Transient hyperphosphatasemia in infants and children: a retrospective study of 43 cases

Öz

Objective: To describe the prevalence and clinical characteristics of elevated plasma ALP levels during a period of 3 years at our clinic. 

Material and Methods: We reviewed 533 children, retrospectively, to investigate the frequency, seasonal fluctuation, age distribution, and sex differences of the patients with the elevated ALP levels in younger than 5 years old children. 

Results: Twenty-four of the patients were girls (55.8%), and the mean age of the patients was 7.48±12.77 (1-60) months. The mean serum alkaline phosphatase (ALP) level was 1402.23 ± 440.4 U/L (1038-3135 U/L) and it was 3.33±1.04 (2.47-7.46) fold above upper range. Their ALP levels returned to normal in a mean period of 2.5 ± 1.1 (1 to 5) months. 

Conclusion: Early recognition of this benign entity, should help to avoid unnecessary tests.

Anahtar Kelimeler

• hyperphosphatasemia,infancy,children

Bebek Ve Çocuklarda Geçici Hiperfosfatazemi: 43 Olguluk Retrospektif Bir Çalişma

Öz

Amaç: Kliniğimizde 3 yıllık bir süre boyunca yüksek plazma ALP düzeylerinin prevalansını ve klinik özelliklerini tanımlamak.

Gereç ve Yöntem: artmış ALP düzeyleri olan 5 yaşın altındaki 533 çocuğunu geriye dönük olarak taradık ve frekans, mevsimsel dalgalanma, yaş dağılımı ve cinsiyet farklılıklarını araştırdık.

Bulgular: Yirmi dört hasta (% 55.8) kızdı ve yaş ortalaması 7.48 ± 12.77 (1-60) ay idi. Ortalama alkalin fosfataz (ALP) düzeyi 1402.23 ± 440.4 U / L (1038-3135 U / L) ve üst aralıktan 3.33 ± 1.04 (2.47-7.46) kat daha yüksekti. ALP seviyeleri, ortalama 2.5 ± 1.1 (1-5) aylık bir süre içinde normale döndü.

Sonuç: Bu iyi huylu antitenin erken tanınması, gereksiz testlerden kaçınmaya yardımcı ollabilir

Anahtar Kelimeler

• hiperfosfatazemi,bebeklik,çocuklar

Kaynakça

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