Neutrophil to Lymphocyte Ratio and Plateled to Lymphocyte Ratio in Patients with Pulmonary Embolism

Yıl 2018, Cilt: 8 Sayı: 2, 111 - 116, 17.05.2018

Serdar Savaş Gül Nurşah Başol

https://doi.org/10.16899/gopctd.410396

Öz

Objective: The aim of our study was to investigate clinical
importance of neutrophil to lymphocyte ratio (NLR) and plateled to lymphocyte
ratio (PLR) in patients with acute pulmonary embolism (PE).

Methods: 50 patients with a diagnosis of acute PE included
into the study between January 2016 and December 2017. NLR level was measured
by dividing neutrophil count to lymphocyte count. PLR level was measured by
dividing plateled count to lymphocyte count. Pre-treatment and post-treatment
groups of NLR and PLR values were compared.

Results: It has been NLR and PLR ratio have a significantly
higher value in admission and patients with pre-treatment groups were found
statistically significant variable to predict the treatment effects. Also,
correlation analysis showed a significant correlation between NLR and PLR.

Conclusion: NLR and PLR values
may be a useful biomarker for risk stratification and also prognosis for PE.

Anahtar Kelimeler

pulmonary embolism, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, ventilation-perfusion scintigraph

Pulmoner Emboli Hastalarında Nötrofil/Lenfosit Oranı ve Trombosit/Lenfosit Oranı

Öz

Amaç: Çalışmanın amacı akut pulmoner embolisi olan
hastalarda nötrofil/lenfosit oranının (NLR) ve plateled/lenfosit oranının (PLR)
klinik önemini araştırmaktır.

Yöntem: Ocak 2016 ile Aralık 2017 tarihleri ​​arasında akut pulmoner
emboli tanısı konan 50 hasta çalışmaya dahil edildi. NLR düzeyi, nötrofil
sayısının lenfosit sayısına bölünmesiyle ölçüldü. PLR düzeyi, plateled sayısının
lenfosit sayımına sayısına bölünmesiyle ölçüldü. NLR ve PLR ​​değerlerinin
tedavi öncesi ve tedavi sonrası grupları ile karşılaştırıldı.

Bulgular: Başvuruda NLR ve PLR ​​oranı anlamlı olarak yüksekti ve
tedavi öncesi grupların tedavi etkilerini tahmin etmek için istatistiksel
olarak anlamlı bir değişken olarak bulundu. Ayrıca, NLR ve PLR ​​arasında
anlamlı bir korelasyon saptandı.

Sonuç: NLR ve PLR
​​düzeyleri tedavi sonrası komorbidite için risk sınıflandırmasında yararlı ve
invazif olmayan bir biyobelirteç olabilir.

Anahtar Kelimeler

pulmoner emboli, nötrofil/lenfosit oranına, trombosit/lenfosit oranı, ventilasyon-perfüzyon sintigrafisi

Kaynakça

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