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Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri

Yıl 2021, Cilt: 10 Sayı: 2, 24 - 35, 08.10.2021

Öz

Son yıllarda; probiyotikler ve prebiyotiklerin sağlık üzerine faydaları hakkındaki araştırmalarda önemli bir artış olmuştur. Sindirim sistemindeki mikroflora insan ve hayvan sağlığı açısından çok önemli bir yere olup, günümüzde bu mikroflorayı patojenlere karşı korumak için prebiyotik ve probiyotik gibi katkı maddeleri kullanılmaktadır. Probiyotik; konakçı canlıda yararlı etkisi olan, bağırsak mikrobiyal dengesini geliştiren canlı mikroorganizmalar olarak ifade edilmektedir. Yapılan birçok çalışma probiyotiklerin bağışıklık sistemini uyarabildiğini, serum kolesterolünü azaltabildiğini, laktoz intoleransını azaltabildiğini, diyare vakalarını azaltabildiğini, enfeksiyonları kontrol ettiğini, antibiyotik görevi gördüğünü, tümörleri baskıladığını ve kolon/mesane kanserine karşı koruma sağladığını göstermiştir. Probiyotikler bu etkileri ile insan beslenmesinin yanı sıra bağırsaktaki bakteri dengesini iyileştirmek için fonksiyonel katkı maddeleri olarak yemlere eklenmektedir. Prebiyotik; insan ve hayvan sağlığına yararlı yönde etki eden, bağırsakta fermente olan ve kolon bakterilerinin gelişimini sağlayan, sindirilemeyen karbonhidratlar olarak ifade edilmektedir. Prebiyotikler; bitkilerden ekstraksiyon, mikrobiyolojik veya enzimatik sentez, polisakkaritlerin enzimatik hidrolizi gibi üç farklı şekilde üretilebilmektedir. Bu derleme makalede; probiyotiklerin ve prebiyotiklerin tanımı, etki mekanizmaları, özellikleri, insan ve hayvan sağlığı için önemi ile ilgili konular ele alınmıştır.

Kaynakça

  • Akman, E., 2009. Bazı laktik asit bakterilerinin probiyotik özelliklerinin incelenmesi, Yüksek lisans tezi, İ.T.Ü. Fen Bilimleri Enstitüsü, İstanbul.
  • Anadon, A., Castellano, V., Martínez-Larrañaga, M.R., 2014. Regulation and guidelines of probiotics and prebiotics. In: Ötles S, editor. Probiotics and prebiotics in food, nutrition and health. Boca Raton, FL: CRC Press, LLC Taylor & Francis Group; 91–113.
  • Anonymous, 2006b. Feed and animal health. Animal Feed Science and Technology. 126, 173-174.
  • Antunovic, Z., Speranda, M., Liker, B., Seric, V., Steiner, Z., Domacinovic, M., 2005. Influence of feding the probiotic pioneer to growing lambs on performances and blood composition. Acta Veterinaria, 55(4), 287-300.
  • Ayad, M.A., Benallou, B., Saim, M.S., Smadi, M.A., Meziane T., 2013. Impact of feeding yeast culture on milk yield, milk components, and blood components in Algerian dairy herds. Journal of Veterinary Science and Technology. 4(2), 1-5.
  • Bach, A., 2006. Meal frequency important in acidosis prevention. Feed Mix. 14 (4),13-15.
  • Baysal, A., 2010. Genel Beslenme 13. Baskı, Hatiboğlu Yayınevi, Ankara.
  • Borchers, A.T., Selmi, C., Meyers, F.J., Keen, C.L., Gershwin, M.E., 2009. Probiotics and immunity. J. Gastroenterol. 44, 26-46.
  • Brandao, R.L., Castro, I.M., Bambirra, E.A., Amaral, S.C., Fietto, L.G., Tropia, M.J.M. 1998. Intracellular signal triggered by cholera toxin in Saccharomyces boulardii and Saccharomyces cerevisiae. Applied and Environmental Microbiology. 64, 564–568.
  • Chandan, R., 1997. Dairy-based ingredients. American Association of Cereal Chemists, St. Paul, M.N., 96-99.
  • Chateau, N., Castellanos, I., Deschamps, A.M., 1993. Distribution of pathogen inhibition in the Lactobacillus isolates of commercial probiotic consortium. Journal of Applied Bacteriology. 74, 36-40.
  • Chen, Y.C., Chen, T.C., 2003. Effect of adding chicory fructans in feed on broiler growth performance, serum cholesterol and intestinal lenght. International Journal of Poultry Science. 2(3), 214-219.
  • Coşkun, H., 2006. Pro-, Pre- ve Sinbiyotikler. Çocuk Sağlığı ve Hastalıkları Dergisi. 49, 128-148.
  • Crittenden, R.G., Playne, M.J., 1996. Production, properties and applications of food-grade oligosaccharides. Trends in Food Science & Technology. 7, 353-360.
  • Crittenden, R., Playne, M.J., 2009. Prebiotics. In Handbook of Probiotics and Prebiotics; Lee, Y.K., Salminen, S., Eds.; John Wiley & Sons Inc.: Hoboken, N.J., USA, 535–561.
  • Çakırcalı, E., 1998. Hemşirelikte Temel İlke ve Uygulamalar, II. Baskı, Ege Üniversitesi Matbaası, İzmir, 149-154.
  • Dimer, C., Gibson, G.R., 1998. An overview of probiotics, prebiotics and synbiotics in the functional food concept: perspectives and future strategies. International Dairy Journal. 8, 473-479.
  • Famularo, C., Moretti, S., Marcellini, De, Simone, C., 1997. Stimulation of immunity by probiotics. In: Fuller, R., editor. Probiotics 2 applications and practical aspects. London, England. 133-61.
  • Gibson, G.R., Roberfroıd, M.B., 2008. Handbook of Prebiotics. Boca Raton, Florida: CRC Press.
  • Gibson, G. R., Scott, K. P., Rastall, R. A., Tuohy, K. M., Hotchkiss, A., Dubert-Ferrandon, A., ... & Buddington, R., 2011. Dietary prebiotics: current status and new definition. Food Science & Technology Bulletin Functional Foods. 7(1), 1-19.
  • Görgülü M., Öngel E., Yurtseven S., Kutlu HR., Siuta A., 2001. Effects of probiotic on growing performance and health of calves. Çukurova Üniversitesi Ziraat Fakültesi Dergisi, 16, 73-78.
  • Guillot, J.F., 2003. Probiotic feed additives. Journal of Veterinary Pharmacology and Therapeutics. 26, 52-55.
  • Gulewicz, P., Ciesiolka, D., Frias, J, Vidal-Valverde C., Frejnagel, S., Trojanowska, K., Gulewicz, K., 2003. Simple method of isolation and purification of α-galactosides from legumes. Journal of Agricultural and Food Chemistry. 48, 3120–3123.
  • Guo, J. R., Dong, X. F., Liu, S., & Tong, J. M. 2017. Effects of long-term Bacillus subtilis CGMCC 1.921 supplementation on performance, egg quality, and fecal and cecal microbiota of laying hens. Poultry Science. 96(5), 1280-1289.
  • Güler K., Başaran K., 2003. Yem katkı maddesi olarak kullanılan biyoteknolojik ürünler. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi. 43(1), 61-74.
  • Hasan, Rüştü, Kutlu., Nihat, Özen., 2009. Hayvan Beslemede Son Gelişmeler. VI. Ulusal Zootekni Bilim Kongresi, Atatürk Üniversitesi, Erzurum.
  • Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D. J., Pot, B., ... & Sanders, M. E. 2014. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews Gastroenterology & Hepatology, 11(8), 506-514.
  • Hillal, H., El-Sayaad, G., Abdella, M., 2011. Effect of growth promoters (probiotics) supplementation on performance, rumen activity and some blood constituents in growing lambs. Archiv Tierzucht. 54(6), 607-617.
  • Holzapfel, W.H., Schillinger, U., 2002. İntroduction top re-and probiotics. Food Research International. 35, 109-116.
  • Iemoli, E., Trabattoni, D., Parisotto, S., Borgonovo, L., Toscano, M., Rizzardini, G., ... & Drago, L. 2012. Probiotics reduce gut microbial translocation and improve adult atopic dermatitis. Journal of clinical gastroenterology, 46, 33-40.
  • Iji, P.A., Tivey, D.R., 1999. The use of oligosaccharides in broiler diets. Proceedings of the 12th Europen Symposium on Poultry Nutrition. 129, 1402-1406. World’s Poultry Sci. Assoc., Dutch Branch. Veldhoven, the Netherlands.
  • Isolauri, E., Moreau, M.C., Roberfroid, M., Rowland, I., 2001. Functional food science and gastrointestinal physiology and function. British Journal of Nutrition. 80 (1), 147.
  • Isolauri, E., Sutas, Y., Kankaanpaa, P., Arvilommi, H., Salminen, S., 2001. Probiotics: Effects on immunity. The American Journal of Clinical Nutrition. 73, 444–450.
  • Isolauri, E., 2003. Probiotics for infectious diarrhoea. Gut, 52(3), 436-437.
  • Ivanovic, S., Pisinov, B., Maslic-Strizak, D., Savic, B., Stojanovic, Z., 2012. Influence of probiotics on quality of chicken meat. African Journal of Agricultural Research, 7, 2191-2196.
  • Jacela, J. Y., DeRouchey, J. M., Tokach, M. D., Goodband, R. D., Nelssen, J. L., Renter, D. G., & Dritz, S. S., 2010. Feed additives for swine: Fact sheets–prebiotics and probiotics, and phytogenics. Journal of Swine Health and Production, 18(3), 132-136.
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  • Karademir, G. ve Karademir, B., 2003. Yem katkı maddesi olarak kullanılan biyoteknolojik ürünler. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi, 43, 61-74.
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Importance of Probiotics and Prebiotics in Animal Nutrition and Their Effects on Health

Yıl 2021, Cilt: 10 Sayı: 2, 24 - 35, 08.10.2021

Öz

There is a significant increase in research about the health benefits of probiotics and prebiotics, in recent years. The microflora of digestive system is very important both for human and animal health, and today, the food additives such as prebiotics and probiotics are used to protect this microflora against to pathogens. Probiotics are living microorganisms that have a beneficial effect on the host organism and improve the intestinal microbial balance. Many studies have shown that probiotics can stimulate the immune system, reduce serum cholesterol, reduce lactose intolerance, reduce cases of diarrhea, control infections, act as antibiotics, suppress tumors, and protect against colon / bladder cancer. Because of these effects, probiotics are added to human nutrition as well as animal feeds as functional additives to improve the bacterial balance in the intestine. Prebiotics are indigestible carbohydrates that have a beneficial effect on human and animal health, ferment in the intestine and provide the growth of colon bacteria. Prebiotics can be produced in three different ways such as extraction from plants, microbiological way or enzymatic synthesis, enzymatic hydrolysis of polysaccharides. In this review article; definition of probiotics and prebiotics, their mechanism of action, their properties, their importance for human and animal health were all discussed.

Kaynakça

  • Akman, E., 2009. Bazı laktik asit bakterilerinin probiyotik özelliklerinin incelenmesi, Yüksek lisans tezi, İ.T.Ü. Fen Bilimleri Enstitüsü, İstanbul.
  • Anadon, A., Castellano, V., Martínez-Larrañaga, M.R., 2014. Regulation and guidelines of probiotics and prebiotics. In: Ötles S, editor. Probiotics and prebiotics in food, nutrition and health. Boca Raton, FL: CRC Press, LLC Taylor & Francis Group; 91–113.
  • Anonymous, 2006b. Feed and animal health. Animal Feed Science and Technology. 126, 173-174.
  • Antunovic, Z., Speranda, M., Liker, B., Seric, V., Steiner, Z., Domacinovic, M., 2005. Influence of feding the probiotic pioneer to growing lambs on performances and blood composition. Acta Veterinaria, 55(4), 287-300.
  • Ayad, M.A., Benallou, B., Saim, M.S., Smadi, M.A., Meziane T., 2013. Impact of feeding yeast culture on milk yield, milk components, and blood components in Algerian dairy herds. Journal of Veterinary Science and Technology. 4(2), 1-5.
  • Bach, A., 2006. Meal frequency important in acidosis prevention. Feed Mix. 14 (4),13-15.
  • Baysal, A., 2010. Genel Beslenme 13. Baskı, Hatiboğlu Yayınevi, Ankara.
  • Borchers, A.T., Selmi, C., Meyers, F.J., Keen, C.L., Gershwin, M.E., 2009. Probiotics and immunity. J. Gastroenterol. 44, 26-46.
  • Brandao, R.L., Castro, I.M., Bambirra, E.A., Amaral, S.C., Fietto, L.G., Tropia, M.J.M. 1998. Intracellular signal triggered by cholera toxin in Saccharomyces boulardii and Saccharomyces cerevisiae. Applied and Environmental Microbiology. 64, 564–568.
  • Chandan, R., 1997. Dairy-based ingredients. American Association of Cereal Chemists, St. Paul, M.N., 96-99.
  • Chateau, N., Castellanos, I., Deschamps, A.M., 1993. Distribution of pathogen inhibition in the Lactobacillus isolates of commercial probiotic consortium. Journal of Applied Bacteriology. 74, 36-40.
  • Chen, Y.C., Chen, T.C., 2003. Effect of adding chicory fructans in feed on broiler growth performance, serum cholesterol and intestinal lenght. International Journal of Poultry Science. 2(3), 214-219.
  • Coşkun, H., 2006. Pro-, Pre- ve Sinbiyotikler. Çocuk Sağlığı ve Hastalıkları Dergisi. 49, 128-148.
  • Crittenden, R.G., Playne, M.J., 1996. Production, properties and applications of food-grade oligosaccharides. Trends in Food Science & Technology. 7, 353-360.
  • Crittenden, R., Playne, M.J., 2009. Prebiotics. In Handbook of Probiotics and Prebiotics; Lee, Y.K., Salminen, S., Eds.; John Wiley & Sons Inc.: Hoboken, N.J., USA, 535–561.
  • Çakırcalı, E., 1998. Hemşirelikte Temel İlke ve Uygulamalar, II. Baskı, Ege Üniversitesi Matbaası, İzmir, 149-154.
  • Dimer, C., Gibson, G.R., 1998. An overview of probiotics, prebiotics and synbiotics in the functional food concept: perspectives and future strategies. International Dairy Journal. 8, 473-479.
  • Famularo, C., Moretti, S., Marcellini, De, Simone, C., 1997. Stimulation of immunity by probiotics. In: Fuller, R., editor. Probiotics 2 applications and practical aspects. London, England. 133-61.
  • Gibson, G.R., Roberfroıd, M.B., 2008. Handbook of Prebiotics. Boca Raton, Florida: CRC Press.
  • Gibson, G. R., Scott, K. P., Rastall, R. A., Tuohy, K. M., Hotchkiss, A., Dubert-Ferrandon, A., ... & Buddington, R., 2011. Dietary prebiotics: current status and new definition. Food Science & Technology Bulletin Functional Foods. 7(1), 1-19.
  • Görgülü M., Öngel E., Yurtseven S., Kutlu HR., Siuta A., 2001. Effects of probiotic on growing performance and health of calves. Çukurova Üniversitesi Ziraat Fakültesi Dergisi, 16, 73-78.
  • Guillot, J.F., 2003. Probiotic feed additives. Journal of Veterinary Pharmacology and Therapeutics. 26, 52-55.
  • Gulewicz, P., Ciesiolka, D., Frias, J, Vidal-Valverde C., Frejnagel, S., Trojanowska, K., Gulewicz, K., 2003. Simple method of isolation and purification of α-galactosides from legumes. Journal of Agricultural and Food Chemistry. 48, 3120–3123.
  • Guo, J. R., Dong, X. F., Liu, S., & Tong, J. M. 2017. Effects of long-term Bacillus subtilis CGMCC 1.921 supplementation on performance, egg quality, and fecal and cecal microbiota of laying hens. Poultry Science. 96(5), 1280-1289.
  • Güler K., Başaran K., 2003. Yem katkı maddesi olarak kullanılan biyoteknolojik ürünler. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi. 43(1), 61-74.
  • Hasan, Rüştü, Kutlu., Nihat, Özen., 2009. Hayvan Beslemede Son Gelişmeler. VI. Ulusal Zootekni Bilim Kongresi, Atatürk Üniversitesi, Erzurum.
  • Hill, C., Guarner, F., Reid, G., Gibson, G. R., Merenstein, D. J., Pot, B., ... & Sanders, M. E. 2014. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews Gastroenterology & Hepatology, 11(8), 506-514.
  • Hillal, H., El-Sayaad, G., Abdella, M., 2011. Effect of growth promoters (probiotics) supplementation on performance, rumen activity and some blood constituents in growing lambs. Archiv Tierzucht. 54(6), 607-617.
  • Holzapfel, W.H., Schillinger, U., 2002. İntroduction top re-and probiotics. Food Research International. 35, 109-116.
  • Iemoli, E., Trabattoni, D., Parisotto, S., Borgonovo, L., Toscano, M., Rizzardini, G., ... & Drago, L. 2012. Probiotics reduce gut microbial translocation and improve adult atopic dermatitis. Journal of clinical gastroenterology, 46, 33-40.
  • Iji, P.A., Tivey, D.R., 1999. The use of oligosaccharides in broiler diets. Proceedings of the 12th Europen Symposium on Poultry Nutrition. 129, 1402-1406. World’s Poultry Sci. Assoc., Dutch Branch. Veldhoven, the Netherlands.
  • Isolauri, E., Moreau, M.C., Roberfroid, M., Rowland, I., 2001. Functional food science and gastrointestinal physiology and function. British Journal of Nutrition. 80 (1), 147.
  • Isolauri, E., Sutas, Y., Kankaanpaa, P., Arvilommi, H., Salminen, S., 2001. Probiotics: Effects on immunity. The American Journal of Clinical Nutrition. 73, 444–450.
  • Isolauri, E., 2003. Probiotics for infectious diarrhoea. Gut, 52(3), 436-437.
  • Ivanovic, S., Pisinov, B., Maslic-Strizak, D., Savic, B., Stojanovic, Z., 2012. Influence of probiotics on quality of chicken meat. African Journal of Agricultural Research, 7, 2191-2196.
  • Jacela, J. Y., DeRouchey, J. M., Tokach, M. D., Goodband, R. D., Nelssen, J. L., Renter, D. G., & Dritz, S. S., 2010. Feed additives for swine: Fact sheets–prebiotics and probiotics, and phytogenics. Journal of Swine Health and Production, 18(3), 132-136.
  • Kamada, H., Nonaka, I., Ueda, Y., Murai, M., 2006. Seleinum increase immunoglobulin G absorption by the intestinal pinocytosis of newborn calves. Book of Abstracts of the 57th Annual Meeting of the European Association for Animal Production. 120, 17-20 Sept. 2006, Antalya-Turkey.
  • Karademir, G. ve Karademir, B., 2003. Yem katkı maddesi olarak kullanılan biyoteknolojik ürünler. Lalahan Hayvancılık Araştırma Enstitüsü Dergisi, 43, 61-74.
  • Kavas, N., 2011. Fonksiyonel Keçi Peyniri Üretiminde Sinbiyotik Mikrokapsüllerin Kullanımı ve Canlılıklarının İncelenmesi. Doktora Tezi. Ege Üniversitesi Fen Bilimleri Enstitüsü
  • Kim, H. W., Miller, D. K., Yan, F., Wang, W., Cheng, H. W., Yuan, H., Kim, B., 2017. Probiotic supplementation and fast freezing to improve quality attributes and oxidation stability of frozen chicken breast muscle. LWT- Food Science and Technology, 75, 34-41.
  • Krause, K. M., Oetzel, G. R., 2006. Understanding and preventing subacute ruminal acidosis in dairy herds: A review. Animal feed science and technology, 126(3-4), 215-236.
  • Kum, C., Sekkin, S. 2012. Alternative approaches to antibiotics. Turkiye Klinikleri Journal of Veterinary Sciences Journal, 3(3), 84-116.
  • Kutlu, H.R. ve Çelik, L., 2005. Yemler Bilgisi ve Yem Teknolojisi. Ç.Ü. Ziraat Fak. Genel Yayın No:266, Ders Kitapları Yayın No:A-86, Adana.
  • Lubbadeh, W., Haddadin, M.S.Y., Al-Tamimi, M.A., Robinson, R.K., 1999. Effect on the cholesterol content of fresh lamb of supplementing the feed of Awasi ewes and lambs with Lactobacillus acidophilus. Meat Science, 52, 381- 385.
  • Manning, T. S., Gibson, G. R. 2004. Prebiotics. Best practice & research clinical gastroenterology, 18(2), 287-298.
  • Mansoor, S. (2015). Nutrition education curriculum for training physicians in medical colleges of Pakistan. Pakistan Armed Forces Medical Journal, 65(3), 382-385.
  • Markowiak, P., & Śliżewska, K., 2017. Effects of probiotics, prebiotics, and synbiotics on human health. Nutrients, 9(9), 1021. Marteau, P., Seksik, P., Jian, R., 2002. Probiotics and intestinal health effects: a clinical perspective. British Journal of Nutrition. 88 (1), 51.
  • McArdle, W., Katch, F.I., Katch L.V., 2007. Exercise Physiology, Energy, Nutrition and Human Performance, 6th Edition, Lippincott Williams & Wilkins.
  • McFadden, J.W., Block, S.S., Drackley, J.K., 2008. Assessment of blended sorbitol and mannitol as a glucogenic precursor for periparturient dairy cows. Animal Feed Science and Technology, 140, 233-240.
  • Mussatto, S.I., Mancilha, I.M., 2007. Non-digestible oligosaccarides. Carbohidrate Polymers, 68, 587-597.
  • Niewold, T.A., 2007. The Nonantibiotic anti-inflammatory effect of antimicrobial growth prometers, the real mode of action? A hypotesis. Poult. Sci. 86, 605-609.
  • Nurmi, E., Schneitz, C.E., Makela, P.H., 1983. Process for the production of a bacterial preparation. Canadian Patent no. 1151066.
  • O’Bryan, C. A., Pak, D., Crandall, P. G., Lee, S. O., Ricke, S. C., 2013. The role of prebiotics and probiotics in human health. Journal of Probiotics and Health, 1(2), 1-8.
  • Parracho, H., McCartney A.L., Gibson, G.R., 2007. Probiotics and prebiotics in infant nutrition. Proceedings of the Nutrition Society, 66, 405-411.
  • Pyne, D.B., West, N.P., Cripps, A.W., 2012. Probiotics and immune response to exercise. European Journal of Sport Science. 7(1), 51-59.
  • Roodposhti, P., M., Dabiri, N. 2012. Effects of probiotic and prebiotic on average daily gain, fecal shedding of Escherichia coli, and immune system status in newborn female calves. Asian-Australasian Journal of Animal Sciences, 25(9), 1255 – 1261.
  • Salminen, S., Bouley, C., Boutron-Ruault, M.C., Cummings, J.H., Franck, A., Gibson, G.R., 1998. Functional food science and gastrointestinal physiology and function, British Journal of Nutrition. doi: 10.1079/bjn19980108. Samona, A., Robinson, R.K., 1994. Effect of yogurt cultures on the survival of Bifidobacteria in fermented milks. International Journal of Dairy Technology, 47, 58-60.
  • Scheinbach, S., 1998. Probiotics: functionality and commercial status. Biotechnology Advances, 16, 581-608.
  • Seo, Y. S., Lim, J. Y., Choi, B. S., Kim, H., Goo, E., Lee, B., ... & Hwang, I. 2011. Complete genome sequence of Burkholderia gladioli BSR3. Journal of bacteriology.
  • Sharma, S., Agarwal, N., Verma, P. 2012. Miraculous health benefits of prebiotics. International Journal of Pharmaceutical Sciences and Research, 3(6), 1544.
  • Shin, H.S., Lee, H., Pestka, J.J., Ustunol, Z., 2000. Growth and viability of commercial Bifidobacterium spp. in skim milk containing oligosaccharides and inulin. Journal of Food Science, 65, 884-887.
  • Sivieri, K., Morales, M.L.V., Saad, S.M.I., Adorno, M.A.T., Sakamoto, I.K., Rossi, E.A., 2014. Prebiotic effect of fructooligosaccharide in the simulator of the human intestinal microbial ecosystem (SHIME (R) Model). Journal of Medicinal Food,17, 894–901.
  • Slizewska, K., Nowak, A., Barczynska, R., Libudzisz, Z. 2013. Prebiotyki-definicja, właściwości i zastosowanie w przemyśle. Żywność Nauka Technologia Jakość, 20(1).
  • Sulabo, R.C., Jacela, J.Y., DeRouchey, J.M., Tokach, M.D., Neher, F., Goodband, R.D., Dritz, S.S., Nelssen, J.L., 2007. Effects of phytobiotics (BIOMIN® P.E.P.) on nursery pig performance. Kansas Agricultural Experiment Station Research Reports. 985, 94-98.
  • Takahashi, T., Nakagawa, E., Nara, T., Yajima, T., Kuwata, T., 1998. Effects of orally ingested Bifidobacterium longum on the mucosal IgA response of mice to dietary antigens. Bioscience, Biotechnology, and Biochemistry. 62, 10–5.
  • Tunç, M.A., 2007. Humatların koyunlarda rumen parametreleri ve bazı kan değerleri üzerine etkisi. Yüksek Lisans Tezi, Atatürk Üniv. Hayvan Besleme ve Beslenme Hastalıkları A.D., Erzurum, 9.
  • Van den Abbeele, P., Venema, K., Van de Wiele, T., Verstraete, W., Possemiers, S., 2013. Different human gut models reveal the distinct fermentation patterns of arabinoxylan versus inulin. Journal of agricultural and food chemistry, 61(41), 9819-9827.
  • Vandenbergh, P.A., 1993. Lactic acid bacteria, their metabolic products and interference with microbial growth. FEMS Microbiology Reviews,12, 221-238.
  • Verstegena, M.W.A., Williamsa, B.A., 2002. Animal Biotechnology, ISSN: 1532-2378, Alternatives to the use of antibiotics as growth promoters for monogastric animals, Department of Animal Sciences, Animal Nutrition Group, Wageningen University 13(1), 113-127.
  • Vuyst, L., Falony, G., Leroy, F., 2008. Probiotics in fermented sausages. Meat Science, 80, 75-78.
  • Wang, Y., 2009. Prebiotics: Present and future in food science and technology. Food Research International, 42, 8-12.
  • Willing, B.P., Malik, G., Van, Kessel, A.G., 2012. Nutrition and gut health in swine. In: Chiba L.I., editor. Sustainable swine nutrition. Chichester: Wiley. 197–213.
  • Yeşilbağ, D., Eren, M., 2008. Effect of dietary boric acid supplementation on performance, eggshell quality and some parameters in aged laying hens. Turkish Journal of Veterinary and Animal Sciences. 32 (2), 113-117.
  • Zhou, X., Wang, Y., Gu, Q., Li, W. 2010. Effect of dietary probiotic, Bacillus coagulans, on growth performance, chemical composition, and meat quality of Guangxi Yellow chicken. Poultry science, 89(3), 588-593.
  • Ziggers, D. 2006. Feed additives, what they were and what they have become. Feed Technology, 10(1), 16-19.
  • Zimmer, C.J., Gibson, G.R., 1998. An overview of probiotics, prebiotics and synbiotics in the functional food concept: perspectives and future strategies. International Dairy Journal 8, 473-479.
Toplam 76 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Mühendislik
Bölüm Derleme Makaleler
Yazarlar

Ceren Atılgan Bu kişi benim 0000-0001-8907-234X

Şeniz Karabıyıklı Çiçek 0000-0001-9287-9400

Erken Görünüm Tarihi 2 Eylül 2021
Yayımlanma Tarihi 8 Ekim 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 10 Sayı: 2

Kaynak Göster

APA Atılgan, C., & Karabıyıklı Çiçek, Ş. (2021). Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri. Gaziosmanpaşa Bilimsel Araştırma Dergisi, 10(2), 24-35.
AMA Atılgan C, Karabıyıklı Çiçek Ş. Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri. GBAD. Ekim 2021;10(2):24-35.
Chicago Atılgan, Ceren, ve Şeniz Karabıyıklı Çiçek. “Hayvanların Beslenmesinde Probiyotik Ve Prebiyotiklerin Önemi Ve Sağlık Üzerine Etkileri”. Gaziosmanpaşa Bilimsel Araştırma Dergisi 10, sy. 2 (Ekim 2021): 24-35.
EndNote Atılgan C, Karabıyıklı Çiçek Ş (01 Ekim 2021) Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri. Gaziosmanpaşa Bilimsel Araştırma Dergisi 10 2 24–35.
IEEE C. Atılgan ve Ş. Karabıyıklı Çiçek, “Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri”, GBAD, c. 10, sy. 2, ss. 24–35, 2021.
ISNAD Atılgan, Ceren - Karabıyıklı Çiçek, Şeniz. “Hayvanların Beslenmesinde Probiyotik Ve Prebiyotiklerin Önemi Ve Sağlık Üzerine Etkileri”. Gaziosmanpaşa Bilimsel Araştırma Dergisi 10/2 (Ekim 2021), 24-35.
JAMA Atılgan C, Karabıyıklı Çiçek Ş. Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri. GBAD. 2021;10:24–35.
MLA Atılgan, Ceren ve Şeniz Karabıyıklı Çiçek. “Hayvanların Beslenmesinde Probiyotik Ve Prebiyotiklerin Önemi Ve Sağlık Üzerine Etkileri”. Gaziosmanpaşa Bilimsel Araştırma Dergisi, c. 10, sy. 2, 2021, ss. 24-35.
Vancouver Atılgan C, Karabıyıklı Çiçek Ş. Hayvanların Beslenmesinde Probiyotik ve Prebiyotiklerin Önemi ve Sağlık Üzerine Etkileri. GBAD. 2021;10(2):24-35.