Treatment of necrobiosis lipoidica with pimecrolimus in a child with diabetes mellitus

Öz

Necrobiosis lipoidica diabeticorum (NLD) is an idiopathic cutaneous granulomatous dermatitis. The disease is usually seen in people with diabetes mellitus. The treatment of NLD is quite difficult and takes a long time, particularly in ulcerated forms. In this case, a girl with 10 years of age is presented with a persistent plaque which had been present for 2.5 years on her left shin. Local treatment with pimecrolimus (Elidel 1.0% cream) twice daily for one month, in addition to glucose control provided a progressive improvement of the lesion. So, pimecrolimus may be used safely and effectively in the treatment of NLD.

Key words: child; diabetes mellitus; necrobiosis lipoidica; pimecrolimus 

Anahtar Kelimeler

• child; diabetes mellitus; necrobiosis lipoidica; pimecrolimus

Diyabetes mellituslu bir çocukta nekrobiyozis lipoidikanın pimekrolimus ile tedavisi

Öz

Nekrobiyozis lipoidika diyabetikorum (NLD), idiyopatik kutanöz granulamatöz bir dermatittir. Hastalık genellikle diyabetik popülasyonda görülür. NLD’nin tedavisi, özellikle ülsere formlarda, oldukça zordur ve uzun zaman alır. On yaşında kız çocuk, 2,5 yıldır sol bacağında olan inatçı bir plak ile başvurdu. Glikoz kontrolüne ek olarak bir ay boyunca günde iki kez lokal pimekrolimus (Elidel %1 krem) tedavisi ile lezyonda belirgin düzelme sağlandı. Sonuçta, pimekrolimus NLD tedavisinde güvenli ve etkili bir şekilde kullanılabilir.

 

Anahtar Kelimeler

• çocuk; diyabetes mellitus; nekrobiyozis lipoidika; pimekrolimus

Kaynakça

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