Efficiency of antibiotic treatment of premature ejaculation in patients with type III prostatic inflammation

Öz

The most common male sexual disorder is premature ejaculation as it affects 30-40% of sexually active men. Various studies showed that the correlation of prostatic inflammation and chronic bacterial prostatitis with premature ejaculation is present in more than half of the sufferers. These studies also show that more than 85% of prostatic inflammation cases was shown to be caused by chronic prostatitis in the premature ejaculation patient group. Even though this relation is evident, the effect of antibiotic treatment of premature ejaculation in patients with chronic prostatitis has only recently being investigated extensively. In this study, 36 men suffering from secondary premature ejaculation who were included the study. These patients had no erectile dysfunction problems and were included in the study after they timed intravaginal ejaculatory latency in their last 3 intercourses to see that time was less than 2 minutes in each trial. To evaluate the prostatic inflammation, diagnosis was made by identifying 10 or more white blood cells per high power field in expressed prostatic secretions. 22 of 36 premature ejaculation patients in our study had more than 10 white blood cells in thier expressed prostatic secretions and were diagnosed to have prostatic inflammation. The other 14 patients were included in the study as the control group. Following one month antibiotic treatment 78% patients in the study group returned with the information that all 3 of their last intercourses ended with more than 2 minutes of intravaginal ejaculatory latency time while none of the control group reported similarly. No side effects were reported by any of the patients due to antibiotic usage. Our study shows that patients with PE that may benefit from month-long quinolone antibiotic therapy can be screened for by checking their expressed prostatic secretions under a microscope in the office. A more accurate definition of premature ejaculation, a scale for measuring the severity of PE, and a larger patient population would help generalize the findings of this study.

Anahtar Kelimeler

• Premature ejaculation, chronic prostatitis, antibiotic

Antibiyotik tedavisinin tip 3 kronik prostatitli hastalarda erken ejakülasyon üzerine olan etkinliği

Öz

Cinsel aktif erkeklerin %30-40’ını etkilediği için erken ejakülasyon erkeklerde en sık görülen cinsel işlev bozukluğudur. Çeşitli çalışmalar prostat inflamasyonu ve kronik bakteriyel prosttait ile erken ejakülasyon arasında ilişki olduğunu göstermiştir ki bu durum etkilene olguların %50’sinden fazla bulunmaktadır. Bu çalışmalar ayrıca prostatta inflamasyonu olan olguların %85’inden fazlasının erken ejakülasyon grubunda kronik prostatite bağlı bu bozukluğa yol açtığını göstermişlerdir. Bu ilişki belirgin olmasına rağmen kronik prosttaitli olgularda antibiyotik tedavisinin erken ejakülasyona olan etkileri yakın zamanlarda araştırılmaya başlanmıştır. Bu çalışmada sekonder erken ejakülasyon tanısı alan 36 erkek olgu değerlendirilmiştir. Olguların hiçbirinin erektil işlev bozukluğu yoktu. Bütün olgularda intravajinal ejakülatuvar latens zamanı 2 dakikanın altındaydı. Prostatik inflamasyon için her büyük büyütmede 10’un üzerinde lökosit olması anlamlı olarak kabul edildi. Toplam 36 olgunun 22’sinde prosttaik sekresyonda 10 ve üzerinde lökosit saptandı. Geri kalan 14 olgu kontrol grubu olarak kabul edildi. Bir aylık antibiyotik tedavisinin sonunda çalışma grubundaki olguların %78’inde son üç ilişkinin değerlendirilmesi ile intravajinal ejakülatuvar latens zamanının 2 dk ve üzerinde olduğu saptanırken diğer grupta benzer düzelme olmadığı görüldü. Hastaların hiçbirinde antibiyotik kullanımına bağlı yan etki bildirilmedi. Çalışmamız erken ejakülasyonu olup aylık uzun dönem antibiyotik tedavisinden fayda gören olguların prostatik inflamasyon için mikroskop altında değerlendirilmeleri gerektiğini ortaya koymaktadır.

Anahtar Kelimeler

• Cinsel işlev bozukluğu, erken ejakülasyon, kronik prostatit, antibiyotik

Kaynakça

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