Research Article

Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine

Volume: 31 Number: 2 June 1, 2018
EN

Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine

Abstract

The purpose of the research was to evaluate the genotoxic and anti-genotoxic properties of Schiff bases and their Mn (III) complexes containing L-aspartic acid, and L-phenylalanine. The anti-genotoxic properties of four compounds in human lymphocytes cells were investigated by sister chromatid exchanges (SCEs) test system against aflatoxin B1 (AFB1). The results showed that compounds have strong anti-genotoxic properties.

 

Keywords

References

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  4. [4] Anar, M., Hasanoğlu Özkan, E., Öğütçü, H., Ağar, G., Şakıyan, I., Sarı, N., “Useful agents against aflatoxin B1–antibacterial azomethine and Mn(III) complexes involving L-Threonine, L-Serine, and L-Tyrosine”, Artificial Cells, Nanomedicine, and Biotechnology: An International Journal, 44: 853-858 (2016).
  5. [5] Şakıyan, I., Anar, M., Öğütçü, H., Ağar, G., Sarı, N., “Schiff bases attached L-glutamine and L-asparagine: First investigation on antimutagenic and antimicrobial analyses”, Artificial Cells, Nanomedicine, and Biotechnology: An International Journal, 42: 199-204 (2014).
  6. [6] Sakiyan, I., “Synthesis and characterization of four new manganese(III) complexes and amino acid (L-aspartic acid, L-asparagine, L-glutamic acid, L-glutamine) Schiff bases”, Transition Metal Chemistry, 32: 131–135 (2007).
  7. [7] Sakiyan, I., Gunduz, N., Gunduz, T., “Synthesis and characterization of manganese (III) complexes of Schiff bases derived from amino acids and 2-hydroxy-1-naphthaldehyde”, Synth React Inorg Met-Org Chem, 31: 1175–1187 (2001).
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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Elvan Hasanoğlu Özkan
Gazi University
Türkiye

Hamit Emre Kızıl This is me
BAYBURT ÜNİVERSİTESİ

İffet Şakıyan This is me
ANKARA ÜNİVERSİTESİ
Türkiye

Dilek Nartop
Düzce University
Türkiye

Nurşen Sarı
Gazi University
Türkiye

Güleray Ağar
ATATÜRK ÜNİVERSİTESİ
Türkiye

Publication Date

June 1, 2018

Submission Date

August 16, 2017

Acceptance Date

March 12, 2018

Published in Issue

Year 2018 Volume: 31 Number: 2

APA
Hasanoğlu Özkan, E., Kızıl, H. E., Şakıyan, İ., Nartop, D., Sarı, N., & Ağar, G. (2018). Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine. Gazi University Journal of Science, 31(2), 408-414. https://izlik.org/JA55BM43CC
AMA
1.Hasanoğlu Özkan E, Kızıl HE, Şakıyan İ, Nartop D, Sarı N, Ağar G. Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine. Gazi University Journal of Science. 2018;31(2):408-414. https://izlik.org/JA55BM43CC
Chicago
Hasanoğlu Özkan, Elvan, Hamit Emre Kızıl, İffet Şakıyan, Dilek Nartop, Nurşen Sarı, and Güleray Ağar. 2018. “Anti-Genotoxic Effects of Schiff Bases and Their Mn(III) Complexes Containing L-Aspartic Acid and L-Phenylalanine”. Gazi University Journal of Science 31 (2): 408-14. https://izlik.org/JA55BM43CC.
EndNote
Hasanoğlu Özkan E, Kızıl HE, Şakıyan İ, Nartop D, Sarı N, Ağar G (June 1, 2018) Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine. Gazi University Journal of Science 31 2 408–414.
IEEE
[1]E. Hasanoğlu Özkan, H. E. Kızıl, İ. Şakıyan, D. Nartop, N. Sarı, and G. Ağar, “Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine”, Gazi University Journal of Science, vol. 31, no. 2, pp. 408–414, June 2018, [Online]. Available: https://izlik.org/JA55BM43CC
ISNAD
Hasanoğlu Özkan, Elvan - Kızıl, Hamit Emre - Şakıyan, İffet - Nartop, Dilek - Sarı, Nurşen - Ağar, Güleray. “Anti-Genotoxic Effects of Schiff Bases and Their Mn(III) Complexes Containing L-Aspartic Acid and L-Phenylalanine”. Gazi University Journal of Science 31/2 (June 1, 2018): 408-414. https://izlik.org/JA55BM43CC.
JAMA
1.Hasanoğlu Özkan E, Kızıl HE, Şakıyan İ, Nartop D, Sarı N, Ağar G. Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine. Gazi University Journal of Science. 2018;31:408–414.
MLA
Hasanoğlu Özkan, Elvan, et al. “Anti-Genotoxic Effects of Schiff Bases and Their Mn(III) Complexes Containing L-Aspartic Acid and L-Phenylalanine”. Gazi University Journal of Science, vol. 31, no. 2, June 2018, pp. 408-14, https://izlik.org/JA55BM43CC.
Vancouver
1.Elvan Hasanoğlu Özkan, Hamit Emre Kızıl, İffet Şakıyan, Dilek Nartop, Nurşen Sarı, Güleray Ağar. Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine. Gazi University Journal of Science [Internet]. 2018 Jun. 1;31(2):408-14. Available from: https://izlik.org/JA55BM43CC