Pediatrik Beyin Tümörlerinde Gamma Knife

Öz

Pediatrik çağ beyin tümörleri tüm çocuk popülasyonu içinde lösemilerden sonra en sık görülen ikinci tümör tipleridir. Bu tümörlerin yönetimi erişkin çağ tümör yönetiminden birçok farklılıklar içermektedir. Kendilerine has özellikleri nedeni ile bu çağdaki beyin tümörlerinin yönetilmesi özelleşmiş ekiplerden oluşan multidisipliner yaklaşımları gerekli kılmaktadır. Bu derlemede genellikle erişkin çağ tümörleri için kullanılan Gamma Knife radyocerrahisinin çocukluk çağındaki kullanım alanları gözden geçirilmiştir.

Anahtar Kelimeler

• Gamma knife
• pediatrik beyin tümörleri
• radyocerrahi

Gamma Knife in Pediatric Brain Tumors

Öz

Pediatric brain tumors are the second most common tumor type after leukemia in the entire pediatric population. Management of these tumors has many differences from adult tumor management. Due to their unique characteristics, the management of brain tumors in this age requires multidisciplinary approaches consisting of specialized teams. In this review, the uses of Gamma Knife radiosurgery - which is generally used for adult tumors - in childhood are reviewed

Anahtar Kelimeler

• Gamma knife
• pediatric brain tumors
• radiosurgery

Kaynakça

1. Wells EM, Packer RJ. Pediatric brain tumors. Continuum (Minneap Minn) 2015; 21: 373-96.
2. Fleming AJ, Chi SN. Brain tumors in children. Curr Probl Pediatr Adolesc Health Care 2012; 42: 80-103.
3. Robertson PL. Advances in treatment of pediatric brain tumors. NeuroRx 2006; 3: 276-91.
4. Peker S. Radyocerrahi. In: Aksoy K (Ed.) Temel Nöroşirürji. Ankara: Türk Nöroşirürji Derneği Yayınları 2005: 836-43.
5. Regis J, Tamura M, Guillot C, Yomo S, Muraciolle X, Nagaje M et al. Radiosurgery with the world's first fully robotized Leksell Gamma Knife PerfeXion in clinical use: a 200-patient prospective, randomized, controlled compari- son with the Gamma Knife 4C. Neurosurgery 2009; 64: 346-55; discussion 55-6.
6. Hodgson DC, Goumnerova LC, Loeffler JS, Dutton S, Black PM, Alexander E, 3rd et al. Radiosurgery in the management of pediatric brain tumors. Int J Radiat Oncol Biol Phys 2001; 50: 929-35.
7. Raco A, Raimondi AJ, D'Alonzo A, Esposito V, Valentino V. Radiosurgery in the management of pediatric brain tumors. Childs Nerv Syst 2000; 16: 287-95.
8. Suh JH, Barnett GH. Stereotactic radiosurgery for brain tumors in pediatric patients. Technol Cancer Res Treat 2003; 2: 141-6.

9. King D, Connolly D, Zaki H, Lee V, Yeomanson D. Successful treatment of metastatic re- lapse of medulloblastoma in childhood with single session stereotactic radiosurgery: a report of 3 cases. J Pediatr Hematol Oncol 2014; 36: 301-4.
10. Patrice SJ, Tarbell NJ, Goumnerova LC, Shrieve DC, Black PM, Loeffler JS. Results of radiosurgery in the management of recurrent and residual medulloblastoma. Pediatr Neurosurg 1995; 22: 197-203.
11. Kano H, Niranjan A, Kondziolka D, Flickinger JC, Lunsford LD. Outcome predictors for intracranial ependymoma radiosurgery. Neuro- surgery 2009; 64: 279-87; discussion 87-8.
12. Stauder MC, Ni Laack N, Ahmed KA, Link MJ, Schomberg PJ, Pollock BE. Stereotactic radiosurgery for patients with recurrent intracranial ependymomas. J Neurooncol 2012; 108: 507-12.
13. Saleem MA, Hashim AS, Rashid A, Ali M. Role of gamma knife radiosurgery in multi- modality management of craniopharyngioma. Acta Neurochir Suppl 2013; 116: 55-60.
14. Park YS, Chang JH, Park YG, Kim DS. Recurrence rates after neuroendoscopic fenes- tration and Gamma Knife surgery in comparison with subtotal resection and Gamma Knife surgery for the treatment of cystic craniopharyngiomas. J Neurosurg 2011; 114: 1360-8.
15. Lekovic GP, Gonzalez LF, Shetter AG, Porter RW, Smith KA, Brachman D et al. Role of Gamma Knife surgery in the management of pineal region tumors. Neurosurg Focus 2007; 23: E12.
16. Yianni J, Rowe J, Khandanpour N, Nagy G, Hoggard N, Radatz M et al. Stereotactic ra- diosurgery for pineal tumours. Br J Neurosurg 2012; 26: 361-6.
17. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).