Magnetic Resonance Imaging Findings of Different Polymicrogyria Patterns

Öz

Aim: Polymicrogyria is a developmental cortical malformation, characterized by very small and prominent curling sulci that cause irregular vision at cortical surface and at the junction of cortex and white matter. In this study, magnetic resonance imaging findings of patients who have different polymicrogyria patterns were presented. Method: Eight women and 1 men, total 9 patients, whom were prediagnosed as motor mental retardation or different epilepsy types between 2008 and 2011 were enrolled in this study. All petients were radiologically imaged by 1,5 Tesla Magnetic Resonance Imaging device. Results: Bilateral perisylvian and bilateral parasagittal parieto-occipital polymicrogyria which were common types, detected in two patients. Rare types were detected in seven patients which were as follows; the left temporal common polymicrogyria, polymicrogyria from the left parasagittal, parietally, elongates to posterosuperior perisylvian cortical surfaces, left closed lip schizencephaly and in the neighborhood of perisylvian surface and schizencephaly line and with the parietooccipital polymicrogyria parietooccipital sulcus in the right and parasagittal occipital polymicrogyria, open-lipped on the left and closed lipped on the right schizencephaly and adjacent cortical surfaces with perisylvian polymicrogyria at the right, parasagittal paracingulate polymicrogyria, encephalocele sac at the anterior to the right frontal region with polymicrogyria elongates from adjacent cortical surfaces of forntal lob to insular cortex. Conclusion: As one of the most common types of developmental cortical malformations, polymicrogyria can be seen in patients who are presented with clinical findings, such as epilepsy, mental motor retardation and spasticity and polymicrogyria may present in very different types. MRI is an effective imaging technique in patients presenting with cortical developmental malformations such as polymicrogyria

Anahtar Kelimeler

• Magnetic resonance imaging, Polymicrogyria

Farklı Polimikrogiri Paternlerinin Manyetik Rezonans Görüntüleme Bulguları

Öz

Amaç: Polimikrogiri kortikal yüzey ve korteks ile beyaz cevher bileşkesinde irregüler görünüme yol açan aşırı küçük ve belirgin kıvrıntılı sığ sulkuslarla karakterize gelişimsel kortikal malformasyondur. Bu çalışmada farklı polimikrogiri paternlerine sahip hastaların manyetik rezonans görüntüleme bulguları sunulmaktadır. Materyal ve metod: Bu çalışmaya 2008-2011 yılları arasında mental motor retardasyon ve farklı tiplerde epilepsi ön tanıları olan, 2-58 yaş aralığında 8'i kadın, 1'i erkek toplam 9 hasta dahil edilmiştir. Tüm hastalara 1.5 Tesla manyetik rezonans cihazları ile beyin manyetik rezonans görüntüleme tetkiki uygulanmıştır. Bulgular: İki yaşındaki hastada sol temporal lobda yaygın polimikrogiri, 13 yaşındaki hastada sol parasagittal frontal bölgeden paryetalde posterosüperior perisilvian kortikal yüzeylere uzanan polimikrogiri formasyonu ve nodüler kortikal heterotopi odakları, 14 yaşındaki hastada sol kapalı dudaklı şizensefali ve perisilvian yüzeylerden şizensefali hattı komşuluğuna ve paryetooksipital kortikal yüzeylere uzanım gösteren polimikrogiri, sağda ise paryetooksipital sulkus ve parasagittal oksipital kortikal yüzeylerde polimikrogiri, 17 yaşındaki hastada sağ paryetooksipital sulkus ve sağ parasagittal oksipital kortikal yüzeylerde polimikrogiri, 18 yaşındaki hastada solda açık dudaklı, solda kapalı dudaklı şizensefali komşu kortikal yüzeylerde ve sağda parasilvian polimikrogiri ve parsiyel septum pellisidum agenezisi, 20 yaşındaki hastamızda bilateral perisilvian polimikrogiri, 24 yaşındaki hastada parsiyel kommüssüral agenezi ve parasagittal perisingülat kortikal polimikrogiri, 49 yaşındaki hastada bilateral parasagittal paryeto-oksipital polimikrogiri, 58 yaşındaki hastada sağ frontal bölge anteriorunda ensefalosel kesesi ve komşu frontal lobda kortikal yüzeylerden insular kortekse uzanan polimikrogiri formasyonu, hafif sağ hemimegalensefali ve ventriküler dismorfizm saptandı. Sonuç: Epilepsi, mental motor retardasyon, spastisite gibi klinik bulgularla gelen hastalarda polimikrogirinin atlanmaması için serebral parankimi manyetik rezonans görüntüleme tetkikiyle değerlendirme gerekir.

Anahtar Kelimeler

• Manyetik rezonans görüntüleme, Polimikrogiri

Kaynakça

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