mineral density, serum lipid profile and fat mass. Total fat mass and bone mineral density were measured by dual energy x-ray absorptiometry in 29 women. Serum lipid profile was also evaluated by routine biochemical methods. Total fat mass, cholesterol, trigiiserid, LDL, VLDL levels were higher and HDL level were lower in patients with t score < -2.5 than in 16 patients with t score > -1.5. Furthermore, cholesterol level was negatively correlated with bone mineral density'and positively correlated with fat mass and percent fat. According to our results, serum total cholesterol .level was higher in patients with higher total fat mass and bone mineral density was lover in patients with hypercholesterolemia.

Anahtar Kelimeler

• -

Vücut total yağ kitlesi ve lipid profilinin kemik mineral yoğunluğu île ilişkisi

Öz

Kemik mifıeidi yoğunluğu ile yay doku ve Set un ı ku'ıeblerui düzeyi arasındaki ilişki çok sayıda araştırmaya konu olmuş ancak farklı sonuçlar bildirilmiştir. Çalışmamız, kemik mineral yoğunluğunun serum lipid profili ve toplam yağ doku kitlesi ile ilişkisinin araştırılması amacıyla planlandı. Toplam 29 kadında dual enerji x-ray absorbsiyometri yöntemiyle ölçülen kemik mineral yoğunluğu, toplam yağ doku kitlesi ve serum lipid profili değerlendirildi. T skoru -2.5 ve altında olan 13 kadında t skoru -1.5 ve üzerinde olan 16 kadına göre yağ kitlesi, kolesterol, trigiiserid, LDL, VLDL değerleri daha yüksek, HDL değeri daha düşük bulundu. Ayrıca kolesterol düzeyi KMY değeri ile negatif, yağ kitlesi ve yağ oranı ile pozitif ilişki gösteriyordu. Bu sonuçlara göre vücut toplam yağ kitlesi fazla olan hastalarda kolesterol düzeyinin daha yüksek ve kolesterol düzeyi yüksek olan hastalarda kemik mineral yoğunluğunun daha düşük olduğu ve özellikle menapoz sonrası dönemde hiperlıpideminin kardiyovasküler hastalıkların yanı sıra osteoporoz için de bir risk faktörü olabileceği düşünülebilir.

Anahtar Kelimeler

• Kemik mineral dansitesi, Kolesterol, Yað kitlesi

Kaynakça

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