Rate Of Abnormal Coagulation Test Results in Patients with Congenital Heart Disease

Yıl 2011, Cilt: 1 Sayı: 1, 6 - 10, 01.03.2011

Mehmet Tayip Arslan Mustafa Ozcetin Ruhi Ozyurek Kaan Kavakli

Öz

Introduction: Coagluation abnormalities are expected in patients with congenital heart disease. We searched the rate of abnormal coagulation test in children with both cyanotic and non-cyanotic heart disease and investigated the clinical relevance of these abnormal tests. Material and Method: 49 children who have congenital heart disease and needed surgical intervention were prospectively enrolled to this study. Demographic data, primary diagnosis, bleeding complication during and after the intervention and prognosis of the patients were recorded. Platelet counts, prothrombin time, activated partial thromboplastine time and blood fibrinogen levels were measured prior to intervention. Results: 16 patients had prolonged PT, 13 patients had low fibrinogen level, 10 patients had prolonged aPTT and 5 patients had low platelet count. Conclusion: There was no increased complication risk in patients with abnormal test results, but caution must be taken during operation of these patients.Key words:

Anahtar Kelimeler

Coagulation test, Congenital Heart Disease, Disseminated Intravascular Coagulation, Fibrinolysis.

Konjenital Kalp Hastalığı Olan Hastalarda Anormal Koagülasyon Test Sonuçlarının Oranı

Öz

Giriş: Konjenital kalp hastalığı olan kişilerde pıhtılaşma bozuklukları beklenmektedir. Bu çalışmada siyanotik ve nonsiyanotik konjenital kalp hastalığı olan çocuklarda anormal koagulasyon test sıklığı ve bunun klinik önemi araştırılmıştır. Materyal ve Metod: Konjenital kalp hastalığı olan ve cerrahi müdahele ihtiyacı duyan 49 çocuk hasta prospektif olarak çalışmaya alınmıştır. Hastaların demografik bilgileri, primer tanıları, cerrahi müdahele ve sonrasında oluşan kanama bozukluğu ve hastaların prognozu kayıt edilmiştir.hastaların trombosit sayıları, protrombin zamanı, aktive parsiyel tromboplastin zamanı ile kan fibrinojen düzeyleri cerrahi müdahele öncesi saptanmıştır. Bulgular: 16 hastanın uzun PT, 13 hasta düşük fibrinojen düzeyi, 10 hastanın uzun aPTT ve 5 hastanın ise düşük trombosit sayısı olduğu saptanmıştır. Sonuç: Her ne kadar bozulmuş koagulasyon test sonuçları ile ilişkili artmuış bir komplikasyon saptanmamış olsa da bu hastalarda dikkatli olmak gerekmektedir.

Anahtar Kelimeler

Koagülasyon testleri, Konjenital kalp hastalığı, yaygın damariçi pıhtılaşma, fibrinoliz

Kaynakça

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