Postoperative Nausea and Vomiting in the Menstrual Cycling for Thyroidectomy Operations

Yıl 2015, Cilt: 5 Sayı: 2, 111 - 115, 09.03.2015

Asutay Orak Göktuğ Esra Uyar Türkyılmaz Handan Güleç Suna Akın Takmaz Hülya Başar

https://doi.org/10.16899/ctd.14080

Öz

Objective: Nausea-vomiting occurs approximately the rate of %63-84 after thyroidectomy operations. Women has the vomit incidens 5 times more than men. In some studies, it was shown that menstruel cyclus can impact post-operative vomit.

Methods: A hundered fifty women around the age of 18-49 has been involved in this study. First day of last menstrual cyclus was considered as starting day of next period. According to the operation day patients were divided tree groups in this period. First to 8th days are named as Follicular group (F) and 50 woman were involved. 9th to 16th days are named as Ovulatory group (O) and 50 woman were involved. 17th to last day of period are named as Luteal group (L) and 50 woman were involved. The same anesthetic procedures were performed to all patients. Aldrete Recovery Scala and Abromowitz Emesis Scores were recorded at actually extubation time, 5, 15, 30 th minutes, 1, 3, 6, 24th hours after extubation by the doctor who were not aware of this study.

Results: Working groups for age, sex, BMI, such as patient characteristics were similar in terms of study. Abramowitz Emesis scoring scale nausea and vomiting severity evaluated, a total of vomiting observed number of patients in group M (n = 47, 97%) Group O (n = 33, 66%) and Group L (n = 22, 44%) was greater than that

Conclusion: As a result, it was observed that nausea-womiting happens to the fertile women who had thyroidectomy in Group F more than the others.

Anahtar Kelimeler

Nausea, vomiting, thyroidectomy

Tiroidektomi Operasyonlarında Menstruel Siklusla Postoperatif Bulantı-Kusma İlişkisi

Öz

Amaç: Tiroidektomi operasyonlarından sonra yaklaşık %63-84 oranında bulantı-kusmaya rastlanır. Kadınlarda, bulantı-kusma insidansı erkeklerden 2-3 kat fazladır.

Yöntemler: On sekiz kırk dokuz yaş arası 150 kadın hasta çalışma kapsamına alındı. Hastaların son menstruel periyodunun ilk günü 1. gün sayılarak operasyona alındığı güne göre hastanın periyodu hesaplandıktan sonra, periyodunun 1-8. günleri arasında olan 50 hasta folliküler dönem (Grup F), 9-16. günler arasındaki 50 hasta ovulatuar dönem (Grup O), 17.gün ile menstruasyon arasındaki 50 hasta luteal dönem (Grup L), olarak gruplandırıldı. Tüm gruplara aynı standartta genel anestezi uygulandı. Ekstübasyon anında ve ekstubasyonun ardından 5, 15, 30. dakikalarda, 1.,3.,6. ve 24.saatlerde Aldrete derlenme ve Abromowitz emezis skorları çalışma gruplarından haberdar olmayan anestezi asistanı tarafından not edildi.

Bulgular: Her grupta toplam 50 hasta olacak şekilde toplam 150 hasta çalışma kapsamına alınmıştır. Çalışma grupları yaş, cinsiyet, VKİ gibi hasta özellikleri açısından benzerdiler.Abramowitz Emezis skorlamasına göre bulantı-kusma ciddiyeti değerlendirildiğinde, toplam kusma atağı gözlenen hasta sayısı Grup M’de (n=47, %97) Grup O (n=33, %66) ve Grup L’ye (n=22, %44) göre daha fazla bulunmuştur.

Sonuç: Sonuç olarak, tiroidektomi operasyonu geçiren fertil çağdaki kadınlarda menstrual siklusun folliküler döneminde daha fazla bulantı ile kusma atağı gözlendi.

 

Anahtar Kelimeler

Bulantı, kusma, tiroidektomi

Kaynakça

• Fujii Y, Tanaka H. Comparison of granisetron and ramosetron for the prevention of nausea and vomiting after thyroidectomy. Clin Ther 2002; 24(5):766 – 772.
• Alanoğlu Z, İltar GI, Eyigün H, Çanakçı N. Tiroidektomi cerrahisinde sevofluran, izofluran ve propofol ile total intravenöz anestezinin postoperatif bulantu ve kusma üzerine etkileri. T Klin Tıp Bilimleri 2003; 23:378-385.
• Watcha FM, White PF. Postoperative nausea and vomiting. Its etiology, treatment, and prevention. Anesthesiology 1992; 77: 162-84.
• Camu F, Lauwers MH, Verbessem D. Incidence and aetiology of postoperative nausea and vomiting.Eur J Anaesth 1992(suppl 6): 25-31.
• Kovac AL Prevention and treatment of postoperative nausea and vomiting. Drugs 2000 Feb;59(2):213-43
• Fujii Y,Tanaka H, Kobayashi N. Granisetron, Droperidol, and Metoclopramide for Preventing Postoperative Nausea and Vomiting After Thyroidectomy. The American Laryngological, Rhinological & Otalogical Society, Inc. 1999; 109(4): 664-667.
• Fujii Y, Toyooka H, Tanaka H. Prevention of postoperative nausea and vomiting in female patients during menstruation: comparison of droperidol, metoclopramide and granisetron. British J of Anaesthesia 1998; 80:248-249.
• Zelder J, Wells DG. Anaesthetic-related recovery room complications. Anaesthesia and Intensive Care 1987;15:168-74.
• Harmon D, O’Connor P, Glessa O, Gardiner J. Menstrual cycle irregularity and the incidence of nausea and vomiting after laparoscopy. Anaesthesia 2000; 55:1164-1167.
• Beattie S, Lindblad T, Buckley DN, Forrest JB. The incidence of postoperative nausea and vomiting in women undergoing laparoscopy is influenced by the day of menstrual cycle. Can J Anaesth 1991; 38 (3):298-302.
• Forrest JB, Cahalan MK, Rehder K et al. Multicenter study of general anesthesia. II. Results. Anesthesiology. 1990; 72: 262-8.
• Rita L, Goodarzi M, Seleny F. Effect of low dose droperidol on postoperative vomiting in children. Can Anaesth Soc J 1981; 28: 259-62.
• PommierRF, Woltering EA, Keenan EJ, Fletcher WS. The mechanism of hormone-sensitive breast cancer progression on antiestrogen therapy. Arch Surg 1987; 122: 1311-6.
• Benz C, Gandara D, Miller B et al. Chcmocndocrinc therapy with prolonged estrogen priming in advanced breast cancer: endocrine pharmacokinetics and toxicity. Cancer Treat Rep 1987; 71: 283-9.