Cutaneous lymphoid hyperplasia: a case report

Öz

Cutaneous lymphoid hyperplasia (CLH), occurring as a result of various antigenic stimuli, is considered as a process of reactive lymphoid and may have potential for progression to overt lymphoma. CLH lesions may resemble lymphoma both clinically and histologically. We present a case of a 24-year-old man who spontaneously developed lesions of unknown cause consistent with cutaneous lymphoid hyperplasia. Thus, in this study we discuss the etiology, clinical features, diagnosis, and management of CLH and also review the literature.

Anahtar Kelimeler

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Kutanöz lenfoid hiperplazi: olgu sunumu

Öz

Kutanöz lenfoid hiperplazi (KLH) çeşitli antijenik uyarılar sonucu gelişen selim lenfoid reaktif bir dermatozdur. Lenfomaya dönüşüm potansiyeli de bulunabilen KLH lezyonları hem klinik hem de histopatolojik olarak lenfomaya benzeyebilir. Makalemizde spontan olarak gelişen, sebebi belli olmayan KLH'li 24 yaşında bir erkek olgu vesilesiyle KLH'nin etiyolojisi, klinik özellikleri, tanı ve tedavisi tartışılmaktadır.

Anahtar Kelimeler

• Kutanöz, lenfoid, hiperplazi

Kaynakça

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3. 3. de Diego J, Berridi D, Saracibar N, Requena L. Cutaneous pseudolymphoma in association with molluscum contagiosum. Am J Dermatopathol 1998;20(5):518-21.
4. 4. Nihal M, Mikkola D, Horvath N, Gilliam AC, Stevens SR, Spiro TP, et al. Cutaneous lymphoid hyperplasia: a lymphoproliferative continuum with lymphomatous potential. Hum Pathol 2003;34(6):617-22.
5. 5. Cheuk W, Lee KC, Chong LY, Yuen ST, Chan JK. IgG4-related sclerosing disease: A potential new etiology of cutaneous pseudolymphoma. Am J Surg Pathol 2009;33(11):1713-9.
6. 6. Aram G, Rohwedder A, Nazeer T, Shoss R, Fisher A, Carlson JA. Varicella-Zoster-Virus folliculitis promoted clonal cutaneous lymphoid hyperplasia. Am J Dermatopathol 2005;27(5):411-7.
7. 7. Cerroni L, Borroni RG, Massone C, Chott A, Kerl H. Cutaneous B-cell pseudolymphoma at the site of vaccination. Am J Dermatopathol 2007;29(6):538-42.
8. 8. Gambichler T, Kreuter JA, Stücker M, Kobyletzki GV, Altmeyer P, Hoffmann K. Guess what! Cutaneous lymphoid hyperplasia. Eur J Dermatol 2000;10(8):635-6.

9. 9. Bouloc A, Delfau-Larue MH, Lenormand B, Meunier F, Wechsler J, Thomine E, et al. Polymerase chain reaction analysis of immunoglobulin gene rearrangement in cutaneous lymphoid hyperplasias. French Study Group for Cutaneous Lymphomas. Arch Dermatol 1999;135(2):168-72.