Fahr's Disease

Öz

Fahr's disease refers to sporadic or familial idiopathic basal ganglia, cerebral and cerebellar calcification. Patients may remain symptom-free but approximately two-thirds of the patients are symptomatic. Typical presentation starts in the 4th to 5th decades of life. Patients present with pyramidal, extrapyramidal, cerebellar, psychiatric and cognitive manifestations. Various diagnostic studies can be used to detect Fahr's disease and associated abnormalities. There is no specific treatment other than symptomatic support. In this review, clinical features and different types of presentations of Fahr's disease are discussed under the light of current literature.

Anahtar Kelimeler

• Fahr's disease, Clinical features, Presentation

Fahr Hastalığı

Öz

Fahr hastalığı, ailesel veya sporadik olabilen, idiopatik bazal ganglia, serebral ve serebellar kalsifikasyonla seyreden bir hastalıktır. Hastalar hiçbir belirti vermeyebilir, ancak hastaların yaklaşık olarak üçte ikisi semptomatiktir. Tipik prezentasyon dördüncü ve beşinci dekatlarda başlar. Hastalar piramidal, ekstrapiramidal, serebellar, psikiyatrik ve kognitif bulgularla başvurur. Bir çok tanısal çalışma hem Fahr hastalığının hem de ilişkili hastalıkların tanısını koymada kullanılabilir. Semptomatik tedavi dışında spesifik bir tedavisi yoktur. Bu derlemede Fahr hastalığının klinik özellikleri farklı prezentasyon şekilleri mevcut literatür eşliğinde incelenmiştir

Anahtar Kelimeler

• Fahr hastalığı, Klinik özellikler, Prezentasyon

Kaynakça

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