Research Article

Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation

Volume: 38 Number: 2 June 1, 2025
EN

Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation

Abstract

Oral cancer holds a significant position among head and neck cancers and is encountered quite frequently. Oral cancer, which is the eleventh most common type of cancer worldwide, causes approximately 177,000 deaths and 350,000 new cases every year [1, 2]. The most commonly observed type of oral cancer is Oral Squamous Cell Carcinoma (OSCC) [6] which comprises about 90% of the cases [7]. The survival rate for OSCC is low due to the frequent late diagnosis [19]. This also underscores the importance of early diagnosis. Convolutional neural networks (CNN) are highly preferred for their high performance in early diagnosis. In this study, the early diagnosis of oral cancer has been investigated through the utilization of CNN. Additionally, two models are selected for each of the two different CNN architectures. Classification is carried out with varying hyperparameters on these four models, and the resulting classification accuracies were examined. Furthermore, the two architectures are compared in terms of their performance, highlighting the differences in accuracy and efficiency. The accuracy values for the DenseNet and ResNet architectures in this classification problem are investigated. Models were selected with varying layer depths within each architecture to understand how the number of layers affected classification accuracy. Furthermore, these processes are carried out with different optimizers and epoch numbers, aiming to explore the influence of optimizer choices and varying epoch numbers on classification accuracy. As a result of the study, the highest accuracy rate was measured as 97.01%, achieved using the DenseNet201 architecture with the SGD optimizer.

Keywords

Project Number

FYL-2024- 6104

References

  1. [1] Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R.L., Torre, L.A., Jemal, A. “Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries”, CA: a cancer journal for clinicians, 68(6): 394-424, (2018). DOI: 10.3322/caac.21492
  2. [2] Kalavrezos, N., Scully, C. “Mouth cancer for clinicians part 2: epidemiology”, Dental update, 42(4): 354-359, (2015). DOI: 10.12968/denu.2015.42.4.354
  3. [3] Sankaranarayanan, R., Ramadas, K., Amarasinghe, H., Subramanian, S., Johnson, N. “Oral cancer: prevention, early detection, and treatment”, Cancer: disease control priorities, third edition, 3: (2015). DOI: 10.1596/978-1-4648-0349-9_ch5
  4. [4] Sung, H., Ferlay, J., Siegel, R.L., Laversanne, M., Soerjomataram, I., Jemal, A., Bray, F. “Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries”, CA: a cancer journal for clinicians, 71(3): 209-249, (2021). DOI: 10.3322/caac.21660
  5. [5] World Health Organization. Oral Health. (2018). Available online: https://gco.iarc.fr/today/data/factsheets/cancers/1-Lip-oral-cavity-fact-sheet.pdf accessed on 11 March (2020). Access: https://gco.iarc.fr/today/en
  6. [6] Torres-Rosas, R., Torres-Gómez, N., Hernández-Juárez, J., Pérez-Cervera, Y., Hernández-Antonio, A., Argueta-Figueroa, L. “Reported epidemiology of cancer of the lip, oral cavity and oropharynx in Mexico”, Revista Medica del Instituto Mexicano del Seguro Social, 58(4): 494-507, (2020). DOI: 10.24875/rmimss.m20000075
  7. [7] Warnakulasuriya, S. “Global epidemiology of oral and oropharyngeal cancer”, Oral oncology, 45(4-5): 309-316, (2009). DOI: 10.1016/j.oraloncology.2008.06.002
  8. [8] Speight, P.M., Farthing, P.M. “The pathology of oral cancer”, British dental journal, 225(9): 841-847, (2018). DOI: 10.1038/sj.bdj.2018.926

Details

Primary Language

English

Subjects

Biostatistics, Biological Mathematics, Applied Mathematics (Other)

Journal Section

Research Article

Early Pub Date

April 28, 2025

Publication Date

June 1, 2025

Submission Date

May 8, 2024

Acceptance Date

January 4, 2025

Published in Issue

Year 2025 Volume: 38 Number: 2

APA
Süren, B., & Akar, M. (2025). Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation. Gazi University Journal of Science, 38(2), 1006-1019. https://doi.org/10.35378/gujs.1480477
AMA
1.Süren B, Akar M. Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation. Gazi University Journal of Science. 2025;38(2):1006-1019. doi:10.35378/gujs.1480477
Chicago
Süren, Betül, and Mutlu Akar. 2025. “Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation”. Gazi University Journal of Science 38 (2): 1006-19. https://doi.org/10.35378/gujs.1480477.
EndNote
Süren B, Akar M (June 1, 2025) Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation. Gazi University Journal of Science 38 2 1006–1019.
IEEE
[1]B. Süren and M. Akar, “Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation”, Gazi University Journal of Science, vol. 38, no. 2, pp. 1006–1019, June 2025, doi: 10.35378/gujs.1480477.
ISNAD
Süren, Betül - Akar, Mutlu. “Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation”. Gazi University Journal of Science 38/2 (June 1, 2025): 1006-1019. https://doi.org/10.35378/gujs.1480477.
JAMA
1.Süren B, Akar M. Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation. Gazi University Journal of Science. 2025;38:1006–1019.
MLA
Süren, Betül, and Mutlu Akar. “Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation”. Gazi University Journal of Science, vol. 38, no. 2, June 2025, pp. 1006-19, doi:10.35378/gujs.1480477.
Vancouver
1.Betül Süren, Mutlu Akar. Examination of ResNet and DenseNet Architectures in Early Diagnosis of Oral Cancer: An Evaluation. Gazi University Journal of Science. 2025 Jun. 1;38(2):1006-19. doi:10.35378/gujs.1480477